Hypertension Trials / Trials in Nebraska
14 Recruiting Trials

Clinical Trials
for Hypertension in Nebraska

14 clinical trials for Hypertension are currently recruiting participants at study sites in Nebraska. Study-related care is provided at no cost.

14
Recruiting trials
14
Study sites
3
Cities
10
Industry-sponsored
2
Phase 2
7
Phase 3

Hypertension clinical trials in Nebraska: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In Nebraska, recruiting hypertension studies are concentrated in Omaha, Fremont and Norfolk. 10 of the 14 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 14 of 14 recruiting Hypertension trials in Nebraska

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
PHASE3 Fresno, California +4 sites NCT06274801
This trial is looking for adults who have completed a previous study with seralutinib. Participants will take seralutinib and be monitored for safety and effectiveness over time.
Recruiting
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
PHASE3 Omaha, Nebraska +4 sites NCT07481981
This trial is looking for adults with pulmonary arterial hypertension (PAH) who want to try a new inhalation treatment. Participants will take the treatment once a day for 24 weeks and will be monitored for changes in their exercise ability.
Recruiting
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
PHASE3 Phoenix, Arizona +4 sites NCT07218029
This trial is looking for people who have completed a previous study with sotatercept for pulmonary arterial hypertension (PAH). Participants will be monitored for the long-term safety and tolerance of sotatercept along with their usual PAH treatments.
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
PHASE3 Alexander City, Alabama +4 sites NCT07288398
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
Recruiting
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
PHASE2 Omaha, Nebraska +4 sites NCT07318597
This trial is looking for adults who have been diagnosed with a specific type of high blood pressure in the lungs and who are currently taking stable treatments for it. They should be experiencing mild to moderate limitations in their daily activities. However, people with certain heart or lung diseases, or anyone with a history of severe bleeding issues, won't be eligible to participate.
Recruiting
Postpartum Evaluation of Nifedipine and Enalapril for Hypertension
PHASE4 Omaha, Nebraska NCT07023003
This trial is looking for women who have high blood pressure after giving birth. Participants will take either nifedipine or enalapril to see how well these medications manage their blood pressure and prevent hospital readmission.
Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NA Birmingham, Alabama +4 sites NCT06911632
This trial is looking for adults who are at least 18 years old and have been diagnosed with a specific lung disease. They need to have a certain level of lung function that is low enough, but they can't already have been diagnosed with high blood pressure in the lungs or have certain heart conditions. It's also important that they haven't had a specific heart test in the last year and are generally healthy enough to participate.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
PHASE3 Birmingham, Alabama +4 sites NCT07181109
This trial is looking for adults with high blood pressure that is not well controlled and have either a history of heart disease or are at high risk for heart disease. Participants will receive either the study drug, zilebesiran, or a placebo to see if it lowers the risk of serious heart-related events.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
PHASE2 Omaha, Nebraska +4 sites NCT05937854
This trial is looking for veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs who experience shortness of breath. Participants will take either the drug tadalafil or a placebo and will be monitored over six months to see if their breathing improves.
Recruiting
Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial
PHASE4 Omaha, Nebraska NCT05309460
This trial is looking for women who have high blood pressure after giving birth. Participants will be treated with either Labetalol or Nifedipine to see which works better to reduce complications and hospital readmissions.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NA Phoenix, Arizona +4 sites NCT06526195
This trial is looking for patients with advanced heart failure who are not dependent on intravenous medications. Participants will be evaluated to see if a device called HeartMate 3 can help their heart function better compared to standard medical treatments.
Recruiting
See all 14 Hypertension trials in Nebraska

Where the Hypertension studies are in Nebraska

Research sites running the most studies
  • University of Nebraska Medical Center, Omaha3 trials
  • CHI Health Creighton University Medical Center - Bergan Mercy, Omaha1 trial
  • Clinical Trial Site, Fremont1 trial
  • Clinical Trial Site, Omaha1 trial
  • Methodist Physicians Clinic, Fremont1 trial
  • Methodist Women's Hospital, Omaha1 trial
By city

Counts are recruiting studies listing at least one site in Nebraska, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in Nebraska: common questions

How many Hypertension clinical trials are recruiting in Nebraska?
TrialFinder currently lists 14 recruiting Hypertension clinical trials with study sites in Nebraska. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Nebraska?
Study sites for the Hypertension trials listed on this page include Omaha. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Nebraska?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Nebraska also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Nebraska?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
Hypertension Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Hypertension Trials

Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

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