5 Recruiting Trials

Clinical Trials
for Kidney Disease in Arkansas

5 clinical trials for Kidney Disease are currently recruiting participants at study sites in Arkansas. Study-related care is provided at no cost.

5
Recruiting trials
6
Study sites
2
Cities
5
Industry-sponsored
2
Phase 2
3
Phase 3

Kidney Disease clinical trials in Arkansas: what to expect

Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.

In Arkansas, recruiting kidney disease studies are concentrated in Little Rock and Fayetteville. 5 of the 5 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who kidney disease trials usually look for

Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.

What taking part involves

Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.

Questions worth asking the study team

Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.

Showing 5 of 5 recruiting Kidney Disease trials in Arkansas

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
PHASE3 Huntsville, Alabama +4 sites NCT07753993
This trial is looking for adults with chronic kidney disease to see how well elecoglipron works compared to a placebo. Participants must be on certain medications for their condition before joining the study.
Recruiting
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
PHASE2 Little Rock, Arkansas +4 sites NCT07271186
This trial is looking for adults with diabetic kidney disease to test some new medications. Participants will help researchers understand how safe and effective these medications are.
Recruiting
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
PHASE2 Alabaster, Alabama +4 sites NCT05312879
This trial is looking for adults and children with a specific type of kidney disease caused by genetics. Participants will receive the drug VX-147 to assess its effectiveness and safety.
Recruiting
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
PHASE3 Little Rock, Arkansas +4 sites NCT07624305
This trial is looking for adults with chronic kidney disease stages 3b and 4. Participants will take a daily combination of two medications to see how well they work together compared to taking just one of them.
Recruiting
Persona Revision Knee System Outcomes
N/A Fayetteville, Arkansas +4 sites NCT04821154
This trial is looking for patients who have had knee surgery and need additional treatment. Participants will be evaluated for the safety and effectiveness of the Persona Revision Knee System.
Recruiting

Where the Kidney Disease studies are in Arkansas

  • Research Site, Little Rock2 trials
  • Advanced Orthopaedic Specialists, Fayetteville1 trial
  • Applied Research Center of Arkansas, Little Rock1 trial
  • Bowen Hefley Orthopedics, Little Rock1 trial
  • CHI St. Vincent Heart Clinic Arkansas- Cardiology and Medicine Clinic - Little Rock, Little Rock1 trial
  • UAMS Medical Center - Pulmonology, Little Rock1 trial

Counts are recruiting studies listing at least one site in Arkansas, from ClinicalTrials.gov, refreshed every two days.

Kidney Disease clinical trials in Arkansas: common questions

How many Kidney Disease clinical trials are recruiting in Arkansas?
TrialFinder currently lists 5 recruiting Kidney Disease clinical trials with study sites in Arkansas. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Arkansas?
Study sites for the Kidney Disease trials listed on this page include Little Rock, Fayetteville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in Arkansas?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Arkansas also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Arkansas?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
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Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.

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