20 Recruiting Trials
Clinical Trials
for Hypertension in Indiana
20 clinical trials for Hypertension are currently recruiting participants at study sites in Indiana. Study-related care is provided at no cost.
20
Recruiting trials
33
Study sites
14
Cities
12
Industry-sponsored
2
Phase 2
5
Phase 3
Hypertension clinical trials in Indiana: what to expect
High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.
In Indiana, recruiting hypertension studies are concentrated in Indianapolis, Bloomington, Avon and Evansville, with sites in 10 other cities. 12 of the 20 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who hypertension trials usually look for
Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.
What taking part involves
Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.
Questions worth asking the study team
Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.
Showing 20 of 20 recruiting Hypertension trials in Indiana
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Recruiting
This trial is looking for adults with high blood pressure in the lungs caused by lung disease. Participants will take either L606 or a placebo for comparison while doctors monitor their health and side effects.
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Recruiting
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Recruiting
This trial is looking for adults with high blood pressure that is hard to control. Participants will take either the drug RTN-001 or a placebo (a dummy pill) every day for 12 weeks and visit the clinic for checkups.
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Recruiting
This trial is looking for adults who are at least 18 years old and have been diagnosed with a specific lung disease. They need to have a certain level of lung function that is low enough, but they can't already have been diagnosed with high blood pressure in the lungs or have certain heart conditions. It's also important that they haven't had a specific heart test in the last year and are generally healthy enough to participate.
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
Recruiting
This trial is looking for adults with pulmonary hypertension and issues with heart function. Participants will be assessed for safety and effectiveness of a specific treatment device.
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Recruiting
This trial is looking for adults with pulmonary hypertension related to interstitial lung disease. Participants will share information about their health and treatments to help improve understanding of these conditions.
An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
Recruiting
This trial is looking for people with pulmonary hypertension related to interstitial lung disease. Participants will take part in a treatment involving inhaled medication and undergo assessments to monitor their health.
Pulmonary Hypertension Association Registry
Recruiting
This trial is looking for people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). Participants will provide information about their health and treatment to help improve care for these conditions.
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Recruiting
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Recruiting
This trial is looking for adults with high blood pressure that is not well controlled and have either a history of heart disease or are at high risk for heart disease. Participants will receive either the study drug, zilebesiran, or a placebo to see if it lowers the risk of serious heart-related events.
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Recruiting
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension
Recruiting
This trial is looking for adults with high blood pressure and food insecurity. Participants will receive help with food and cooking skills, and their health will be monitored throughout the program.
Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension
Recruiting
This trial is looking for adults with glaucoma or high eye pressure. Participants will receive either netarsudil eye drops or a placebo and will undergo eye imaging tests over about two weeks.
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Recruiting
This trial is looking for adults with high levels of inflammation and increased risk for heart issues. Participants will take clazakizumab or a placebo for about 9 months to see how it affects inflammation levels in the body.
Ketone Ester and Salt (KEAS) in Young Adults
Recruiting
This trial is looking for young adults who want to help researchers understand if ketone supplements can protect against the effects of a high salt diet. Participants will consume a high salt diet and take ketone supplements for a short period.
Ketone Ester And Salt (KEAS) in Older Adults
Recruiting
This trial is looking for older adults who may be affected by high dietary salt. Participants will explore the effects of ketone supplements on blood pressure and overall health.
MIND Foods and Aerobic Training in Black Adults With HTN
Recruiting
This trial is looking for Black adults aged 35-75 with high blood pressure. Participants will follow a special diet and exercise program, and undergo various health assessments over the study period.
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Recruiting
This trial is looking for adults who have high blood pressure after a stroke. Participants will receive either clevidipine or another treatment to help manage their blood pressure within 60 minutes.
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
This trial is looking for patients with advanced heart failure who are not dependent on intravenous medications. Participants will be evaluated to see if a device called HeartMate 3 can help their heart function better compared to standard medical treatments.
Where the Hypertension studies are in Indiana
Research sites running the most studies
- Eskenazi Health, Indianapolis2 trials
- American Health Network - Avon, Avon1 trial
- American Health Network - Franklin, Franklin1 trial
- American Health Network - Greenfield, Greenfield1 trial
- American Health Network - Muncie, Muncie1 trial
- Ascension St. Vincent, Indianapolis1 trial
By city
Counts are recruiting studies listing at least one site in Indiana, from ClinicalTrials.gov, refreshed every two days.
Hypertension clinical trials in Indiana: common questions
How many Hypertension clinical trials are recruiting in Indiana?
TrialFinder currently lists 20 recruiting Hypertension clinical trials with study sites in Indiana. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Indiana?
Study sites for the Hypertension trials listed on this page include Indianapolis, Bloomington. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Indiana?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Indiana also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Indiana?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
Hypertension Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Hypertension Trials
Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.
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