13 Recruiting Trials

Clinical Trials
for Obesity in Nebraska

13 clinical trials for Obesity are currently recruiting participants at study sites in Nebraska. Study-related care is provided at no cost.

13
Recruiting trials
15
Study sites
3
Cities
11
Industry-sponsored
1
Phase 2
10
Phase 3

Obesity clinical trials in Nebraska: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Nebraska, recruiting obesity studies are concentrated in Omaha, Lincoln and Papillion. 11 of the 13 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 13 of 13 recruiting Obesity trials in Nebraska

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
PHASE3 Birmingham, Alabama +4 sites NCT07654374
This trial is looking for adults with obesity or overweight who also have type 2 diabetes. Participants will take either the drug aleniglipron or a placebo for 76 weeks to assess its effects.
Recruiting
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
PHASE3 Canoga Park, California +4 sites NCT07595549
This trial is looking for adults with overweight or obesity who may also have type 2 diabetes. Participants will get either a shot of the study medicine, berobenatide, or a placebo that doesn't contain any medicine. The study lasts for about 20 months and involves regular visits to check on health and weight.
Recruiting
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
PHASE3 Birmingham, Alabama +4 sites NCT07654361
This trial is looking for adults with obesity or overweight who have health problems related to their weight. Participants will take a daily medication called aleniglipron for at least 76 weeks while following a reduced-calorie diet and increasing physical activity.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
PHASE3 Fairhope, Alabama +4 sites NCT07784270
This trial is looking for adults with type 2 diabetes and obesity or being overweight. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects their body weight.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
PHASE2 Mobile, Alabama +4 sites NCT07685808
This trial is looking for adults who are overweight or obese but do not have diabetes. Participants will take an experimental drug called olatorepatide to see how safe it is and how it works in the body.
Recruiting
iAmHealthy Clinical Practice Guideline (CPG)
NA Omaha, Nebraska +3 sites NCT06888011
This trial is looking for children aged 6-11 years who are overweight and live in rural areas. Participants will either receive a program to help with healthy habits or a newsletter during the study.
Recruiting
Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes
NA Lincoln, Nebraska NCT07160530
This trial is looking for young children ages 3 to 5 and their family childcare providers in rural areas to help them eat healthier. Participants will take part in training and coaching sessions focused on improving mealtime practices.
Recruiting
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
PHASE3 Daphne, Alabama +4 sites NCT07037433
This trial is looking for adults with heart disease and obesity. Participants will receive either maridebart cafraglutide or a placebo while continuing usual care.
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
PHASE3 Birmingham, Alabama +4 sites NCT07037459
This trial is looking for adults with heart failure and obesity. Participants will take a new treatment along with their usual heart failure care to see if it helps reduce heart failure problems.
Recruiting

Where the Obesity studies are in Nebraska

  • Bryan Heart, Lincoln3 trials
  • University of Nebraska Medical Center, Omaha2 trials
  • ACCOMPLISH-1 Research Site, Omaha1 trial
  • ACCOMPLISH-2 Research Site, Omaha1 trial
  • Children's Hospital & Medical Center, Omaha1 trial
  • Kailera Clinical Site, Lincoln1 trial

Counts are recruiting studies listing at least one site in Nebraska, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Nebraska: common questions

How many Obesity clinical trials are recruiting in Nebraska?
TrialFinder currently lists 13 recruiting Obesity clinical trials with study sites in Nebraska. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Nebraska?
Study sites for the Obesity trials listed on this page include Omaha, Lincoln. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Nebraska?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Nebraska also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Nebraska?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
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Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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