25 Recruiting Trials
Clinical Trials
for Hypertension in Alabama
25 clinical trials for Hypertension are currently recruiting participants at study sites in Alabama. Study-related care is provided at no cost.
25
Recruiting trials
24
Study sites
10
Cities
12
Industry-sponsored
4
Phase 2
6
Phase 3
Hypertension clinical trials in Alabama: what to expect
High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.
In Alabama, recruiting hypertension studies are concentrated in Birmingham, Fairhope, Alexander City and Anniston, with sites in 6 other cities. 12 of the 25 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who hypertension trials usually look for
Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.
What taking part involves
Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.
Questions worth asking the study team
Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.
Showing 20 of 25 recruiting Hypertension trials in Alabama
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Recruiting
This trial is looking for adults with hypertension who have not been able to control their blood pressure with medication. Participants will stop taking their blood pressure medications for a short time and receive either the TIVUS treatment or a sham procedure.
Early Time-Restricted Eating in Older Adults With Hypertension
Recruiting
This trial is looking for older adults with high blood pressure to see how eating at specific early times affects their health. Participants should be willing to follow a set eating schedule over several weeks.
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Recruiting
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Recruiting
This trial is looking for adults with high blood pressure that is hard to control. Participants will take either the drug RTN-001 or a placebo (a dummy pill) every day for 12 weeks and visit the clinic for checkups.
Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project
Recruiting
This trial is looking for pregnant women with mild high blood pressure. Participants will either receive treatment to lower their blood pressure or usual care during their pregnancy.
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Recruiting
This trial is looking for adults who are at least 18 years old and have been diagnosed with a specific lung disease. They need to have a certain level of lung function that is low enough, but they can't already have been diagnosed with high blood pressure in the lungs or have certain heart conditions. It's also important that they haven't had a specific heart test in the last year and are generally healthy enough to participate.
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Recruiting
This trial is looking for adults with pulmonary hypertension related to interstitial lung disease. Participants will share information about their health and treatments to help improve understanding of these conditions.
Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure
Recruiting
This trial is looking for adults aged 18 to 55 with high blood pressure and poor heart health. Participants will receive either standard care or information about their genetic risk for high blood pressure, along with support to make healthier choices over a year.
Arterial Stiffness and Blood Pressure
Recruiting
This trial is looking for older veterans who have high blood pressure. Participants will be randomly assigned to different blood pressure treatment methods and will undergo tests to measure their blood vessel stiffness.
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Recruiting
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Recruiting
This trial is looking for adults with high blood pressure that is not well controlled and have either a history of heart disease or are at high risk for heart disease. Participants will receive either the study drug, zilebesiran, or a placebo to see if it lowers the risk of serious heart-related events.
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Recruiting
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
Recruiting
This trial is looking for infants born very preterm who have a lung condition called pulmonary hypertension. Taking part may involve receiving different amounts of supplemental oxygen to see if it helps improve their health.
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
Recruiting
This trial is looking for obese adults with high blood pressure. Participants will be involved in research that aims to improve blood pressure treatment timing based on body rhythms.
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Recruiting
This trial is looking for adults with high levels of inflammation and increased risk for heart issues. Participants will take clazakizumab or a placebo for about 9 months to see how it affects inflammation levels in the body.
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
Recruiting
This trial is looking for adults with chronic low back pain and high blood pressure. Participants will receive a treatment called epidural spinal cord stimulation and will need to visit a research lab and provide blood samples.
Inspire HER: Inspiring the Heart and Emotions for Radical Health
Recruiting
This trial is looking for Black women aged 30 to 79 who want to improve their heart health. Participants will take part in a program that offers health education, physical activity, and support resources.
CARBON: UAB Cardiovascular Research Biobank
Recruiting
This trial is looking for adults who want to contribute health information and biological samples for future research. Participants will provide DNA samples and health data over time.
Where the Hypertension studies are in Alabama
Research sites running the most studies
- University of Alabama at Birmingham, Birmingham11 trials
- Pinnacle Research Group, LLC, Anniston2 trials
- Birmingham VA Medical Center, Birmingham, AL, Birmingham1 trial
- Cahaba Research - Pelham, Pelham1 trial
- Cardiology, PC, Birmingham1 trial
- Central Research Associates, Birmingham1 trial
By city
Counts are recruiting studies listing at least one site in Alabama, from ClinicalTrials.gov, refreshed every two days.
Hypertension clinical trials in Alabama: common questions
How many Hypertension clinical trials are recruiting in Alabama?
TrialFinder currently lists 25 recruiting Hypertension clinical trials with study sites in Alabama. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Alabama?
Study sites for the Hypertension trials listed on this page include Birmingham, Alexander City, Fairhope, Anniston, Foley, Huntsville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Alabama?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Alabama also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Alabama?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Hypertension Trials
Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.
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