8 Recruiting Trials

Clinical Trials
for Arthritis in Arkansas

8 clinical trials for Arthritis are currently recruiting participants at study sites in Arkansas. Study-related care is provided at no cost.

8
Recruiting trials
9
Study sites
4
Cities
7
Industry-sponsored
2
Phase 2
3
Phase 3

Arthritis clinical trials in Arkansas: what to expect

Arthritis trials are split by type. Rheumatoid arthritis studies test biologics, targeted pills and, more recently, cell therapies in people whose joints stay inflamed despite methotrexate or a biologic. Knee osteoarthritis studies test injections meant to slow cartilage loss, new pain medicines, devices and exercise and weight programs. Psoriatic arthritis, ankylosing spondylitis and gout each have their own trials, and a listing will always say which type it enrolls.

In Arkansas, recruiting arthritis studies are concentrated in Jonesboro, Little Rock, Fayetteville and Searcy. 7 of the 8 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who arthritis trials usually look for

Rheumatoid arthritis trials count swollen and tender joints and measure inflammation in the blood at screening, and ask that a standard medicine has not worked well enough; methotrexate usually continues, while a current biologic is stopped after a washout. Knee osteoarthritis trials need an X-ray showing moderate damage, a pain score above a threshold, and no steroid or hyaluronic acid injection in the past few months; many set a weight limit. Ages are usually 18 to 80, and most trials exclude pregnancy and a recent serious infection.

What taking part involves

Screening includes a joint exam, blood work and X-rays or an MRI. Rheumatoid arthritis trials run six to twelve months with visits every four weeks for an injection or infusion and labs; placebo arms are common, with rescue rules so no one stays on an ineffective treatment for long. Osteoarthritis injection trials give one or a few injections at the site and follow you for six to twenty-four months with pain diaries and imaging. Exercise trials involve supervised sessions for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Which of your medicines continue; how long any washout is; the chance of placebo and the rescue rules; how imaging is scheduled; and whether an extension lets everyone receive the active treatment.

Showing 8 of 8 recruiting Arthritis trials in Arkansas

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis
PHASE3 Jonesboro, Arkansas +4 sites NCT06807424
This trial is looking for people with active psoriatic arthritis who have previously tried certain treatments but still have symptoms. Participants will take part in a study to see how well a medication called icotrokinra works compared to a placebo.
Recruiting
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
PHASE3 Avondale, Arizona +4 sites NCT06641089
This trial is looking for adults with active psoriatic arthritis who did not respond well to past treatments. Participants will take sonelokimab or a placebo to see how well it works and if it is safe.
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
PHASE3 Little Rock, Arkansas +4 sites NCT06100744
This trial is looking for children with juvenile psoriatic arthritis (jPsA). Participants will receive either risankizumab or adalimumab as injections and be monitored for their symptoms and safety over time.
Recruiting
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
PHASE2 Jonesboro, Arkansas +4 sites NCT06972446
This trial is looking for patients with rheumatoid arthritis who have not responded to certain treatments. Participants will try new medications and attend regular check-ups to monitor their health.
Recruiting
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
PHASE2 Searcy, Arkansas +4 sites NCT07321873
This trial is looking for adults with active psoriatic arthritis. Participants will take the study drug JNJ-88545223 to see how well it works compared to a placebo.
Recruiting
Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing After Total Knee Arthroplasty (TKA)
NA Little Rock, Arkansas NCT05823727
This trial is looking for adults aged 50 to 75 who are scheduled for knee replacement surgery. Participants will provide blood samples and undergo tests to assess their health before and after surgery.
Recruiting
A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension
N/A Fayetteville, Arkansas +4 sites NCT06040827
This trial is looking for adults who are planning to have total knee replacement surgery due to severe knee pain from osteoarthritis. Participants will be monitored after their surgery to evaluate the treatment's safety and effectiveness.
Recruiting
Persona Revision Knee System Outcomes
N/A Fayetteville, Arkansas +4 sites NCT04821154
This trial is looking for patients who have had knee surgery and need additional treatment. Participants will be evaluated for the safety and effectiveness of the Persona Revision Knee System.
Recruiting

Where the Arthritis studies are in Arkansas

  • Advanced Orthopaedic Specialists, Fayetteville1 trial
  • Arkansas Children's Hospital /ID# 258776, Little Rock1 trial
  • Arthritis And Rheumatism Associates (Ara) - Jonesboro /ID# 272896, Jonesboro1 trial
  • Arthritis and Rheumatism Associates ARA Jonesboro, Jonesboro1 trial
  • Bowen Hefley Orthopedics, Little Rock1 trial
  • Clinical Site, Jonesboro1 trial

Counts are recruiting studies listing at least one site in Arkansas, from ClinicalTrials.gov, refreshed every two days.

Arthritis clinical trials in Arkansas: common questions

How many Arthritis clinical trials are recruiting in Arkansas?
TrialFinder currently lists 8 recruiting Arthritis clinical trials with study sites in Arkansas. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Arthritis clinical trials located in Arkansas?
Study sites for the Arthritis trials listed on this page include Jonesboro, Little Rock, Searcy, Fayetteville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Arthritis clinical trial in Arkansas?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Arthritis trials in Arkansas also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Arthritis clinical trial in Arkansas?
Each study sets its own criteria based on age, Arthritis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Which type of arthritis do trials enroll?
Each listing names one: rheumatoid, osteoarthritis (most often knee), psoriatic, ankylosing spondylitis or gout. Rheumatoid and knee osteoarthritis have the most recruiting trials.
Do I need to stop my arthritis medicine to join a trial?
For rheumatoid arthritis, methotrexate usually continues and a biologic is stopped after a supervised washout. Osteoarthritis trials ask that you have had no joint injection for a few months and may limit daily pain medicine.
Are there arthritis trials that do not involve medicine?
Yes. Exercise, physical therapy, weight management, braces and devices, and diet studies all recruit, mostly for knee and hip osteoarthritis.
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Arthritis trials test biologics, JAK inhibitors, stem-cell therapies, and pain-management protocols for rheumatoid arthritis, osteoarthritis, and psoriatic arthritis.

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