Diabetes Trials / Trials in Indiana
42 Recruiting Trials

Clinical Trials
for Diabetes in Indiana

42 clinical trials for Diabetes are currently recruiting participants at study sites in Indiana. Study-related care is provided at no cost.

42
Recruiting trials
41
Study sites
13
Cities
23
Industry-sponsored
15
Phase 2
9
Phase 3

Diabetes clinical trials in Indiana: what to expect

Diabetes is one of the largest areas of clinical research, and the trials differ a great deal by type. Type 2 studies most often test new glucose-lowering or weight-reducing medicines, once-weekly insulins, and combinations with GLP-1 drugs, in people whose A1c is above goal on their current treatment. Type 1 studies test automated insulin delivery systems, immune therapies for people recently diagnosed or at high risk, and cell-based approaches. Others focus on the complications: kidney disease, eye disease, nerve pain and foot ulcers.

In Indiana, recruiting diabetes studies are concentrated in Indianapolis, Evansville, Franklin and Greenfield, with sites in 9 other cities. 23 of the 42 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who diabetes trials usually look for

Type 2 trials typically ask for a confirmed diagnosis, an A1c in a stated range (often between 7 and 10.5 percent) and a stable dose of your current medicines for at least a few months. Many exclude recent insulin use, a recent heart attack or stroke, or kidney function below a cut-off. Type 1 trials are often limited by time since diagnosis and by age, and some enroll children and teenagers with a parent's consent.

You do not need to know your A1c or kidney numbers to ask about a trial; the site measures them at screening.

What taking part involves

Screening includes blood work and a review of your history. Medicine trials usually last six months to three years with visits every one to three months, and many provide a glucose monitor and supplies for the duration. Some compare a new drug with a standard one rather than a placebo, so everyone receives active treatment; others include a placebo arm, and the consent form says which. Study drugs, devices, visits and labs are provided at no cost, and most trials pay for time and travel.

Questions worth asking the study team

Whether you would stay on your current medicines; whether there is a placebo group; how often visits are and whether any can be done remotely; and whether your own doctor will receive the results of study labs. If you have type 1 diabetes, ask whether the study uses your own pump or monitor.

Showing 20 of 42 recruiting Diabetes trials in Indiana

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
NA Indianapolis, Indiana NCT05643144
This trial is looking for patients with both dementia and diabetes who want to learn better ways to manage their condition. Participants will use a device that monitors their blood sugar for 14 days and answer some questions about their diabetes management.
Recruiting
Miniaturized Breath-based Sensor for the Detection of Hypo- and Hyperglycemia
NA Indianapolis, Indiana NCT07696273
This trial is looking for young people aged 7-25 with diabetes to help test a new breath sensor. Participants will provide breath samples and share their continuous glucose monitoring data during a diabetes camp in Indiana.
Recruiting
Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events
NA Indianapolis, Indiana NCT06893341
This trial is looking for teenagers with type 1 diabetes who use a continuous glucose monitor. Participants will help test a device that detects blood sugar events by analyzing their breath.
Recruiting
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
PHASE3 Birmingham, Alabama +4 sites NCT07662213
This trial is looking for adults with type 2 diabetes who struggle to manage their condition. Participants will compare the effectiveness of a new drug, elecoglipron, with an existing treatment, semaglutide.
Recruiting
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
PHASE3 New Haven, Connecticut +4 sites NCT07282613
This trial is looking for children and teenagers with type 2 diabetes. Participants will receive either a new medicine called CagriSema or a placebo for part of the study, and then everyone will receive CagriSema for the second part.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
PHASE3 Birmingham, Alabama +4 sites NCT07797335
This trial is looking for adults with type 2 diabetes who are at high risk for heart problems. Participants will receive injections of either zenagamtide or insulin glargine once a week to see which works better for controlling blood sugar and weight.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
PHASE3 Huntsville, Alabama +4 sites NCT07662109
This trial is looking for adults with Type 2 Diabetes who have been managing their condition for at least three months but still need better control. They're particularly interested in those whose blood sugar levels are in a specific range and who have a body weight that meets certain guidelines. However, they’re not accepting people with certain serious health issues, like a history of severe low blood sugar or specific types of diabetes other than Type 2.
Recruiting
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
PHASE3 Tucson, Arizona +4 sites NCT06739122
This trial is looking for children with Type 2 diabetes to test different doses of a medication called dulaglutide. Participation will last about 8 months and requires being treated with certain diabetes medications.
Recruiting
Denosumab for Type 1 Diabetes
PHASE1 Indianapolis, Indiana +2 sites NCT06524960
This trial is looking for people with early type 1 diabetes. Participants will receive treatment with denosumab to see if it helps protect insulin-producing cells and improve blood sugar control.
Recruiting
Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
PHASE2 Mesa, Arizona +4 sites NCT07527650
This trial is looking for adults with type 2 diabetes to test a new treatment called HM15275. Participants will be monitored for 36 weeks to see how well the treatment works and if it is safe.
Recruiting
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
PHASE1 Los Angeles, California +4 sites NCT07061574
This trial is looking for young people aged 9 to under 21 who have recently been diagnosed with Type 1 Diabetes. Participants will receive a treatment called anti-thymocyte globulin (ATG) followed by either adalimumab or verapamil to see how well it helps preserve insulin secretion over two years.
Recruiting
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
PHASE2 San Francisco, California +4 sites NCT07187531
This trial is looking for people aged 5 to 40 who have recently been diagnosed with Type 1 Diabetes. Participants will receive either the study medication or a placebo and will be monitored for safety and effectiveness.
Recruiting
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
PHASE2 Phoenix, Arizona +4 sites NCT06897475
This trial is looking for adults with type 2 diabetes who have certain blood sugar levels and are managing their condition with specific injectable medications. They should also have maintained their weight for a few months and not have serious heart issues or other specific health conditions. However, it’s important that they haven’t recently used any weight loss medications or insulin.
Recruiting
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
PHASE2 Birmingham, Alabama +4 sites NCT07668388
This trial is looking for people with type 2 diabetes to test a new medicine called UBT251. Participants will receive either UBT251, a placebo, or another medication called semaglutide, chosen at random.
Recruiting
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
PHASE2 Birmingham, Alabama +4 sites NCT07340320
This trial is looking for adults with type 2 diabetes who aren't able to control their blood sugar well while taking metformin. Participants will receive either the new medication CX11 or a placebo for 24 weeks, followed by a 2-week follow-up.
Recruiting
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
PHASE1 Tucson, Arizona +4 sites NCT06783309
This trial is looking for teenagers and young adults aged 12-35 who have been diagnosed with Type 1 Diabetes in the last 6 months. Participants will take a study medication called CNP-103 and will be monitored for safety and effectiveness over about a year.
Recruiting
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
PHASE2 San Francisco, California +4 sites NCT07142252
This trial is looking for people recently diagnosed with type 1 diabetes. Participants will take either the study drug or a placebo every two weeks for 26 weeks, followed by a 6-month check-up.
Recruiting
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
PHASE2 Indianapolis, Indiana NCT05414409
This trial is looking for young people aged 11-18 with Type 1 Diabetes who are overweight, obese, or lean. Participants will help researchers understand the role of gut bacteria in Type 1 Diabetes and how a diabetes medication called metformin might work.
Recruiting
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
PHASE2 Los Angeles, California +4 sites NCT07224321
This trial is looking for young people aged 6 to under 18 with newly diagnosed type 1 diabetes. Participants will take a medication called Afrezza along with another insulin for 13 weeks, with a possible option to continue for another 26 weeks.
Recruiting
See all 42 Diabetes trials in Indiana

Where the Diabetes studies are in Indiana

Research sites running the most studies
  • Indiana University, Indianapolis10 trials
  • Indiana University School of Medicine, Indianapolis2 trials
  • Research Site, Evansville2 trials
  • AES - DRS - Synexus Clinical Research US, Inc. - Evansville, Evansville1 trial
  • AURORA-2 Clinical Site, Evansville1 trial
  • AURORA-2 Clinical Site, Indianapolis1 trial
By city

Counts are recruiting studies listing at least one site in Indiana, from ClinicalTrials.gov, refreshed every two days.

Diabetes clinical trials in Indiana: common questions

How many Diabetes clinical trials are recruiting in Indiana?
TrialFinder currently lists 42 recruiting Diabetes clinical trials with study sites in Indiana. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Diabetes clinical trials located in Indiana?
Study sites for the Diabetes trials listed on this page include Indianapolis. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Diabetes clinical trial in Indiana?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Diabetes trials in Indiana also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Diabetes clinical trial in Indiana?
Each study sets its own criteria based on age, Diabetes diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a diabetes clinical trial if I am already on medication?
Usually yes. Most type 2 diabetes trials enroll people on metformin or other oral medicines and test a new treatment on top of them; some require a stable dose for a few months first. Trials that exclude insulin or a specific drug say so in their criteria.
Do I need to know my A1c to apply?
No. Trials state an A1c range, but the study site measures it at the screening visit. You only need to know that you have been diagnosed and which type.
Diabetes Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Diabetes Trials

Diabetes clinical trials study new treatments for Type 1, Type 2, and gestational diabetes, including insulin therapies, diet interventions, and islet-cell transplants.

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