10 Recruiting Trials

Clinical Trials
for Diabetes in South Dakota

10 clinical trials for Diabetes are currently recruiting participants at study sites in South Dakota. Study-related care is provided at no cost.

10
Recruiting trials
9
Study sites
3
Cities
5
Industry-sponsored
1
Phase 2
5
Phase 3

Diabetes clinical trials in South Dakota: what to expect

Diabetes is one of the largest areas of clinical research, and the trials differ a great deal by type. Type 2 studies most often test new glucose-lowering or weight-reducing medicines, once-weekly insulins, and combinations with GLP-1 drugs, in people whose A1c is above goal on their current treatment. Type 1 studies test automated insulin delivery systems, immune therapies for people recently diagnosed or at high risk, and cell-based approaches. Others focus on the complications: kidney disease, eye disease, nerve pain and foot ulcers.

In South Dakota, recruiting diabetes studies are concentrated in Sioux Falls, Rapid City and Dakota Dunes. 5 of the 10 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who diabetes trials usually look for

Type 2 trials typically ask for a confirmed diagnosis, an A1c in a stated range (often between 7 and 10.5 percent) and a stable dose of your current medicines for at least a few months. Many exclude recent insulin use, a recent heart attack or stroke, or kidney function below a cut-off. Type 1 trials are often limited by time since diagnosis and by age, and some enroll children and teenagers with a parent's consent.

You do not need to know your A1c or kidney numbers to ask about a trial; the site measures them at screening.

What taking part involves

Screening includes blood work and a review of your history. Medicine trials usually last six months to three years with visits every one to three months, and many provide a glucose monitor and supplies for the duration. Some compare a new drug with a standard one rather than a placebo, so everyone receives active treatment; others include a placebo arm, and the consent form says which. Study drugs, devices, visits and labs are provided at no cost, and most trials pay for time and travel.

Questions worth asking the study team

Whether you would stay on your current medicines; whether there is a placebo group; how often visits are and whether any can be done remotely; and whether your own doctor will receive the results of study labs. If you have type 1 diabetes, ask whether the study uses your own pump or monitor.

Showing 10 of 10 recruiting Diabetes trials in South Dakota

Together Overcoming Diabetes - Great Plains
NA Rapid City, South Dakota NCT06770673
This trial is looking for American Indian or Alaska Native adults and youth who are caregivers for someone with type 2 diabetes. Participants will receive a diabetes intervention and complete follow-up assessments.
Recruiting
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
PHASE3 New Haven, Connecticut +4 sites NCT07282613
This trial is looking for children and teenagers with type 2 diabetes. Participants will receive either a new medicine called CagriSema or a placebo for part of the study, and then everyone will receive CagriSema for the second part.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
Type 1 Diabetes Extension Study
N/A San Francisco, California +4 sites NCT02734277
This trial is looking for people who have previously participated in a type 1 diabetes study. Taking part means we will follow you to see how long you continue to produce insulin and how your immune system changes over time.
Recruiting
General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery
N/A Sioux Falls, South Dakota +3 sites NCT04477928
This trial is looking for children to participate in a screening for Type 1 Diabetes and celiac disease. Participants will be screened during their routine health care visits at a Sanford facility.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
PHASE3 Guntersville, Alabama +4 sites NCT07351058
This trial is looking for people with obesity or overweight and type 2 diabetes. Participants will use an injectable medication to help with weight management.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07351045
This trial is looking for adults who are overweight or have obesity without type 2 diabetes. Participants will take a study drug or a placebo to help with weight management and will need to self-administer the treatment.
Recruiting
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
PHASE3 Birmingham, Alabama +4 sites NCT07667803
This trial is looking for adults with obesity or overweight. Participants will take a medication called elecoglipron while following a diet and exercise program to help manage their weight.
Recruiting
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
PHASE2 Mobile, Alabama +4 sites NCT06368817
This trial is looking for children and young adults aged 3 to 30 who have been newly diagnosed with a specific type of brain tumor called germinoma. They need to have certain health markers confirming their condition, and most importantly, they should not have any other major health issues that might interfere with the study. If you're within this age range and have the right diagnosis, you could be a good fit for the trial.
Recruiting
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
N/A Sioux Falls, South Dakota +1 sites NCT01793168
This trial is looking for people who have a rare disease or are affected by a rare/uncommon condition. Participants will join a registry to help researchers connect and advance treatments for these rare diseases.
Recruiting

Where the Diabetes studies are in South Dakota

  • Circle Clinical Research, Sioux Falls2 trials
  • Center for Indigenous Health - Great Plains Hub, Rapid City1 trial
  • Dunes Clinical Research, Dakota Dunes1 trial
  • Monument Health Clinical Rsrch, Rapid City1 trial
  • Research Site, Rapid City1 trial
  • Sanford Health, Sioux Falls1 trial

Counts are recruiting studies listing at least one site in South Dakota, from ClinicalTrials.gov, refreshed every two days.

Diabetes clinical trials in South Dakota: common questions

How many Diabetes clinical trials are recruiting in South Dakota?
TrialFinder currently lists 10 recruiting Diabetes clinical trials with study sites in South Dakota. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Diabetes clinical trials located in South Dakota?
Study sites for the Diabetes trials listed on this page include Rapid City, Sioux Falls. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Diabetes clinical trial in South Dakota?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Diabetes trials in South Dakota also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Diabetes clinical trial in South Dakota?
Each study sets its own criteria based on age, Diabetes diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a diabetes clinical trial if I am already on medication?
Usually yes. Most type 2 diabetes trials enroll people on metformin or other oral medicines and test a new treatment on top of them; some require a stable dose for a few months first. Trials that exclude insulin or a specific drug say so in their criteria.
Do I need to know my A1c to apply?
No. Trials state an A1c range, but the study site measures it at the screening visit. You only need to know that you have been diagnosed and which type.
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Diabetes clinical trials study new treatments for Type 1, Type 2, and gestational diabetes, including insulin therapies, diet interventions, and islet-cell transplants.

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