Heart Disease Trials / Trials in District of Columbia
12 Recruiting Trials

Clinical Trials
for Heart Disease in District of Columbia

12 clinical trials for Heart Disease are currently recruiting participants at study sites in District of Columbia. Study-related care is provided at no cost.

12
Recruiting trials
8
Study sites
1
City
7
Industry-sponsored
1
Phase 2
2
Phase 3

Heart Disease clinical trials in District of Columbia: what to expect

Heart disease trials cover heart failure, coronary artery disease, atrial fibrillation, high cholesterol and lipoprotein(a), and the devices and procedures used to treat them. The largest are outcomes trials: thousands of people take a study medicine or placebo on top of their usual treatment for several years while the trial counts heart attacks, strokes and hospital stays. Smaller studies test new heart failure drugs, cholesterol-lowering injections given a few times a year, cardiac rehabilitation programs and monitoring devices.

In District of Columbia, recruiting heart disease studies are concentrated in Washington D.C.. 7 of the 12 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who heart disease trials usually look for

Listings define the condition precisely: an ejection fraction range for heart failure, a heart attack or stent within a recent window, cholesterol still above target on a statin, or a lipoprotein(a) level above a threshold. They usually ask that your current heart medicines have been stable for a month or more. Common exclusions are a very recent procedure, advanced kidney disease and another illness that limits life expectancy. Ages generally run from 18 with no upper limit.

What taking part involves

Screening includes an ECG, blood work and often an echocardiogram. Outcomes trials are long but light: a pill or injection added to your treatment, visits every three to six months and phone check-ins between. Drug trials for heart failure run three to twelve months with monthly visits. Device trials involve a procedure and follow-up imaging. Your existing heart medicines continue throughout; study treatment and tests are free, and travel is usually reimbursed.

Questions worth asking the study team

Whether anything about your current treatment would change; how long the trial runs and how often you must come in; what is being measured and what you will be told about your own results; and whether your cardiologist will receive updates.

Showing 12 of 12 recruiting Heart Disease trials in District of Columbia

Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
N/A Washington D.C., District of Columbia +4 sites NCT04604418
This trial is looking for children and young adults with congenital heart disease who are undergoing non-cardiac procedures. Participants will help researchers understand the risks and healthcare needs for these patients.
Recruiting
Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease
N/A Washington D.C., District of Columbia +2 sites NCT06952933
This trial is looking for adults who have congenital heart disease and want to help researchers learn about the connection between heart health, psychological trauma, and PTSD. Participants will complete surveys online to share their experiences and feelings.
Recruiting
Abbott Structural Heart Device Registry
N/A Washington D.C., District of Columbia +4 sites NCT06590467
This trial is looking for patients who need or have had heart device implants. Participants will help gather information about the safety and performance of specific heart devices used in hospitals.
Recruiting
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
PHASE3 Phoenix, Arizona +4 sites NCT05918211
This trial is looking for adolescents aged 12 to under 19 who have had the Fontan procedure. Participants will take either udenafil or a placebo to help assess its safety and effectiveness.
Recruiting
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
N/A Washington D.C., District of Columbia +1 sites NCT06730113
This trial is looking for young people aged 12 to 25 with type 2 diabetes, those who are overweight, and healthy lean individuals. Participants will attend annual visits at the NIH clinic for up to 25 years and undergo various health tests.
Recruiting
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
N/A Birmingham, Alabama +4 sites NCT02852031
This trial is looking for newborns diagnosed with Hypoplastic Left Heart Syndrome (HLHS) who are meant to have a specific heart surgery called the Norwood procedure. The goal is to gather information to help improve care for these infants.
Recruiting
Cooperative Assessment of Late Effects for SCD Curative Therapies
N/A Washington D.C., District of Columbia +4 sites NCT05153967
This trial is looking for individuals with Sickle Cell Disease (SCD) to study the long-term effects of new treatments. Participants will provide health information before and after treatment to help understand the outcomes.
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
PHASE3 La Jolla, California +4 sites NCT06563895
This trial is looking for adults who carry a specific genetic variant that can lead to a heart condition but have not yet shown any symptoms. Participants will receive an experimental drug called acoramidis to see if it can prevent heart issues.
Recruiting
Transition to KPL-387 Monotherapy Dosing & Administration Study
PHASE2 Washington D.C., District of Columbia +4 sites NCT07288216
This trial is looking for adults who have a recent history of well-controlled recurring chest pain caused by inflammation around the heart. They should have been treated with certain medications for at least three months and currently be stable on those treatments. However, people with certain infections, recent serious illnesses, or specific other health issues are not eligible to join.
Recruiting
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions
NA Washington D.C., District of Columbia +2 sites NCT07258290
This trial is looking for adults between 18 and 80 years old who have certain heart issues that may require treatment, like chest pain or blockages in the arteries. However, they can't be pregnant, have recently experienced a heart attack, or have had heart procedures in the past year. They're hoping to find people who can safely take specific heart medications after the procedure.
Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NA Washington D.C., District of Columbia +4 sites NCT06526195
This trial is looking for patients with advanced heart failure who are not dependent on intravenous medications. Participants will be evaluated to see if a device called HeartMate 3 can help their heart function better compared to standard medical treatments.
Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NA Gilbert, Arizona +4 sites NCT03142152
This trial is looking for individuals with heart failure and a specific type of mitral valve problem. Participants will be randomly assigned to receive either the treatment or a control and will need to attend follow-up visits.
Recruiting
See all 12 Heart Disease trials in District of Columbia

Where the Heart Disease studies are in District of Columbia

Research sites running the most studies
  • Children's National Medical Center, Washington D.C.4 trials
  • MedStar Washington Hospital Center, Washington D.C.2 trials
  • Children's National Hospital (CNH), Washington D.C.1 trial
  • Childrens National Medical Center, Washington D.C.1 trial
  • Investigational Site 046, Washington D.C.1 trial
  • MedStar Washington Hospital Center - MedStar Heart and Vascular Institute, Washington D.C.1 trial
By city

Counts are recruiting studies listing at least one site in District of Columbia, from ClinicalTrials.gov, refreshed every two days.

Heart Disease clinical trials in District of Columbia: common questions

How many Heart Disease clinical trials are recruiting in District of Columbia?
TrialFinder currently lists 12 recruiting Heart Disease clinical trials with study sites in District of Columbia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Heart Disease clinical trials located in District of Columbia?
Study sites for the Heart Disease trials listed on this page include Washington D.C.. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Heart Disease clinical trial in District of Columbia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Heart Disease trials in District of Columbia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Heart Disease clinical trial in District of Columbia?
Each study sets its own criteria based on age, Heart Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I have to stop my heart medicines to join a trial?
Almost never. Heart disease trials add a study treatment to the medicines you already take, and your own cardiologist continues to manage them. A trial that requires a change says so in its listing.
What is a cardiovascular outcomes trial?
A large, multi-year study in which participants take a study medicine or placebo on top of standard care while the trial counts events such as heart attacks and hospital stays. Visits are infrequent, and the drug is provided free throughout.
Can I join a trial after a heart attack or stent?
Yes. Many trials enroll in the weeks after a heart attack or procedure, because that is when the next event is most likely. The window is stated in the listing, so ask soon after discharge.
Heart Disease Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Heart Disease Trials

Cardiovascular trials study statins, PCSK9 inhibitors, heart failure devices, cardiac rehabilitation protocols, and interventional procedures for coronary artery disease.

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