12 Recruiting Trials

Clinical Trials
for Hypertension in Rhode Island

12 clinical trials for Hypertension are currently recruiting participants at study sites in Rhode Island. Study-related care is provided at no cost.

12
Recruiting trials
16
Study sites
6
Cities
5
Industry-sponsored
3
Phase 2
3
Phase 3

Hypertension clinical trials in Rhode Island: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In Rhode Island, recruiting hypertension studies are concentrated in Providence, East Providence, Newport and Wakefield, with sites in 2 other cities. 5 of the 12 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 12 of 12 recruiting Hypertension trials in Rhode Island

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
PHASE3 Phoenix, Arizona +4 sites NCT07218029
This trial is looking for people who have completed a previous study with sotatercept for pulmonary arterial hypertension (PAH). Participants will be monitored for the long-term safety and tolerance of sotatercept along with their usual PAH treatments.
Recruiting
A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults
PHASE1 Providence, Rhode Island +3 sites NCT07143448
This trial is looking for adults with pulmonary arterial hypertension (PAH) who are already on certain medications for their condition. Participants will receive an additional treatment and be closely monitored during the trial.
Recruiting
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
PHASE2 Santa Barbara, California +4 sites NCT07333183
This trial is looking for people with pulmonary hypertension related to lung disease who are already using inhaled treprostinil. Participants will take inhaled mosliciguat to see how safe and tolerable it is in this situation.
Recruiting
Rhode Island - Statewide Postpartum Hypertension Remote Surveillance
NA Newport, Rhode Island +4 sites NCT06842875
This trial is looking for postpartum patients in Rhode Island who have had high blood pressure during or after pregnancy. Participants will help test a new care model that uses technology to manage their blood pressure compared to a standard method.
Recruiting
Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
N/A Providence, Rhode Island +1 sites NCT07132788
This trial is looking for people with pulmonary arterial hypertension (PAH) to learn how muscle loss affects them. Participants will have various tests and follow-up visits over 6 months to gather information about their condition and health.
Recruiting
Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope
N/A Providence, Rhode Island +2 sites NCT05873387
This trial is looking for adults over 18 who are referred for heart tests. Participants will help researchers see if a special stethoscope can identify pulmonary hypertension.
Recruiting
Pulmonary Hypertension Association Registry
N/A Phoenix, Arizona +4 sites NCT04071327
This trial is looking for people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). Participants will provide information about their health and treatment to help improve care for these conditions.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
PHASE2 Providence, Rhode Island +4 sites NCT05937854
This trial is looking for veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs who experience shortness of breath. Participants will take either the drug tadalafil or a placebo and will be monitored over six months to see if their breathing improves.
Recruiting
Cardiovascular Protection After Preeclampsia With Enalapril
PHASE3 Providence, Rhode Island NCT07222852
This trial is looking for postpartum women who have high blood pressure related to pregnancy. Participation involves being assigned to different blood pressure medications after giving birth and seeing how they affect blood pressure levels.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
PHASE4 Birmingham, Alabama +4 sites NCT06468202
This trial is looking for pregnant individuals at risk of high blood pressure issues. Participants will take either a low or high dose of aspirin to see which is more effective in preventing these conditions.
Recruiting

Where the Hypertension studies are in Rhode Island

  • Rhode Island Hospital, Providence4 trials
  • Brown University, Providence1 trial
  • Clinical Research Site, Providence1 trial
  • Investigational Site-104, Providence1 trial
  • Kent Hospital, Warwick1 trial
  • Landmark Hospital, Woonsocket1 trial

Counts are recruiting studies listing at least one site in Rhode Island, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in Rhode Island: common questions

How many Hypertension clinical trials are recruiting in Rhode Island?
TrialFinder currently lists 12 recruiting Hypertension clinical trials with study sites in Rhode Island. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Rhode Island?
Study sites for the Hypertension trials listed on this page include Providence, Newport. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Rhode Island?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Rhode Island also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Rhode Island?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Hypertension trials near you in Rhode Island.

Get Matched — Free
No insurance required

Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

All Hypertension trials →