Heart Disease Trials / Trials in New York
37 Recruiting Trials

Clinical Trials
for Heart Disease in New York

37 clinical trials for Heart Disease are currently recruiting participants at study sites in New York. Study-related care is provided at no cost.

37
Recruiting trials
66
Study sites
14
Cities
13
Industry-sponsored
2
Phase 2
2
Phase 3

Heart Disease clinical trials in New York: what to expect

Heart disease trials cover heart failure, coronary artery disease, atrial fibrillation, high cholesterol and lipoprotein(a), and the devices and procedures used to treat them. The largest are outcomes trials: thousands of people take a study medicine or placebo on top of their usual treatment for several years while the trial counts heart attacks, strokes and hospital stays. Smaller studies test new heart failure drugs, cholesterol-lowering injections given a few times a year, cardiac rehabilitation programs and monitoring devices.

In New York, recruiting heart disease studies are concentrated in New York, The Bronx, Rochester and Brooklyn, with sites in 10 other cities. 13 of the 37 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who heart disease trials usually look for

Listings define the condition precisely: an ejection fraction range for heart failure, a heart attack or stent within a recent window, cholesterol still above target on a statin, or a lipoprotein(a) level above a threshold. They usually ask that your current heart medicines have been stable for a month or more. Common exclusions are a very recent procedure, advanced kidney disease and another illness that limits life expectancy. Ages generally run from 18 with no upper limit.

What taking part involves

Screening includes an ECG, blood work and often an echocardiogram. Outcomes trials are long but light: a pill or injection added to your treatment, visits every three to six months and phone check-ins between. Drug trials for heart failure run three to twelve months with monthly visits. Device trials involve a procedure and follow-up imaging. Your existing heart medicines continue throughout; study treatment and tests are free, and travel is usually reimbursed.

Questions worth asking the study team

Whether anything about your current treatment would change; how long the trial runs and how often you must come in; what is being measured and what you will be told about your own results; and whether your cardiologist will receive updates.

Showing 20 of 37 recruiting Heart Disease trials in New York

Use of GeriKit to Better Phenotype Older Adults With Ischemic Heart Disease
NA New York, New York NCT05788666
This trial is looking for older adults aged 75 and above who have recently been hospitalized for certain heart conditions. Participants will use the GeriKit app to help improve care and research for older patients.
Recruiting
BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease
NA Phoenix, Arizona +4 sites NCT07582848
This trial is looking for mothers and their infants who have been diagnosed with congenital heart disease. Participants will receive support to help increase direct breastfeeding.
Recruiting
Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)
NA Phoenix, Arizona +4 sites NCT07582861
This trial is looking for pregnant individuals or mothers of infants diagnosed with congenital heart disease (CHD). Participants will receive usual care plus a virtual psychological intervention to help manage their situation.
Recruiting
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
NA New York, New York +4 sites NCT03891160
This trial is looking for children with Congenital Heart Disease who are going to have a ventricular assist device (VAD) placed. Participants will help researchers understand if using a 3D model of their heart can improve surgery outcomes.
Recruiting
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
N/A New York, New York +4 sites NCT06932081
This trial is looking for adults with congenital heart defects who have started treatment with SGLT2 inhibitors. Participation involves allowing researchers to collect data on how these drugs affect heart health and safety.
Recruiting
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NA Los Angeles, California +4 sites NCT04124120
This trial is looking for women aged 18 and older who need heart surgery. Participants will help researchers compare two types of artery grafts used in heart operations to see which works better.
Recruiting
Abbott Structural Heart Device Registry
N/A Los Angeles, California +4 sites NCT06590467
This trial is looking for patients who need or have had heart device implants. Participants will help gather information about the safety and performance of specific heart devices used in hospitals.
Recruiting
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
PHASE3 Phoenix, Arizona +4 sites NCT05918211
This trial is looking for adolescents aged 12 to under 19 who have had the Fontan procedure. Participants will take either udenafil or a placebo to help assess its safety and effectiveness.
Recruiting
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study
NA Roslyn, New York +4 sites NCT06854458
This trial is looking for people who experience chest pain or shortness of breath to find out if these symptoms are due to a heart issue. Participants will undergo a special heart imaging test during exercise-like conditions to measure blood flow to the heart.
Recruiting
Autus Valve Continued Access Study (CAS)
NA Los Angeles, California +4 sites NCT07466745
This trial is looking for children aged 18 months to 16 years who need surgery to replace their pulmonary valve. Participants will have regular check-ups over 10 years to see how well the Autus Valve works as they grow.
Recruiting
Dynamic Critical Congenital Heart Screening With Addition of Perfusion Measurements
NA Queens, New York +2 sites NCT05637814
This trial is looking for newborns under 22 days old who might have heart issues. Participants will undergo a special screening test to check for critical congenital heart disease.
Recruiting
Physical Activity and Cognitive Development in Children
N/A New York, New York NCT02542683
This trial is looking for children with congenital heart diseases who are scheduled for cardiac surgery. Participants will compare their physical activity and thinking skills before and after surgery and may join a physical activity program for up to 12 months.
Recruiting
Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease
NA New York, New York NCT07843004
This trial is looking for people aged 40 and over who have had an ECG in the Emergency Department. If you join, doctors will use a new tool called EchoNext to check for hidden heart issues and may suggest further tests if they find something unusual.
Recruiting
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study
NA Stanford, California +4 sites NCT07525843
This trial is looking for teens aged 12-17 with congenital heart disease. Participants will take part in a 5-week online program that aims to help them improve their ability to handle stress and live better lives.
Recruiting
Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)
N/A New York, New York NCT06575270
Recruiting
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
NA Tucson, Arizona +4 sites NCT07214376
This trial is looking for patients with heart failure and pulmonary hypertension. Participants will receive a specific treatment and be monitored for three years to evaluate safety and effectiveness.
Recruiting
Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia
N/A Valhalla, New York NCT07814079
This trial is looking for patients with heart disease who experience episodes of rapid heartbeats called ventricular tachycardia. Participants will have special mapping done to find and block specific channels in the heart that cause these episodes.
Recruiting
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
N/A Birmingham, Alabama +4 sites NCT02852031
This trial is looking for newborns diagnosed with Hypoplastic Left Heart Syndrome (HLHS) who are meant to have a specific heart surgery called the Norwood procedure. The goal is to gather information to help improve care for these infants.
Recruiting
Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)
NA New York, New York +4 sites NCT07130994
This trial is looking for patients with significant mitral regurgitation who are experiencing symptoms. Participating involves receiving a treatment using the SATURN TMVR System and undergoing various assessments throughout the study.
Recruiting
The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery
NA New York, New York NCT07485738
This trial is looking for patients who are having their first heart bypass surgery. Participants will help researchers learn about a new tool that checks blood flow during the surgery.
Recruiting
See all 37 Heart Disease trials in New York

Where the Heart Disease studies are in New York

Research sites running the most studies
  • Mount Sinai Hospital, New York4 trials
  • Weill Cornell Medicine, New York4 trials
  • Columbia University Medical Center, New York3 trials
  • Icahn School of Medicine at Mount Sinai, New York3 trials
  • Children's Hospital of New York, New York2 trials
  • Columbia University Irving Medical Center, New York2 trials
By city

Counts are recruiting studies listing at least one site in New York, from ClinicalTrials.gov, refreshed every two days.

Heart Disease clinical trials in New York: common questions

How many Heart Disease clinical trials are recruiting in New York?
TrialFinder currently lists 37 recruiting Heart Disease clinical trials with study sites in New York. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Heart Disease clinical trials located in New York?
Study sites for the Heart Disease trials listed on this page include New York, Roslyn, Queens, Valhalla. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Heart Disease clinical trial in New York?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Heart Disease trials in New York also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Heart Disease clinical trial in New York?
Each study sets its own criteria based on age, Heart Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I have to stop my heart medicines to join a trial?
Almost never. Heart disease trials add a study treatment to the medicines you already take, and your own cardiologist continues to manage them. A trial that requires a change says so in its listing.
What is a cardiovascular outcomes trial?
A large, multi-year study in which participants take a study medicine or placebo on top of standard care while the trial counts events such as heart attacks and hospital stays. Visits are infrequent, and the drug is provided free throughout.
Can I join a trial after a heart attack or stent?
Yes. Many trials enroll in the weeks after a heart attack or procedure, because that is when the next event is most likely. The window is stated in the listing, so ask soon after discharge.
Heart Disease Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Heart Disease Trials

Cardiovascular trials study statins, PCSK9 inhibitors, heart failure devices, cardiac rehabilitation protocols, and interventional procedures for coronary artery disease.

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