48 Recruiting Trials

Clinical Trials
for Diabetes in Connecticut

48 clinical trials for Diabetes are currently recruiting participants at study sites in Connecticut. Study-related care is provided at no cost.

48
Recruiting trials
37
Study sites
11
Cities
24
Industry-sponsored
9
Phase 2
17
Phase 3

Diabetes clinical trials in Connecticut: what to expect

Diabetes is one of the largest areas of clinical research, and the trials differ a great deal by type. Type 2 studies most often test new glucose-lowering or weight-reducing medicines, once-weekly insulins, and combinations with GLP-1 drugs, in people whose A1c is above goal on their current treatment. Type 1 studies test automated insulin delivery systems, immune therapies for people recently diagnosed or at high risk, and cell-based approaches. Others focus on the complications: kidney disease, eye disease, nerve pain and foot ulcers.

In Connecticut, recruiting diabetes studies are concentrated in New Haven, Bridgeport, Stamford and Waterbury, with sites in 7 other cities. 24 of the 48 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who diabetes trials usually look for

Type 2 trials typically ask for a confirmed diagnosis, an A1c in a stated range (often between 7 and 10.5 percent) and a stable dose of your current medicines for at least a few months. Many exclude recent insulin use, a recent heart attack or stroke, or kidney function below a cut-off. Type 1 trials are often limited by time since diagnosis and by age, and some enroll children and teenagers with a parent's consent.

You do not need to know your A1c or kidney numbers to ask about a trial; the site measures them at screening.

What taking part involves

Screening includes blood work and a review of your history. Medicine trials usually last six months to three years with visits every one to three months, and many provide a glucose monitor and supplies for the duration. Some compare a new drug with a standard one rather than a placebo, so everyone receives active treatment; others include a placebo arm, and the consent form says which. Study drugs, devices, visits and labs are provided at no cost, and most trials pay for time and travel.

Questions worth asking the study team

Whether you would stay on your current medicines; whether there is a placebo group; how often visits are and whether any can be done remotely; and whether your own doctor will receive the results of study labs. If you have type 1 diabetes, ask whether the study uses your own pump or monitor.

Showing 20 of 48 recruiting Diabetes trials in Connecticut

Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment
PHASE2 New Haven, Connecticut NCT06411210
This trial is looking for young adults aged 18-30 with type 1 diabetes and obesity. Participants will receive GLP-1 analogue treatment to see how it affects their heart and metabolic health.
Recruiting
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
PHASE3 Birmingham, Alabama +4 sites NCT07662213
This trial is looking for adults with type 2 diabetes who struggle to manage their condition. Participants will compare the effectiveness of a new drug, elecoglipron, with an existing treatment, semaglutide.
Recruiting
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
PHASE3 New Haven, Connecticut +4 sites NCT07282613
This trial is looking for children and teenagers with type 2 diabetes. Participants will receive either a new medicine called CagriSema or a placebo for part of the study, and then everyone will receive CagriSema for the second part.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
PHASE3 New Haven, Connecticut +4 sites NCT07088068
This trial is looking for young people ages 1 to 25 who have recently been diagnosed with stage 3 type 1 diabetes. Participants will receive either teplizumab or a placebo through an IV to see how it affects their blood sugar control over 52 weeks.
Recruiting
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
PHASE3 Gilbert, Arizona +4 sites NCT07817251
This trial is looking for adults with type 2 diabetes who are currently stable on a specific diabetes injection. Participants will switch to a new treatment called CagriSema for about 6 months to see how well they tolerate it.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
PHASE3 Birmingham, Alabama +4 sites NCT07662044
This trial is looking for adults with type 2 diabetes that is not well controlled. Participants will take elecoglipron alone or with another medication and compare the effects to a placebo.
Recruiting
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
PHASE3 Tucson, Arizona +4 sites NCT06739122
This trial is looking for children with Type 2 diabetes to test different doses of a medication called dulaglutide. Participation will last about 8 months and requires being treated with certain diabetes medications.
Recruiting
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
PHASE1 New Haven, Connecticut +4 sites NCT07061574
This trial is looking for young people aged 9 to under 21 who have recently been diagnosed with Type 1 Diabetes. Participants will receive a treatment called anti-thymocyte globulin (ATG) followed by either adalimumab or verapamil to see how well it helps preserve insulin secretion over two years.
Recruiting
Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
PHASE2 New Haven, Connecticut +4 sites NCT07216391
This trial is looking for people aged 4 to 34 who have early signs of Type 1 diabetes. Participants will receive either two infusions of ATG or 14 infusions of teplizumab and will be followed for up to 9 years.
Recruiting
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
PHASE2 New Haven, Connecticut +4 sites NCT07142252
This trial is looking for people recently diagnosed with type 1 diabetes. Participants will take either the study drug or a placebo every two weeks for 26 weeks, followed by a 6-month check-up.
Recruiting
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
PHASE2 New Haven, Connecticut +4 sites NCT07224321
This trial is looking for young people aged 6 to under 18 with newly diagnosed type 1 diabetes. Participants will take a medication called Afrezza along with another insulin for 13 weeks, with a possible option to continue for another 26 weeks.
Recruiting
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
PHASE2 Birmingham, Alabama +4 sites NCT05762107
This trial is looking for adults with type 1 diabetes who experience low blood sugar at night. Participants will receive either the study drug ZT-01 or a placebo for two weeks while using a glucose monitor to track their blood sugar levels.
Recruiting
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
PHASE4 New Haven, Connecticut +4 sites NCT06445946
This trial is looking for pregnant women who are at least 18 years old and have been diagnosed with gestational diabetes, needing medication to manage their blood sugar. It’s important that they do not have any serious kidney problems or other specific health conditions that could complicate the study. Women are also excluded if they have certain fetal conditions or previous diabetes issues before pregnancy.
Recruiting
Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes
NA Chula Vista, California +4 sites NCT07864168
This trial is looking for patients aged 2 to 80 with type 1 or type 2 diabetes. Participants will wear a sensor and provide blood samples during the study.
Recruiting
Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus (T2DM)
NA New Haven, Connecticut NCT05776563
This trial is looking for adults with type 2 diabetes to understand how better control of blood sugar affects the brain. Participants will be monitored over 12 weeks to see if improving blood sugar levels can help reverse some brain changes.
Recruiting
Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System
NA New Haven, Connecticut +4 sites NCT07579702
This trial is looking for people aged 14 to 75 with type 1 or type 2 diabetes who have trouble controlling their blood sugar. Participants will use the Omnipod 6 System to see how well it works compared to the Omnipod 5 System.
Recruiting
Building and Sustaining Exercise Habits for Adults With Type 1 Diabetes
NA New Haven, Connecticut NCT06967701
This trial is looking for adults with type 1 diabetes who want to exercise more but find it challenging. Participants will use a mobile app that helps track their blood sugar, exercise, and mood to support their fitness journey.
Recruiting

Where the Diabetes studies are in Connecticut

  • Yale University, New Haven10 trials
  • Yale School of Medicine, New Haven4 trials
  • Yale University School of Medicine, New Haven4 trials
  • CMR of Greater New Haven, LLC, Hamden2 trials
  • Chase Medical Research, LLC, Waterbury2 trials
  • Kailera Clinical Site, Stamford2 trials

Counts are recruiting studies listing at least one site in Connecticut, from ClinicalTrials.gov, refreshed every two days.

Diabetes clinical trials in Connecticut: common questions

How many Diabetes clinical trials are recruiting in Connecticut?
TrialFinder currently lists 48 recruiting Diabetes clinical trials with study sites in Connecticut. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Diabetes clinical trials located in Connecticut?
Study sites for the Diabetes trials listed on this page include New Haven, Stamford. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Diabetes clinical trial in Connecticut?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Diabetes trials in Connecticut also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Diabetes clinical trial in Connecticut?
Each study sets its own criteria based on age, Diabetes diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a diabetes clinical trial if I am already on medication?
Usually yes. Most type 2 diabetes trials enroll people on metformin or other oral medicines and test a new treatment on top of them; some require a stable dose for a few months first. Trials that exclude insulin or a specific drug say so in their criteria.
Do I need to know my A1c to apply?
No. Trials state an A1c range, but the study site measures it at the screening visit. You only need to know that you have been diagnosed and which type.
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Diabetes clinical trials study new treatments for Type 1, Type 2, and gestational diabetes, including insulin therapies, diet interventions, and islet-cell transplants.

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