No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
19 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Kessler Foundation · Other
Who this trial is looking for
This trial is looking for people with multiple sclerosis who struggle with learning and memory. Participants will engage in 10 sessions of computer-based cognitive training conducted over Zoom.
Are You a Good Fit for This Trial?
Rules you outMajor Depressive DisorderSchizophreniaBipolar Disorder IBipolar Disorder II
You may be able to join if
I speak English as my primary language
I have been diagnosed with multiple sclerosis
You may not be able to join if
I have had an MS exacerbation within the past month
I have a history of significant neurological issues like head injury or stroke
I have an active diagnosis of Major Depressive Disorder
I have poor visual acuity or other vision problems
I cannot understand directions or follow commands
I do not have problems with new learning and memory
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Cognitive impairments are common in multiple sclerosis (MS) diagnosed both at the onset and throughout the disease course. Poor cognitive abilities have been associated with poor outcomes such as higher levels of unemployment, poor quality of life, driving difficulties among others. Learning and memory are a common cognitive deficit. This computer-based cognitive training is a 10-session treatment…
Cognitive impairments are common in multiple sclerosis (MS) diagnosed both at the onset and throughout the disease course. Poor cognitive abilities have been associated with poor outcomes such as higher levels of unemployment, poor quality of life, driving difficulties among others. Learning and memory are a common cognitive deficit. This computer-based cognitive training is a 10-session treatment proven to be effective in ameliorating learning and memory in individuals with MS across 3 realms of functioning: objective cognitive performance, daily life activities and neuroimaging. Despite this strong efficacy, as well as the recent clinical application of this computer-based cognitive training across the world, recent in-person studies have highlighted that transportation to the clinic to complete treatment sessions is a significant obstacle to clinical use of this effective treatment. To address this limitation, the proposed pilot study will test the efficacy of the computer-based cognitive training administered remotely via zoom health in persons with multiple sclerosis.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* English as primary language
* Diagnosis of multiple sclerosis
Exclusion Criteria:
* Most recent exacerbation within one month
* Other Neurological History: head injury, stroke, seizures, or any other significant neurological history will not be included in the study
* Indivi…
Inclusion Criteria:
* English as primary language
* Diagnosis of multiple sclerosis
Exclusion Criteria:
* Most recent exacerbation within one month
* Other Neurological History: head injury, stroke, seizures, or any other significant neurological history will not be included in the study
* Individuals with an active diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II will be excluded from the study.
* Poor Visual Acuity (corrected vision in worse eye \< 20/60), diplopia, or nystagmus
* Inability to understand directions and following one, two, and three step commands
* Intact New Learning and Memory: Only individuals that show impaired performance on a memory test will be included in the study
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