Multiple Sclerosis Trials / Trials in New York
23 Recruiting Trials

Clinical Trials
for Multiple Sclerosis in New York

23 clinical trials for Multiple Sclerosis are currently recruiting participants at study sites in New York. Study-related care is provided at no cost.

23
Recruiting trials
26
Study sites
5
Cities
9
Industry-sponsored
5
Phase 2
4
Phase 3

Multiple Sclerosis clinical trials in New York: what to expect

Multiple sclerosis trials divide into relapsing and progressive forms. Relapsing MS studies test new oral and infused disease-modifying therapies, usually against an approved medicine rather than a placebo. Progressive MS has fewer approved options, so trials there test drugs meant to slow disability, protect nerves or repair myelin, and often do use a placebo. Alongside these are trials of rehabilitation, exercise, diet, fatigue and bladder treatments, and studies that simply follow people over time with MRI and blood tests.

In New York, recruiting multiple sclerosis studies are concentrated in New York, Buffalo, Rochester and Amherst, with sites in 1 other city. 9 of the 23 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who multiple sclerosis trials usually look for

Listings state the type of MS, an age range (commonly 18 to 55 for relapsing trials, up to 65 for progressive) and a disability score range measured by the study neurologist. Relapsing trials usually want a relapse or new MRI activity in the past one to two years. Drug trials require a washout from your current therapy, which varies from weeks to months by drug and is managed by the site. Symptom and rehabilitation trials let you stay on your treatment.

What taking part involves

Screening includes a neurological exam, blood work and an MRI. Drug trials then run one to three years with visits every one to three months, an MRI every six to twelve months and a relapse assessment whenever symptoms change. Relapses are treated as normal. The study drug, scans and visits are free, and an extension usually lets everyone continue the active treatment afterwards. Rehabilitation trials involve sessions over eight to twenty-four weeks with walking, hand and cognition tests.

Questions worth asking the study team

What the comparison treatment is; how the washout from your current therapy is handled and how long it lasts; how many MRIs are needed; whether there is an extension; and what happens if you relapse during the study.

Showing 20 of 23 recruiting Multiple Sclerosis trials in New York

Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
PHASE1 New York, New York +4 sites NCT07477639
This trial is looking for adults with two types of Multiple Sclerosis called primary progressive or secondary progressive MS. Participants will receive a treatment called TRX319 and will undergo tests to check the treatment's safety and effectiveness over about a year.
Recruiting
Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis
PHASE2 New York, New York +1 sites NCT07497399
This trial is looking for adults with Multiple Sclerosis who are stable on treatment. Participants will take either the study drug or a placebo to help see if it can reduce brain and eye damage.
Recruiting
Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)
PHASE2 New York, New York NCT06901687
This trial is looking for people with multiple sclerosis who are also experiencing depression. Participants will use a device at home for 30 minutes each day, while listening to mindfulness meditation, for 30 days.
Recruiting
Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)
PHASE2 Buffalo, New York NCT06463743
This trial is looking for older adults with multiple sclerosis (MS) to test metformin. Participants will take metformin or a placebo for 9 months while doctors check their health using MRI scans.
Recruiting
Vancomycin Study in Multiple Sclerosis (MS)
PHASE1 New York, New York NCT05539729
This trial is looking for people aged 18 to 50 who have recently been diagnosed with multiple sclerosis and are treatment naive. Participants will take vancomycin to see how it impacts their gut health and brain MRI results.
Recruiting
An Open-label Study of AZD0120 in Adults With Multiple Sclerosis
PHASE1 New York, New York +4 sites NCT07224373
This trial is looking for adults with multiple sclerosis to test a new treatment called AZD0120. Participants will need to provide consent and meet specific health criteria to join the study.
Recruiting
A Study of the MIND Diet for Persons With Multiple Sclerosis
NA New York, New York NCT06992115
This trial is looking for people with multiple sclerosis to see how the MIND diet affects their health. Participants will either follow the MIND diet for a year or continue with their current diet while receiving support.
Recruiting
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
N/A Birmingham, Alabama +4 sites NCT06433752
This trial is looking for people with a confirmed diagnosis of relapsing multiple sclerosis who are starting treatment with BRIUMVI®. Participants will receive the medication and share their experiences and results during the study.
Recruiting
Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
N/A New York, New York NCT05982925
This trial is looking for individuals with multiple sclerosis or similar autoimmune conditions. Participants will undergo evaluations and tests at the start and again at years 1, 3, and 6.
Recruiting
Genes and Environment in Multiple Sclerosis
N/A New York, New York +4 sites NCT01353547
This trial is looking for people who might be at risk for multiple sclerosis due to genetics or other factors. Participants will help researchers understand these risks better, which could lead to ways to prevent or treat the disease.
Recruiting
Eccentric Exercise and Fatigue in Multiple Sclerosis
N/A New York, New York NCT06505421
This trial is looking for people with multiple sclerosis (MS) to see how different types of exercise affect fatigue. Participants will try two types of resistance training over two weeks and report their fatigue levels.
Recruiting
Effect of Cooling on Balance Performance in Multiple Sclerosis
N/A New York, New York NCT06094855
This trial is looking for people with Multiple Sclerosis to see if wearing a cooling vest can improve balance. Participants will take a balance test and then pedal on a stationary bike while wearing the vest or without it to compare results.
Recruiting
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
PHASE3 Palo Alto, California +4 sites NCT04047628
This trial is looking for adults with treatment-resistant multiple sclerosis. Participants will be randomly assigned to receive either stem cell transplantation or the best available therapy and will be followed for 6 years.
Recruiting
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
PHASE3 Scottsdale, Arizona +4 sites NCT06846281
This trial is looking for people with relapsing multiple sclerosis who have been treated with ocrelizumab and want to switch to remibrutinib. Participants will take remibrutinib and their health will be monitored.
Recruiting
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
PHASE3 Phoenix, Arizona +4 sites NCT07299019
This trial is looking for people with Secondary Progressive Multiple Sclerosis who have not had a clinical relapse for at least 2 years. Participants will receive either orelabrutinib or a placebo for 1 to 5 years.
Recruiting
A Palliative Care Model Impact on Knowledge and Attitudes
NA New York, New York +1 sites NCT06860932
Recruiting
Prepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS?
NA Buffalo, New York +2 sites NCT07225868
This trial is looking for people with Multiple Sclerosis who experience memory and concentration issues. Participants will use an app-based training program for 12 weeks followed by a 6-week cognitive rehabilitation program.
Recruiting
Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab
PHASE3 Birmingham, Alabama +4 sites NCT05877963
This trial is looking for people with relapsing multiple sclerosis. Participants will receive a modified treatment of ublituximab and help researchers understand its effectiveness and safety.
Recruiting
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
PHASE2 Birmingham, Alabama +4 sites NCT07002034
This trial is looking for people who have been diagnosed with Adjustment Disorder due to cancer or certain other health conditions. Participants will receive a single dose of the study drug to see if it helps reduce their depressive or anxiety symptoms.
Recruiting
Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment
PHASE1 New York, New York +4 sites NCT07304154
This trial is looking for people with conditions like multiple sclerosis, myasthenia gravis, or chronic inflammatory demyelinating polyneuropathy. Participants will help researchers understand the safety and effectiveness of a new treatment called KITE-363.
Recruiting
See all 23 Multiple Sclerosis trials in New York

Where the Multiple Sclerosis studies are in New York

Research sites running the most studies
  • TG Therapeutics Investigational Trial Site, New York3 trials
  • Hunter College, Physical Therapy Department, City University of New York, New York2 trials
  • Mount Sinai Hospital, New York2 trials
  • NYU Langone Health, New York2 trials
  • Columbia University Irving Center, New York1 trial
  • Columbia University Irving Medical Center, New York1 trial
By city

Counts are recruiting studies listing at least one site in New York, from ClinicalTrials.gov, refreshed every two days.

Multiple Sclerosis clinical trials in New York: common questions

How many Multiple Sclerosis clinical trials are recruiting in New York?
TrialFinder currently lists 23 recruiting Multiple Sclerosis clinical trials with study sites in New York. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Multiple Sclerosis clinical trials located in New York?
Study sites for the Multiple Sclerosis trials listed on this page include New York, Buffalo. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Multiple Sclerosis clinical trial in New York?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Multiple Sclerosis trials in New York also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Multiple Sclerosis clinical trial in New York?
Each study sets its own criteria based on age, Multiple Sclerosis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of MS treatment?
In relapsing MS almost never: trials compare the new drug with an approved medicine, so everyone is treated. Progressive MS trials more often use a placebo because fewer approved treatments exist, and an extension usually follows.
Do I need to stop my current MS medicine to join?
For a drug trial, yes, after a washout that depends on your current medicine and is supervised by the study neurologist. Trials of rehabilitation, diet or symptom treatments let you continue it.
What is an EDSS score?
The Expanded Disability Status Scale, a 0 to 10 score a neurologist assigns from an exam, mostly based on walking. Trials set a range, and the study neurologist scores you at screening; you do not need to know it in advance.
Multiple Sclerosis Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Multiple Sclerosis trials near you in New York.

Get Matched — Free
No insurance required
About Multiple Sclerosis Trials

MS trials investigate disease-modifying therapies, remyelination strategies, stem-cell transplants, and neuroprotective agents for relapsing and progressive forms of MS.

All Multiple Sclerosis trials →
Other Conditions in New York
Diabetes Cancer Breast Cancer Depression Anxiety Alzheimer's Heart Disease Asthma Obesity Parkinson's Lupus Hypertension COPD Stroke Arthritis Kidney Disease COVID-19
All trials in New York →