14 Recruiting Trials

Clinical Trials
for Multiple Sclerosis in New Jersey

14 clinical trials for Multiple Sclerosis are currently recruiting participants at study sites in New Jersey. Study-related care is provided at no cost.

14
Recruiting trials
19
Study sites
12
Cities
7
Industry-sponsored
4
Phase 3

Multiple Sclerosis clinical trials in New Jersey: what to expect

Multiple sclerosis trials divide into relapsing and progressive forms. Relapsing MS studies test new oral and infused disease-modifying therapies, usually against an approved medicine rather than a placebo. Progressive MS has fewer approved options, so trials there test drugs meant to slow disability, protect nerves or repair myelin, and often do use a placebo. Alongside these are trials of rehabilitation, exercise, diet, fatigue and bladder treatments, and studies that simply follow people over time with MRI and blood tests.

In New Jersey, recruiting multiple sclerosis studies are concentrated in Teaneck, East Hanover, Cherry Hill and Livingston, with sites in 8 other cities. 7 of the 14 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who multiple sclerosis trials usually look for

Listings state the type of MS, an age range (commonly 18 to 55 for relapsing trials, up to 65 for progressive) and a disability score range measured by the study neurologist. Relapsing trials usually want a relapse or new MRI activity in the past one to two years. Drug trials require a washout from your current therapy, which varies from weeks to months by drug and is managed by the site. Symptom and rehabilitation trials let you stay on your treatment.

What taking part involves

Screening includes a neurological exam, blood work and an MRI. Drug trials then run one to three years with visits every one to three months, an MRI every six to twelve months and a relapse assessment whenever symptoms change. Relapses are treated as normal. The study drug, scans and visits are free, and an extension usually lets everyone continue the active treatment afterwards. Rehabilitation trials involve sessions over eight to twenty-four weeks with walking, hand and cognition tests.

Questions worth asking the study team

What the comparison treatment is; how the washout from your current therapy is handled and how long it lasts; how many MRIs are needed; whether there is an extension; and what happens if you relapse during the study.

Showing 14 of 14 recruiting Multiple Sclerosis trials in New Jersey

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
PHASE3 Cullman, Alabama +4 sites NCT07325292
This trial is looking for adults between 18 to 60 years old with Multiple Sclerosis. Participants will receive frexalimab either by injection under the skin or through an IV every four weeks for a year.
Recruiting
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
PHASE3 Loma Linda, California +4 sites NCT06408259
This trial is looking for children and adolescents with relapsing remitting multiple sclerosis (MS). Participants will take either ozanimod or fingolimod and help researchers understand how well these treatments work and their effects on the body.
Recruiting
Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis
PHASE4 Morristown, New Jersey NCT07614321
This trial is looking for women with multiple sclerosis who have problems with their urinary tract. Participants will take either silodosin or a placebo every day for 8 weeks and visit the clinic to answer questions and undergo tests.
Recruiting
A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis
NA East Hanover, New Jersey NCT06197685
This trial is looking for people with multiple sclerosis who have difficulty with mobility. Participants will engage in a combined program of cognitive rehabilitation and exercise to improve learning and memory.
Recruiting
Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community
NA East Hanover, New Jersey NCT06608797
This trial is looking for people with multiple sclerosis who struggle with learning and memory. Participants will engage in 10 sessions of computer-based cognitive training conducted over Zoom.
Recruiting
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
N/A Birmingham, Alabama +4 sites NCT06433752
This trial is looking for people with a confirmed diagnosis of relapsing multiple sclerosis who are starting treatment with BRIUMVI®. Participants will receive the medication and share their experiences and results during the study.
Recruiting
Risk of Progressive Multifocal Leukoencephalopathy Among Patients With Multiple Sclerosis Exposed to Zeposia
N/A Lawrenceville, New Jersey NCT07732907
This trial is looking for people with multiple sclerosis who have experienced a rare brain infection called PML after using a treatment called ozanimod. Participants will help researchers understand the risk and characteristics of this infection.
Recruiting
Multiple Sclerosis Implementation Network (Registry)
N/A Cherry Hill, New Jersey +2 sites NCT07415824
This trial is looking for people who have been diagnosed with Multiple Sclerosis (MS) and can speak and understand English comfortably. Participants will help improve MS care and quality of life by contributing to a database that collects their health information.
Recruiting
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
PHASE3 Scottsdale, Arizona +4 sites NCT06846281
This trial is looking for people with relapsing multiple sclerosis who have been treated with ocrelizumab and want to switch to remibrutinib. Participants will take remibrutinib and their health will be monitored.
Recruiting
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
PHASE3 Pheonix, Arizona +4 sites NCT07067463
This trial is looking for people with Primary Progressive Multiple Sclerosis (PPMS). Participants will take either the study drug orelabrutinib or a placebo for about 30 to 60 months, with at least 12 months of treatment.
Recruiting
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
NA West Orange, New Jersey NCT04855825
This trial is looking for people with multiple sclerosis who have difficulty walking and thinking. Participants will test a robotic exoskeleton to see if it helps with walking and memory during therapy.
Recruiting
A Study Comparing Effectiveness of Kesimpta® (Ofatumumab) Versus Ocrevus® (Ocrelizumab) in Real-world Practice
N/A East Hanover, New Jersey NCT07779460
This trial is looking for adults diagnosed with multiple sclerosis who are considering treatment with Kesimpta or Ocrevus. Participants will be monitored over time to compare the effectiveness of these two medications.
Recruiting
Gait Adaptation Study
EARLY_PHASE1 Newark, New Jersey NCT07660601
This trial is looking for people with Multiple Sclerosis (MS) who are between 18 and 80 years old. Participants will take part in training to potentially improve their movement and brain connections.
Recruiting
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
PHASE1 Birmingham, Alabama +4 sites NCT03816345
This trial is looking for adults with advanced cancers who also have autoimmune disorders. Participants will receive treatments that may include the drug nivolumab and possibly others to see how well they work together.
Recruiting

Where the Multiple Sclerosis studies are in New Jersey

  • Kessler Foundation, East Hanover2 trials
  • Atlantic Health, Morristown1 trial
  • Bristol Myers Squibb, Lawrenceville1 trial
  • Cooperman Barnabas Medical Center, Livingston1 trial
  • Holy Name Medical Center, Teaneck1 trial
  • Holy Name Medical Center- Site Number : 8400101, Teaneck1 trial

Counts are recruiting studies listing at least one site in New Jersey, from ClinicalTrials.gov, refreshed every two days.

Multiple Sclerosis clinical trials in New Jersey: common questions

How many Multiple Sclerosis clinical trials are recruiting in New Jersey?
TrialFinder currently lists 14 recruiting Multiple Sclerosis clinical trials with study sites in New Jersey. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Multiple Sclerosis clinical trials located in New Jersey?
Study sites for the Multiple Sclerosis trials listed on this page include Morristown, East Hanover, Lawrenceville, Cherry Hill, West Orange, Newark. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Multiple Sclerosis clinical trial in New Jersey?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Multiple Sclerosis trials in New Jersey also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Multiple Sclerosis clinical trial in New Jersey?
Each study sets its own criteria based on age, Multiple Sclerosis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of MS treatment?
In relapsing MS almost never: trials compare the new drug with an approved medicine, so everyone is treated. Progressive MS trials more often use a placebo because fewer approved treatments exist, and an extension usually follows.
Do I need to stop my current MS medicine to join?
For a drug trial, yes, after a washout that depends on your current medicine and is supervised by the study neurologist. Trials of rehabilitation, diet or symptom treatments let you continue it.
What is an EDSS score?
The Expanded Disability Status Scale, a 0 to 10 score a neurologist assigns from an exam, mostly based on walking. Trials set a range, and the study neurologist scores you at screening; you do not need to know it in advance.
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MS trials investigate disease-modifying therapies, remyelination strategies, stem-cell transplants, and neuroprotective agents for relapsing and progressive forms of MS.

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