Multiple Sclerosis Trials / Trials in District of Columbia
6 Recruiting Trials

Clinical Trials
for Multiple Sclerosis in District of Columbia

6 clinical trials for Multiple Sclerosis are currently recruiting participants at study sites in District of Columbia. Study-related care is provided at no cost.

6
Recruiting trials
6
Study sites
1
City
5
Industry-sponsored
3
Phase 3

Multiple Sclerosis clinical trials in District of Columbia: what to expect

Multiple sclerosis trials divide into relapsing and progressive forms. Relapsing MS studies test new oral and infused disease-modifying therapies, usually against an approved medicine rather than a placebo. Progressive MS has fewer approved options, so trials there test drugs meant to slow disability, protect nerves or repair myelin, and often do use a placebo. Alongside these are trials of rehabilitation, exercise, diet, fatigue and bladder treatments, and studies that simply follow people over time with MRI and blood tests.

In District of Columbia, recruiting multiple sclerosis studies are concentrated in Washington D.C.. 5 of the 6 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who multiple sclerosis trials usually look for

Listings state the type of MS, an age range (commonly 18 to 55 for relapsing trials, up to 65 for progressive) and a disability score range measured by the study neurologist. Relapsing trials usually want a relapse or new MRI activity in the past one to two years. Drug trials require a washout from your current therapy, which varies from weeks to months by drug and is managed by the site. Symptom and rehabilitation trials let you stay on your treatment.

What taking part involves

Screening includes a neurological exam, blood work and an MRI. Drug trials then run one to three years with visits every one to three months, an MRI every six to twelve months and a relapse assessment whenever symptoms change. Relapses are treated as normal. The study drug, scans and visits are free, and an extension usually lets everyone continue the active treatment afterwards. Rehabilitation trials involve sessions over eight to twenty-four weeks with walking, hand and cognition tests.

Questions worth asking the study team

What the comparison treatment is; how the washout from your current therapy is handled and how long it lasts; how many MRIs are needed; whether there is an extension; and what happens if you relapse during the study.

Showing 6 of 6 recruiting Multiple Sclerosis trials in District of Columbia

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
PHASE3 Birmingham, Alabama +4 sites NCT07225504
This trial is looking for adults aged 18-65 with secondary progressive multiple sclerosis (SPMS). Participants will take the medication remibrutinib and have regular assessments to evaluate its effects.
Recruiting
An Open-label Study of AZD0120 in Adults With Multiple Sclerosis
PHASE1 Washington D.C., District of Columbia +4 sites NCT07224373
This trial is looking for adults with multiple sclerosis to test a new treatment called AZD0120. Participants will need to provide consent and meet specific health criteria to join the study.
Recruiting
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
N/A Birmingham, Alabama +4 sites NCT06433752
This trial is looking for people with a confirmed diagnosis of relapsing multiple sclerosis who are starting treatment with BRIUMVI®. Participants will receive the medication and share their experiences and results during the study.
Recruiting
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
PHASE3 Washington D.C., District of Columbia +4 sites NCT06846281
This trial is looking for people with relapsing multiple sclerosis who have been treated with ocrelizumab and want to switch to remibrutinib. Participants will take remibrutinib and their health will be monitored.
Recruiting
Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab
PHASE3 Washington D.C., District of Columbia +4 sites NCT05877963
This trial is looking for people with relapsing multiple sclerosis. Participants will receive a modified treatment of ublituximab and help researchers understand its effectiveness and safety.
Recruiting
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
PHASE1 Birmingham, Alabama +4 sites NCT03816345
This trial is looking for adults with advanced cancers who also have autoimmune disorders. Participants will receive treatments that may include the drug nivolumab and possibly others to see how well they work together.
Recruiting
See all 6 Multiple Sclerosis trials in District of Columbia

Where the Multiple Sclerosis studies are in District of Columbia

Research sites running the most studies
  • TG Therapeutics Investigational Trial Site, Washington D.C.2 trials
  • Georgetown University Hospital, Washington D.C.1 trial
  • MedStar Georgetown University Hospital, Washington D.C.1 trial
  • Medstar Washington Hosp Ctr, Washington D.C.1 trial
  • Medstar Washington Hospital Center, Washington D.C.1 trial
  • Research Site, Washington D.C.1 trial
By city

Counts are recruiting studies listing at least one site in District of Columbia, from ClinicalTrials.gov, refreshed every two days.

Multiple Sclerosis clinical trials in District of Columbia: common questions

How many Multiple Sclerosis clinical trials are recruiting in District of Columbia?
TrialFinder currently lists 6 recruiting Multiple Sclerosis clinical trials with study sites in District of Columbia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Multiple Sclerosis clinical trials located in District of Columbia?
Study sites for the Multiple Sclerosis trials listed on this page include Washington D.C.. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Multiple Sclerosis clinical trial in District of Columbia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Multiple Sclerosis trials in District of Columbia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Multiple Sclerosis clinical trial in District of Columbia?
Each study sets its own criteria based on age, Multiple Sclerosis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I get a placebo instead of MS treatment?
In relapsing MS almost never: trials compare the new drug with an approved medicine, so everyone is treated. Progressive MS trials more often use a placebo because fewer approved treatments exist, and an extension usually follows.
Do I need to stop my current MS medicine to join?
For a drug trial, yes, after a washout that depends on your current medicine and is supervised by the study neurologist. Trials of rehabilitation, diet or symptom treatments let you continue it.
What is an EDSS score?
The Expanded Disability Status Scale, a 0 to 10 score a neurologist assigns from an exam, mostly based on walking. Trials set a range, and the study neurologist scores you at screening; you do not need to know it in advance.
Multiple Sclerosis Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Multiple Sclerosis Trials

MS trials investigate disease-modifying therapies, remyelination strategies, stem-cell transplants, and neuroprotective agents for relapsing and progressive forms of MS.

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Other Conditions in District of Columbia
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