15 Recruiting Trials

Clinical Trials
for Hypertension in Connecticut

15 clinical trials for Hypertension are currently recruiting participants at study sites in Connecticut. Study-related care is provided at no cost.

15
Recruiting trials
19
Study sites
10
Cities
10
Industry-sponsored
2
Phase 2
4
Phase 3

Hypertension clinical trials in Connecticut: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In Connecticut, recruiting hypertension studies are concentrated in New Haven, Bridgeport, Waterbury and Farmington, with sites in 6 other cities. 10 of the 15 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 15 of 15 recruiting Hypertension trials in Connecticut

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
NA New Haven, Connecticut +4 sites NCT07214376
This trial is looking for patients with heart failure and pulmonary hypertension. Participants will receive a specific treatment and be monitored for three years to evaluate safety and effectiveness.
Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NA Birmingham, Alabama +4 sites NCT06559891
This trial is looking for adults with hypertension who have not been able to control their blood pressure with medication. Participants will stop taking their blood pressure medications for a short time and receive either the TIVUS treatment or a sham procedure.
Recruiting
LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
PHASE2 New Haven, Connecticut +3 sites NCT05798923
This trial is looking for adults aged 18 to 80 with pulmonary hypertension related to interstitial lung disease. Participants will take the study drug and go through regular check-ups to monitor their health and treatment effects.
Recruiting
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
PHASE2 Alexander City, Alabama +4 sites NCT07142356
This trial is looking for adults with high blood pressure that is hard to control. Participants will take either the drug RTN-001 or a placebo (a dummy pill) every day for 12 weeks and visit the clinic for checkups.
Recruiting
Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
NA New Haven, Connecticut +2 sites NCT05884190
This trial is looking for women who have recently given birth and may experience high blood pressure after delivery. Participants will receive different care approaches to help detect and manage postpartum hypertension and related health issues.
Recruiting
An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
N/A Phoenix, Arizona +4 sites NCT06129240
This trial is looking for people with pulmonary hypertension related to interstitial lung disease. Participants will take part in a treatment involving inhaled medication and undergo assessments to monitor their health.
Recruiting
Pulmonary Hypertension Association Registry
N/A Phoenix, Arizona +4 sites NCT04071327
This trial is looking for people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). Participants will provide information about their health and treatment to help improve care for these conditions.
Recruiting
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
NA Farmington, Connecticut +2 sites NCT07238556
This trial is looking for patients with risk factors for heart disease. Participants will work with their doctors to follow an exercise plan for 12 weeks and share their experiences.
Recruiting
Global Paradise System US Post Approval Study
N/A Long Beach, California +4 sites NCT06297291
This trial is looking for adults with high blood pressure that isn't controlled by lifestyle changes or medications. Participants will receive treatment with the Paradise Ultrasound Renal Denervation System and help researchers understand its long-term safety and effectiveness.
Recruiting
The Effects of Brief Periods of Exercise on Blood Pressure
NA West Hartford, Connecticut NCT07453550
This trial is looking for adults aged 18 to 55 with high blood pressure. Participants will engage in short periods of exercise to see how it affects their blood pressure.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
PHASE3 Birmingham, Alabama +4 sites NCT07181109
This trial is looking for adults with high blood pressure that is not well controlled and have either a history of heart disease or are at high risk for heart disease. Participants will receive either the study drug, zilebesiran, or a placebo to see if it lowers the risk of serious heart-related events.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
NA New Haven, Connecticut +1 sites NCT06373289
This trial is looking for infants born very preterm who have a lung condition called pulmonary hypertension. Taking part may involve receiving different amounts of supplemental oxygen to see if it helps improve their health.
Recruiting
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
PHASE3 Anniston, Alabama +4 sites NCT07794579
This trial is looking for people who are overweight and at risk of developing obesity-related health issues. Participants will take orforglipron and will be monitored to see if it helps reduce these risks.
Recruiting

Where the Hypertension studies are in Connecticut

  • Yale New Haven Hospital, New Haven3 trials
  • Bridgeport Hosptial, Bridgeport1 trial
  • CMR of Greater New Haven, LLC, Hamden1 trial
  • Cardiology Associates of Fairfield County, Stamford1 trial
  • Cardiology Physicians of Fairfield County - Bridgeport, Bridgeport1 trial
  • Chase Medical Research, LLC, Waterbury1 trial

Counts are recruiting studies listing at least one site in Connecticut, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in Connecticut: common questions

How many Hypertension clinical trials are recruiting in Connecticut?
TrialFinder currently lists 15 recruiting Hypertension clinical trials with study sites in Connecticut. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Connecticut?
Study sites for the Hypertension trials listed on this page include New Haven, Farmington, West Hartford. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Connecticut?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Connecticut also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Connecticut?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
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Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

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