38 Recruiting Trials

Clinical Trials
for Hypertension in New York

38 clinical trials for Hypertension are currently recruiting participants at study sites in New York. Study-related care is provided at no cost.

38
Recruiting trials
80
Study sites
24
Cities
25
Industry-sponsored
5
Phase 2
12
Phase 3

Hypertension clinical trials in New York: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In New York, recruiting hypertension studies are concentrated in New York, Rochester, Buffalo and The Bronx, with sites in 20 other cities. 25 of the 38 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 20 of 38 recruiting Hypertension trials in New York

Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
PHASE2 Arvada, Colorado +4 sites NCT07511361
This trial is looking for adults who have recently been hospitalized for severe high blood pressure. Participants will take a medication called tonlamarsen to see how well it lowers their blood pressure.
Recruiting
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
PHASE2 Phoenix, Arizona +4 sites NCT07090161
This trial is looking for people with uncontrolled high blood pressure. Participants will take either the study drug or a placebo to see if it helps lower their blood pressure.
Recruiting
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
NA Tucson, Arizona +4 sites NCT07214376
This trial is looking for patients with heart failure and pulmonary hypertension. Participants will receive a specific treatment and be monitored for three years to evaluate safety and effectiveness.
Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NA Birmingham, Alabama +4 sites NCT06559891
This trial is looking for adults with hypertension who have not been able to control their blood pressure with medication. Participants will stop taking their blood pressure medications for a short time and receive either the TIVUS treatment or a sham procedure.
Recruiting
Partners in Control, Phase II: Using Remote Monitoring Technology With Community Health Workers to Support Hypertension Management for Latinx Patients
NA New York, New York NCT06730230
This trial is looking for Latinx adults who have high blood pressure that is not well controlled. Participants will use remote monitoring technology with the help of community health workers to manage their condition.
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
PHASE3 Phoenix, Arizona +4 sites NCT07285655
This trial is looking for adults with high blood pressure in the lungs caused by lung disease. Participants will take either L606 or a placebo for comparison while doctors monitor their health and side effects.
Recruiting
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
PHASE3 Fresno, California +4 sites NCT06274801
This trial is looking for adults who have completed a previous study with seralutinib. Participants will take seralutinib and be monitored for safety and effectiveness over time.
Recruiting
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
PHASE3 Phoenix, Arizona +4 sites NCT07179380
This trial is looking for adults with pulmonary hypertension linked to interstitial lung disease. Participants will take either a study drug called TPIP or a placebo once a day for 24 weeks and will be monitored for their exercise ability.
Recruiting
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
PHASE3 Los Angeles, California +4 sites NCT07481981
This trial is looking for adults with pulmonary arterial hypertension (PAH) who want to try a new inhalation treatment. Participants will take the treatment once a day for 24 weeks and will be monitored for changes in their exercise ability.
Recruiting
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
PHASE3 Phoenix, Arizona +4 sites NCT07218029
This trial is looking for people who have completed a previous study with sotatercept for pulmonary arterial hypertension (PAH). Participants will be monitored for the long-term safety and tolerance of sotatercept along with their usual PAH treatments.
Recruiting
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
PHASE3 Scottsdale, Arizona +4 sites NCT07365332
This trial is looking for adults with a specific type of high blood pressure in the lungs called pulmonary arterial hypertension (PAH). Participants will take IKT-001 and be monitored for its effectiveness and safety.
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
PHASE3 Alexander City, Alabama +4 sites NCT07288398
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
Recruiting
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
PHASE2 Alexander City, Alabama +4 sites NCT07142356
This trial is looking for adults with high blood pressure that is hard to control. Participants will take either the drug RTN-001 or a placebo (a dummy pill) every day for 12 weeks and visit the clinic for checkups.
Recruiting
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
PHASE2 Little Rock, Arkansas +4 sites NCT06343298
This trial is looking for adults aged 18 to 80 who have high blood pressure that is hard to manage. Participants will receive either a treatment called MANP or a placebo to see if it helps lower their blood pressure.
Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NA Birmingham, Alabama +4 sites NCT06911632
This trial is looking for adults who are at least 18 years old and have been diagnosed with a specific lung disease. They need to have a certain level of lung function that is low enough, but they can't already have been diagnosed with high blood pressure in the lungs or have certain heart conditions. It's also important that they haven't had a specific heart test in the last year and are generally healthy enough to participate.
Recruiting
The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease
NA Rochester, New York NCT07561034
This trial is looking for adults with pulmonary hypertension related to interstitial lung disease. Participants will follow a structured exercise program at home for 16 weeks and complete check-ins to see how they are doing.
Recruiting
Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum Hypertension
NA New York, New York +2 sites NCT07209254
This trial is looking for women who have high blood pressure after childbirth. Participants will help compare two different ways to manage their blood pressure through mobile health tools.
Recruiting
Innovative Approaches to Hypertension Management in High-Risk Emergency Department Populations
NA New York, New York NCT07539597
This trial is looking for adults with high blood pressure who visit the emergency department. Participants will answer questions about their health and receive help connecting to local services for their needs.
Recruiting
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
NA La Jolla, California +4 sites NCT04555161
This trial is looking for adults with pulmonary hypertension and issues with heart function. Participants will be assessed for safety and effectiveness of a specific treatment device.
Recruiting
Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
NA Buffalo, New York +2 sites NCT05884190
This trial is looking for women who have recently given birth and may experience high blood pressure after delivery. Participants will receive different care approaches to help detect and manage postpartum hypertension and related health issues.
Recruiting

Where the Hypertension studies are in New York

  • NYU Langone Health, New York5 trials
  • University of Rochester Medical Center, Rochester5 trials
  • Icahn School of Medicine at Mount Sinai, New York3 trials
  • Albany Medical Center, Albany2 trials
  • North Shore University Hospital, Manhasset2 trials
  • Weill Cornell Medical Center, New York2 trials

Counts are recruiting studies listing at least one site in New York, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in New York: common questions

How many Hypertension clinical trials are recruiting in New York?
TrialFinder currently lists 38 recruiting Hypertension clinical trials with study sites in New York. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in New York?
Study sites for the Hypertension trials listed on this page include New York, Rochester, Buffalo. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in New York?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in New York also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in New York?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
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Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

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