16 Recruiting Trials

Clinical Trials
for Obesity in Arkansas

16 clinical trials for Obesity are currently recruiting participants at study sites in Arkansas. Study-related care is provided at no cost.

16
Recruiting trials
14
Study sites
3
Cities
10
Industry-sponsored
1
Phase 2
10
Phase 3

Obesity clinical trials in Arkansas: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Arkansas, recruiting obesity studies are concentrated in Little Rock, Fayetteville and Fort Smith. 10 of the 16 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 16 of 16 recruiting Obesity trials in Arkansas

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
PHASE3 Birmingham, Alabama +4 sites NCT07654374
This trial is looking for adults with obesity or overweight who also have type 2 diabetes. Participants will take either the drug aleniglipron or a placebo for 76 weeks to assess its effects.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Little Rock, Arkansas +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07743450
This trial is looking for adults with obesity or overweight who have type 2 diabetes. Participants will take a daily oral medication to see how well it works and how safe it is over time.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
PHASE3 Little Rock, Arkansas +4 sites NCT07743463
This trial is looking for adults who are overweight or obese and have weight-related health problems. Participants will take a daily pill for the study to see how well it helps with weight management and its safety.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
PHASE3 Little Rock, Arkansas +4 sites NCT07284979
This trial is looking for individuals living with obesity who have struggled to lose weight through diet and exercise. Participants will receive a weekly injection of ribupatide and will be compared to those receiving semaglutide or a placebo.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
Level Up! (The Combined and Independent Effects of Exercise Training and Dietary Enhancement on Cardiometabolic Health in Adolescents With Obesity)
NA Little Rock, Arkansas +1 sites NCT06848478
This trial is looking for adolescents aged 13 to 17 who are struggling with obesity. Participants will take part in exercise programs and dietary coaching to see how these affect their health over 12 weeks.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
PHASE3 Fairhope, Alabama +4 sites NCT07784270
This trial is looking for adults with type 2 diabetes and obesity or being overweight. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects their body weight.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Little Rock, Arkansas +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
Fasted vs. Fed State Exercise
PHASE2 Fort Smith, Arkansas NCT07487090
This trial is looking for adults who want to lose weight and improve their heart health through exercise. Participants will take part in a 16-week exercise program performed either before or after eating to see which method is more effective.
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
PHASE3 Birmingham, Alabama +4 sites NCT07037459
This trial is looking for adults with heart failure and obesity. Participants will take a new treatment along with their usual heart failure care to see if it helps reduce heart failure problems.
Recruiting
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
PHASE3 Little Rock, Arkansas +4 sites NCT07667803
This trial is looking for adults with obesity or overweight. Participants will take a medication called elecoglipron while following a diet and exercise program to help manage their weight.
Recruiting
We-Move With Windy: Gross Motor Development for Early Childhood
NA Little Rock, Arkansas NCT07346300
This trial is looking for mother-child pairs where the mother has a higher body weight and the child is between 3 and 5 years old. Participants will engage in fun exercise sessions designed to help children develop their physical skills while supporting parents with helpful resources.
Recruiting
Community Expecting: Exercise During Pregnancy
NA Little Rock, Arkansas NCT07343700
This trial is looking for pregnant women who have a BMI of 30 or higher and do not currently meet recommended exercise guidelines. Participants will join a community-based exercise program designed to be safe and beneficial during pregnancy.
Recruiting
Community Translation of the Expecting Study
NA Little Rock, Arkansas NCT04298125
This trial is looking for expecting mothers who are between 11 to 15 weeks pregnant and have a higher body weight. Participants will be involved in a community exercise program that encourages activity and helps test how well it works.
Recruiting
Time Restricted Feeding, Muscle, and Metabolism
NA Fayetteville, Arkansas NCT04949451
This trial is looking for adults aged 25-50 who are overweight or obese. Participants will explore how timing of protein intake affects muscle mass and appetite control.
Recruiting

Where the Obesity studies are in Arkansas

  • Arkansas Children's Nutrition Center, Little Rock2 trials
  • Arkansas Children's Research Institute, Little Rock2 trials
  • Kailera Clinical Site, Little Rock2 trials
  • Research Site, Little Rock2 trials
  • ACCOMPLISH-2 Research Site, Little Rock1 trial
  • AURORA-1 Clinical Site, Little Rock1 trial

Counts are recruiting studies listing at least one site in Arkansas, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Arkansas: common questions

How many Obesity clinical trials are recruiting in Arkansas?
TrialFinder currently lists 16 recruiting Obesity clinical trials with study sites in Arkansas. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Arkansas?
Study sites for the Obesity trials listed on this page include Little Rock, Fort Smith, Fayetteville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Arkansas?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Arkansas also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Arkansas?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Obesity trials near you in Arkansas.

Get Matched — Free
No insurance required

Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

All Obesity trials →