23 Recruiting Trials

Clinical Trials
for Hypertension in Virginia

23 clinical trials for Hypertension are currently recruiting participants at study sites in Virginia. Study-related care is provided at no cost.

23
Recruiting trials
49
Study sites
16
Cities
19
Industry-sponsored
5
Phase 2
7
Phase 3

Hypertension clinical trials in Virginia: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In Virginia, recruiting hypertension studies are concentrated in Richmond, Norfolk, Falls Church and Manassas, with sites in 12 other cities. 19 of the 23 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 20 of 23 recruiting Hypertension trials in Virginia

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
PHASE2 Phoenix, Arizona +4 sites NCT07090161
This trial is looking for people with uncontrolled high blood pressure. Participants will take either the study drug or a placebo to see if it helps lower their blood pressure.
Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NA Birmingham, Alabama +4 sites NCT06559891
This trial is looking for adults with hypertension who have not been able to control their blood pressure with medication. Participants will stop taking their blood pressure medications for a short time and receive either the TIVUS treatment or a sham procedure.
Recruiting
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
PHASE3 Fresno, California +4 sites NCT06274801
This trial is looking for adults who have completed a previous study with seralutinib. Participants will take seralutinib and be monitored for safety and effectiveness over time.
Recruiting
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
PHASE3 Phoenix, Arizona +4 sites NCT07179380
This trial is looking for adults with pulmonary hypertension linked to interstitial lung disease. Participants will take either a study drug called TPIP or a placebo once a day for 24 weeks and will be monitored for their exercise ability.
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
PHASE3 Alexander City, Alabama +4 sites NCT07288398
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
Recruiting
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
PHASE2 Alexander City, Alabama +4 sites NCT07142356
This trial is looking for adults with high blood pressure that is hard to control. Participants will take either the drug RTN-001 or a placebo (a dummy pill) every day for 12 weeks and visit the clinic for checkups.
Recruiting
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
PHASE1 Scottsdale, Arizona +4 sites NCT06649110
This trial is looking for healthy volunteers and patients diagnosed with pulmonary arterial hypertension (PAH). Participants will receive treatment LTP001 and help researchers learn about its effects.
Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NA Birmingham, Alabama +4 sites NCT06911632
This trial is looking for adults who are at least 18 years old and have been diagnosed with a specific lung disease. They need to have a certain level of lung function that is low enough, but they can't already have been diagnosed with high blood pressure in the lungs or have certain heart conditions. It's also important that they haven't had a specific heart test in the last year and are generally healthy enough to participate.
Recruiting
Pulmonary Hypertension (PH) Biorepository for Translational Research
N/A Falls Church, Virginia +2 sites NCT07647549
Recruiting
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
N/A Birmingham, Alabama +4 sites NCT06388421
This trial is looking for adults with pulmonary hypertension related to interstitial lung disease. Participants will share information about their health and treatments to help improve understanding of these conditions.
Recruiting
Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG
N/A Norfolk, Virginia +3 sites NCT07087613
This trial is looking for adults who have had a heart test recently. Participants will help researchers see if new technology can find heart problems based on heart sounds and an ECG.
Recruiting
Pulmonary Hypertension Association Registry
N/A Phoenix, Arizona +4 sites NCT04071327
This trial is looking for people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). Participants will provide information about their health and treatment to help improve care for these conditions.
Recruiting
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NA Scottsdale, Arizona +4 sites NCT06059638
This trial is looking for people with high blood pressure who need a pacemaker. Participants will try a new treatment that adjusts heart rhythms to help lower blood pressure.
Recruiting
Global Paradise System US Post Approval Study
N/A Long Beach, California +4 sites NCT06297291
This trial is looking for adults with high blood pressure that isn't controlled by lifestyle changes or medications. Participants will receive treatment with the Paradise Ultrasound Renal Denervation System and help researchers understand its long-term safety and effectiveness.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
PHASE3 Birmingham, Alabama +4 sites NCT07181109
This trial is looking for adults with high blood pressure that is not well controlled and have either a history of heart disease or are at high risk for heart disease. Participants will receive either the study drug, zilebesiran, or a placebo to see if it lowers the risk of serious heart-related events.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
Autonomic and Renal Contributions to Hypertension With ADT
PHASE4 Richmond, Virginia NCT07848828
This trial is looking for men with prostate cancer who are 40 years or older and want to learn about how treatment might affect their blood pressure. Participants will undergo evaluation and monitoring related to their heart and kidney function while using androgen deprivation therapy for their cancer treatment.
Recruiting
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
PHASE2 Huntsville, Alabama +4 sites NCT07783802
This trial is looking for adults with high levels of inflammation and increased risk for heart issues. Participants will take clazakizumab or a placebo for about 9 months to see how it affects inflammation levels in the body.
Recruiting

Where the Hypertension studies are in Virginia

  • Virginia Commonwealth University, Richmond3 trials
  • Pulmonary Associates of Richmond, Inc., Richmond2 trials
  • Sentara Norfolk General Hospital, Norfolk2 trials
  • Carient Heart & Vascular - Manassas, Manassas1 trial
  • Carient Heart and Vascular, Manassas1 trial
  • Carient Heart and Vascular LLC-Reston, Reston1 trial

Counts are recruiting studies listing at least one site in Virginia, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in Virginia: common questions

How many Hypertension clinical trials are recruiting in Virginia?
TrialFinder currently lists 23 recruiting Hypertension clinical trials with study sites in Virginia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Virginia?
Study sites for the Hypertension trials listed on this page include Falls Church, Norfolk, Richmond. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Virginia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Virginia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Virginia?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Hypertension trials near you in Virginia.

Get Matched — Free
No insurance required

Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

All Hypertension trials →