22 Recruiting Trials
Clinical Trials
for Multiple Sclerosis in Texas
22 clinical trials for Multiple Sclerosis are currently recruiting participants at study sites in Texas. Study-related care is provided at no cost.
22
Recruiting trials
41
Study sites
13
Cities
12
Industry-sponsored
3
Phase 2
8
Phase 3
Multiple Sclerosis clinical trials in Texas: what to expect
Multiple sclerosis trials divide into relapsing and progressive forms. Relapsing MS studies test new oral and infused disease-modifying therapies, usually against an approved medicine rather than a placebo. Progressive MS has fewer approved options, so trials there test drugs meant to slow disability, protect nerves or repair myelin, and often do use a placebo. Alongside these are trials of rehabilitation, exercise, diet, fatigue and bladder treatments, and studies that simply follow people over time with MRI and blood tests.
In Texas, recruiting multiple sclerosis studies are concentrated in Houston, Austin, Dallas and Plano, with sites in 9 other cities. 12 of the 22 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who multiple sclerosis trials usually look for
Listings state the type of MS, an age range (commonly 18 to 55 for relapsing trials, up to 65 for progressive) and a disability score range measured by the study neurologist. Relapsing trials usually want a relapse or new MRI activity in the past one to two years. Drug trials require a washout from your current therapy, which varies from weeks to months by drug and is managed by the site. Symptom and rehabilitation trials let you stay on your treatment.
What taking part involves
Screening includes a neurological exam, blood work and an MRI. Drug trials then run one to three years with visits every one to three months, an MRI every six to twelve months and a relapse assessment whenever symptoms change. Relapses are treated as normal. The study drug, scans and visits are free, and an extension usually lets everyone continue the active treatment afterwards. Rehabilitation trials involve sessions over eight to twenty-four weeks with walking, hand and cognition tests.
Questions worth asking the study team
What the comparison treatment is; how the washout from your current therapy is handled and how long it lasts; how many MRIs are needed; whether there is an extension; and what happens if you relapse during the study.
Showing 20 of 22 recruiting Multiple Sclerosis trials in Texas
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
Recruiting
This trial is looking for adults aged 18-65 with secondary progressive multiple sclerosis (SPMS). Participants will take the medication remibrutinib and have regular assessments to evaluate its effects.
Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
Recruiting
This trial is looking for adults between 18 to 60 years old with Multiple Sclerosis. Participants will receive frexalimab either by injection under the skin or through an IV every four weeks for a year.
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
Recruiting
This trial is looking for children and adolescents with relapsing remitting multiple sclerosis (MS). Participants will take either ozanimod or fingolimod and help researchers understand how well these treatments work and their effects on the body.
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
Recruiting
This trial is looking for people with multiple sclerosis (MS) who experience muscle stiffness for at least 6 months. Participants will help evaluate the safety and effectiveness of a new treatment.
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
Recruiting
This trial is looking for people aged 18 to 55 with multiple sclerosis. Participants will receive either the study drug, mRNA-1195, or a placebo while being monitored for safety and side effects.
Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple Sclerosis
Recruiting
This trial is looking for Hispanic or Latino individuals diagnosed with multiple sclerosis. Participants will engage in a 16-week exercise program to help improve walking ability.
Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation
Recruiting
This trial is looking for people with relapsing-remitting multiple sclerosis who have trouble remembering things. Participants will receive low-level electrical stimulation to see if it helps improve their memory.
Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study
Recruiting
This trial is looking for people with multiple sclerosis who have memory or thinking problems. Participants will take part in a 12-week music program to help with their cognitive and emotional health.
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
Recruiting
This trial is looking for people with a confirmed diagnosis of relapsing multiple sclerosis who are starting treatment with BRIUMVI®. Participants will receive the medication and share their experiences and results during the study.
Care in Multiple Sclerosis (MS)
Recruiting
This trial is looking for individuals with relapsing-remitting multiple sclerosis, particularly from Black, Hispanic, or low-income backgrounds. Participants will take part in interviews and assessments to understand how childhood experiences and environment affect their health and quality of life.
Multiple Sclerosis Implementation Network (Registry)
Recruiting
This trial is looking for people who have been diagnosed with Multiple Sclerosis (MS) and can speak and understand English comfortably. Participants will help improve MS care and quality of life by contributing to a database that collects their health information.
NARCOMS Registry: A Multiple Sclerosis Registry
Recruiting
This trial is looking for individuals diagnosed with multiple sclerosis or clinically isolated syndrome. Participants will complete a survey online to join and provide updates twice a year, which takes less than 20 minutes each time.
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
Recruiting
This trial is looking for adults with treatment-resistant multiple sclerosis. Participants will be randomly assigned to receive either stem cell transplantation or the best available therapy and will be followed for 6 years.
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Recruiting
This trial is looking for people with relapsing multiple sclerosis who have been treated with ocrelizumab and want to switch to remibrutinib. Participants will take remibrutinib and their health will be monitored.
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
Recruiting
This trial is looking for people with Secondary Progressive Multiple Sclerosis who have not had a clinical relapse for at least 2 years. Participants will receive either orelabrutinib or a placebo for 1 to 5 years.
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Recruiting
This trial is looking for people with Primary Progressive Multiple Sclerosis (PPMS). Participants will take either the study drug orelabrutinib or a placebo for about 30 to 60 months, with at least 12 months of treatment.
The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study
Recruiting
This trial is looking for adults with relapsing-remitting multiple sclerosis (RRMS) to test a new device. Participants will have a small device placed under their skin in a procedure to see if it helps with their condition.
Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab
Recruiting
This trial is looking for people with relapsing multiple sclerosis. Participants will receive a modified treatment of ublituximab and help researchers understand its effectiveness and safety.
Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS
Recruiting
This trial is looking for adult women with multiple sclerosis and overactive bladder symptoms. Participants will receive noninvasive brain stimulation to see if it helps improve their bladder function.
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Recruiting
This trial is looking for people who have been diagnosed with Adjustment Disorder due to cancer or certain other health conditions. Participants will receive a single dose of the study drug to see if it helps reduce their depressive or anxiety symptoms.
Where the Multiple Sclerosis studies are in Texas
Research sites running the most studies
- The University of Texas at Austin, Austin3 trials
- Lone Star Neurology, San Antonio2 trials
- The University of Texas Health Science Center at Houston, Houston2 trials
- ANESC Research, El Paso1 trial
- ANESC Research- Site Number : 8400187, El Paso1 trial
- Austin Regional Clinic, Austin1 trial
By city
Counts are recruiting studies listing at least one site in Texas, from ClinicalTrials.gov, refreshed every two days.
Multiple Sclerosis clinical trials in Texas: common questions
How many Multiple Sclerosis clinical trials are recruiting in Texas?
TrialFinder currently lists 22 recruiting Multiple Sclerosis clinical trials with study sites in Texas. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Multiple Sclerosis clinical trials located in Texas?
Study sites for the Multiple Sclerosis trials listed on this page include Houston, Richardson, Austin, Dallas. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Multiple Sclerosis clinical trial in Texas?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Multiple Sclerosis trials in Texas also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Multiple Sclerosis clinical trial in Texas?
Each study sets its own criteria based on age, Multiple Sclerosis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of MS treatment?
In relapsing MS almost never: trials compare the new drug with an approved medicine, so everyone is treated. Progressive MS trials more often use a placebo because fewer approved treatments exist, and an extension usually follows.
Do I need to stop my current MS medicine to join?
For a drug trial, yes, after a washout that depends on your current medicine and is supervised by the study neurologist. Trials of rehabilitation, diet or symptom treatments let you continue it.
What is an EDSS score?
The Expanded Disability Status Scale, a 0 to 10 score a neurologist assigns from an exam, mostly based on walking. Trials set a range, and the study neurologist scores you at screening; you do not need to know it in advance.
Multiple Sclerosis Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Multiple Sclerosis Trials
MS trials investigate disease-modifying therapies, remyelination strategies, stem-cell transplants, and neuroprotective agents for relapsing and progressive forms of MS.
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