MRI and CSF Analysis for Multiple Sclerosis and Related Conditions
Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
Recruiting
Observational Study
Multiple Sclerosis
Neuromyelitis Optica
Demyelinating Autoimmune Diseases, CNS
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 170 (estimated)
- Sponsor
- Icahn School of Medicine at Mount Sinai · Other
Who this trial is looking for
This trial is looking for individuals with multiple sclerosis or similar autoimmune conditions. Participants will undergo evaluations and tests at the start and again at years 1, 3, and 6.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I can provide consent in English
- I am able to undergo an MRI
You may not be able to join if
- I have a condition that makes MRI unsafe for me
- I am currently pregnant
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclerosis (MS) and other inflammatory and autoimmune disorders affecting the CNS. Patients with these diso…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18 years old
* able to provide consent in English
* able to undergo MRI
Exclusion Criteria:
* contraindication to MRI
* pregnancy
Contacts