Heart Disease Trials / Trials in Connecticut
8 Recruiting Trials

Clinical Trials
for Heart Disease in Connecticut

8 clinical trials for Heart Disease are currently recruiting participants at study sites in Connecticut. Study-related care is provided at no cost.

8
Recruiting trials
7
Study sites
4
Cities
5
Industry-sponsored
2
Phase 3

Heart Disease clinical trials in Connecticut: what to expect

Heart disease trials cover heart failure, coronary artery disease, atrial fibrillation, high cholesterol and lipoprotein(a), and the devices and procedures used to treat them. The largest are outcomes trials: thousands of people take a study medicine or placebo on top of their usual treatment for several years while the trial counts heart attacks, strokes and hospital stays. Smaller studies test new heart failure drugs, cholesterol-lowering injections given a few times a year, cardiac rehabilitation programs and monitoring devices.

In Connecticut, recruiting heart disease studies are concentrated in New Haven, Brookfield, Farmington and Hartford. 5 of the 8 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who heart disease trials usually look for

Listings define the condition precisely: an ejection fraction range for heart failure, a heart attack or stent within a recent window, cholesterol still above target on a statin, or a lipoprotein(a) level above a threshold. They usually ask that your current heart medicines have been stable for a month or more. Common exclusions are a very recent procedure, advanced kidney disease and another illness that limits life expectancy. Ages generally run from 18 with no upper limit.

What taking part involves

Screening includes an ECG, blood work and often an echocardiogram. Outcomes trials are long but light: a pill or injection added to your treatment, visits every three to six months and phone check-ins between. Drug trials for heart failure run three to twelve months with monthly visits. Device trials involve a procedure and follow-up imaging. Your existing heart medicines continue throughout; study treatment and tests are free, and travel is usually reimbursed.

Questions worth asking the study team

Whether anything about your current treatment would change; how long the trial runs and how often you must come in; what is being measured and what you will be told about your own results; and whether your cardiologist will receive updates.

Showing 8 of 8 recruiting Heart Disease trials in Connecticut

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NA Hartford, Connecticut +4 sites NCT04124120
This trial is looking for women aged 18 and older who need heart surgery. Participants will help researchers compare two types of artery grafts used in heart operations to see which works better.
Recruiting
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
PHASE3 Phoenix, Arizona +4 sites NCT05918211
This trial is looking for adolescents aged 12 to under 19 who have had the Fontan procedure. Participants will take either udenafil or a placebo to help assess its safety and effectiveness.
Recruiting
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
NA New Haven, Connecticut +4 sites NCT07214376
This trial is looking for patients with heart failure and pulmonary hypertension. Participants will receive a specific treatment and be monitored for three years to evaluate safety and effectiveness.
Recruiting
Circulating Markers for Ischemic Heart Disease
N/A Farmington, Connecticut NCT00762333
This trial is looking for people aged 18 and older who have had a heart attack. Participants will have blood tests to check for certain proteins related to heart damage.
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
PHASE3 La Jolla, California +4 sites NCT06563895
This trial is looking for adults who carry a specific genetic variant that can lead to a heart condition but have not yet shown any symptoms. Participants will receive an experimental drug called acoramidis to see if it can prevent heart issues.
Recruiting
Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)
NA New Haven, Connecticut +2 sites NCT07449325
This trial is looking for adults with ongoing angina or similar symptoms caused by coronary microvascular dysfunction. Participants will receive a device designed to relieve their symptoms and will need to undergo several evaluations before being selected.
Recruiting
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
N/A Brookfield, Connecticut NCT05972070
This trial is looking for adults over 18 who have recently had heart surgery. Participants will take part in home-based cardiac rehabilitation with support from their therapists through telemedicine.
Recruiting
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions
PHASE4 New Haven, Connecticut +4 sites NCT05786417
This trial is looking for older adults with stable angina and multiple health conditions. Participants will take medication to evaluate its effectiveness and side effects.
Recruiting
See all 8 Heart Disease trials in Connecticut

Where the Heart Disease studies are in Connecticut

Research sites running the most studies
  • Yale School of Medicine, New Haven2 trials
  • Yale University, New Haven2 trials
  • Hartford Hospital, Hartford1 trial
  • ROMTech, Brookfield1 trial
  • University of Connecticut Health Center, Farmington1 trial
  • Yale University Hospital, New Haven1 trial
By city

Counts are recruiting studies listing at least one site in Connecticut, from ClinicalTrials.gov, refreshed every two days.

Heart Disease clinical trials in Connecticut: common questions

How many Heart Disease clinical trials are recruiting in Connecticut?
TrialFinder currently lists 8 recruiting Heart Disease clinical trials with study sites in Connecticut. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Heart Disease clinical trials located in Connecticut?
Study sites for the Heart Disease trials listed on this page include Hartford, New Haven, Farmington, Brookfield. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Heart Disease clinical trial in Connecticut?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Heart Disease trials in Connecticut also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Heart Disease clinical trial in Connecticut?
Each study sets its own criteria based on age, Heart Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I have to stop my heart medicines to join a trial?
Almost never. Heart disease trials add a study treatment to the medicines you already take, and your own cardiologist continues to manage them. A trial that requires a change says so in its listing.
What is a cardiovascular outcomes trial?
A large, multi-year study in which participants take a study medicine or placebo on top of standard care while the trial counts events such as heart attacks and hospital stays. Visits are infrequent, and the drug is provided free throughout.
Can I join a trial after a heart attack or stent?
Yes. Many trials enroll in the weeks after a heart attack or procedure, because that is when the next event is most likely. The window is stated in the listing, so ask soon after discharge.
Heart Disease Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Heart Disease Trials

Cardiovascular trials study statins, PCSK9 inhibitors, heart failure devices, cardiac rehabilitation protocols, and interventional procedures for coronary artery disease.

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