61 Recruiting Trials

Clinical Trials
for Arthritis in New York

61 clinical trials for Arthritis are currently recruiting participants at study sites in New York. Study-related care is provided at no cost.

61
Recruiting trials
64
Study sites
22
Cities
33
Industry-sponsored
13
Phase 2
14
Phase 3

Arthritis clinical trials in New York: what to expect

Arthritis trials are split by type. Rheumatoid arthritis studies test biologics, targeted pills and, more recently, cell therapies in people whose joints stay inflamed despite methotrexate or a biologic. Knee osteoarthritis studies test injections meant to slow cartilage loss, new pain medicines, devices and exercise and weight programs. Psoriatic arthritis, ankylosing spondylitis and gout each have their own trials, and a listing will always say which type it enrolls.

In New York, recruiting arthritis studies are concentrated in New York, Rochester, Brooklyn and Buffalo, with sites in 18 other cities. 33 of the 61 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who arthritis trials usually look for

Rheumatoid arthritis trials count swollen and tender joints and measure inflammation in the blood at screening, and ask that a standard medicine has not worked well enough; methotrexate usually continues, while a current biologic is stopped after a washout. Knee osteoarthritis trials need an X-ray showing moderate damage, a pain score above a threshold, and no steroid or hyaluronic acid injection in the past few months; many set a weight limit. Ages are usually 18 to 80, and most trials exclude pregnancy and a recent serious infection.

What taking part involves

Screening includes a joint exam, blood work and X-rays or an MRI. Rheumatoid arthritis trials run six to twelve months with visits every four weeks for an injection or infusion and labs; placebo arms are common, with rescue rules so no one stays on an ineffective treatment for long. Osteoarthritis injection trials give one or a few injections at the site and follow you for six to twenty-four months with pain diaries and imaging. Exercise trials involve supervised sessions for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Which of your medicines continue; how long any washout is; the chance of placebo and the rescue rules; how imaging is scheduled; and whether an extension lets everyone receive the active treatment.

Showing 20 of 61 recruiting Arthritis trials in New York

Osteochondral Allograft in the Surgical Treatment of Basal Joint Arthritis
NA New York, New York NCT03722537
This trial is looking for adults with basal joint arthritis who need surgery. Participants will receive a new type of surgery and will have follow-up visits for a year after the procedure.
Recruiting
Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis
PHASE2 New York, New York NCT05020028
This trial is looking for people with knee osteoarthritis who have been experiencing pain for at least three months. Participants will take cannabidiol tablets to see if it helps reduce their pain and improve their daily function.
Recruiting
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
PHASE3 Chandler, Arizona +4 sites NCT06671483
This trial is looking for adults with psoriatic arthritis who have not taken biologic medicines. Participants will receive either the study drug, a comparator, or a placebo over a period of up to 60 weeks.
Recruiting
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
PHASE3 Mobile, Alabama +4 sites NCT07353931
This trial is looking for adults who are at least 50 years old and have knee pain from osteoarthritis, as well as being overweight or obese. It’s important that they haven't had a recent heart issue or surgery for weight loss, and they shouldn’t have diabetes. Participants also need to have tried losing weight through diet without success.
Recruiting
A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis
PHASE3 North New Hyde Park, New York +4 sites NCT06869551
This trial is looking for children with juvenile psoriatic arthritis who have not had success with previous treatments. Participants will take part in evaluations to help understand the safety and effectiveness of the drug Deucravacitinib.
Recruiting
RA-PRO PRAGMATIC TRIAL
PHASE3 Auburn, Alabama +4 sites NCT04692493
This trial is looking for people with active rheumatoid arthritis who have not improved with their current treatment. Participants will have the chance to switch to a different type of medication to see if it helps their condition.
Recruiting
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
PHASE3 Valhalla, New York +4 sites NCT05609630
This trial is looking for children and teens aged 1 to less than 18 with systemic juvenile idiopathic arthritis (sJIA). Participants will take either a new oral medicine called upadacitinib or a reference treatment called tocilizumab for about a year and will be monitored for their health and side effects.
Recruiting
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
PHASE3 Avondale, Arizona +4 sites NCT06641089
This trial is looking for adults with active psoriatic arthritis who did not respond well to past treatments. Participants will take sonelokimab or a placebo to see how well it works and if it is safe.
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
PHASE3 Little Rock, Arkansas +4 sites NCT06100744
This trial is looking for children with juvenile psoriatic arthritis (jPsA). Participants will receive either risankizumab or adalimumab as injections and be monitored for their symptoms and safety over time.
Recruiting
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
PHASE2 Avondale, Arizona +4 sites NCT07137598
This trial is looking for people with moderate to severe rheumatoid arthritis who haven't had good results with previous treatments or can't tolerate them. Participants will receive either the study drug or a placebo to see how it helps with their condition.
Recruiting
Preventing Injured Knees From osteoArthritis: Severity Outcomes
PHASE2 Atlanta, Georgia +4 sites NCT06096259
This trial is looking for people aged 18-45 who have had an ACL injury and are planning to have surgery. Participants will take either metformin or a placebo that looks like metformin to see if it helps reduce pain related to post-traumatic osteoarthritis.
Recruiting
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
PHASE2 Peoria, Arizona +4 sites NCT06972446
This trial is looking for patients with rheumatoid arthritis who have not responded to certain treatments. Participants will try new medications and attend regular check-ups to monitor their health.
Recruiting
A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis
PHASE1 La Jolla, California +4 sites NCT07412704
This trial is looking for adults with rheumatoid arthritis that is hard to treat. Participants will take a medication called BMS-986528 and help researchers understand its effects.
Recruiting
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
PHASE2 Sun City, Arizona +4 sites NCT07486960
This trial is looking for adults with Psoriatic Arthritis who are experiencing active symptoms. Participants will take a study medicine called tulisokibart or a placebo to see if it helps reduce their symptoms better than the placebo.
Recruiting
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
PHASE2 Birmingham, Alabama +4 sites NCT07641517
This trial is looking for people with knee pain from osteoarthritis to test a new treatment. Participants will need to meet specific health criteria to join the study.
Recruiting
A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee
PHASE2 Birmingham, Alabama +4 sites NCT06884865
This trial is looking for people aged 45 to 80 who have been dealing with knee pain from osteoarthritis for at least a year and have tried other treatments that didn’t work. They’re also looking for individuals who don’t have certain autoimmune diseases or infections and haven't had specific knee treatments in the last six months.
Recruiting
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
PHASE2 Stony Brook, New York NCT06237153
This trial is looking for adults with thumb joint pain from arthritis to see if a special steroid injection can help reduce pain and improve thumb function. Participants will receive an injection and return for follow-up visits to check on their progress.
Recruiting
PRP for Glenohumeral Osteoarthritis
PHASE4 New York, New York NCT05675527
This trial is looking for adults aged 18 to 100 who have shoulder pain from osteoarthritis. Participants will receive one injection of either low-dose PRP, high-dose PRP, or saline to see which is more effective.
Recruiting
A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
PHASE4 Avondale, Arizona +4 sites NCT06864026
This trial is looking for people with active psoriatic arthritis who are overweight or obese. Participants will add a medication called tirzepatide to their current treatment with ixekizumab for up to 12 months.
Recruiting
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
PHASE1 New York, New York +4 sites NCT06751238
This trial is looking for children aged 2 to 17 with juvenile psoriatic arthritis (JPsA) who are having trouble with current treatments. Participants will receive multiple doses of a medication called secukinumab to see how well it works and if it is safe.
Recruiting

Where the Arthritis studies are in New York

  • Hospital for Special Surgery, New York12 trials
  • NYU Langone Health, New York6 trials
  • Rochester Clinical Research, LLC, Rochester3 trials
  • University of Rochester, Rochester3 trials
  • Columbia University Irving Medical Center, New York2 trials
  • Columbia University Medical Center, New York2 trials

Counts are recruiting studies listing at least one site in New York, from ClinicalTrials.gov, refreshed every two days.

Arthritis clinical trials in New York: common questions

How many Arthritis clinical trials are recruiting in New York?
TrialFinder currently lists 61 recruiting Arthritis clinical trials with study sites in New York. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Arthritis clinical trials located in New York?
Study sites for the Arthritis trials listed on this page include New York, North New Hyde Park, Valhalla, Stony Brook. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Arthritis clinical trial in New York?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Arthritis trials in New York also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Arthritis clinical trial in New York?
Each study sets its own criteria based on age, Arthritis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Which type of arthritis do trials enroll?
Each listing names one: rheumatoid, osteoarthritis (most often knee), psoriatic, ankylosing spondylitis or gout. Rheumatoid and knee osteoarthritis have the most recruiting trials.
Do I need to stop my arthritis medicine to join a trial?
For rheumatoid arthritis, methotrexate usually continues and a biologic is stopped after a supervised washout. Osteoarthritis trials ask that you have had no joint injection for a few months and may limit daily pain medicine.
Are there arthritis trials that do not involve medicine?
Yes. Exercise, physical therapy, weight management, braces and devices, and diet studies all recruit, mostly for knee and hip osteoarthritis.
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Arthritis trials test biologics, JAK inhibitors, stem-cell therapies, and pain-management protocols for rheumatoid arthritis, osteoarthritis, and psoriatic arthritis.

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