21 Recruiting Trials

Clinical Trials
for Arthritis in Oregon

21 clinical trials for Arthritis are currently recruiting participants at study sites in Oregon. Study-related care is provided at no cost.

21
Recruiting trials
18
Study sites
4
Cities
17
Industry-sponsored
2
Phase 2
6
Phase 3

Arthritis clinical trials in Oregon: what to expect

Arthritis trials are split by type. Rheumatoid arthritis studies test biologics, targeted pills and, more recently, cell therapies in people whose joints stay inflamed despite methotrexate or a biologic. Knee osteoarthritis studies test injections meant to slow cartilage loss, new pain medicines, devices and exercise and weight programs. Psoriatic arthritis, ankylosing spondylitis and gout each have their own trials, and a listing will always say which type it enrolls.

In Oregon, recruiting arthritis studies are concentrated in Portland, Eugene, Bend and Oregon City. 17 of the 21 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who arthritis trials usually look for

Rheumatoid arthritis trials count swollen and tender joints and measure inflammation in the blood at screening, and ask that a standard medicine has not worked well enough; methotrexate usually continues, while a current biologic is stopped after a washout. Knee osteoarthritis trials need an X-ray showing moderate damage, a pain score above a threshold, and no steroid or hyaluronic acid injection in the past few months; many set a weight limit. Ages are usually 18 to 80, and most trials exclude pregnancy and a recent serious infection.

What taking part involves

Screening includes a joint exam, blood work and X-rays or an MRI. Rheumatoid arthritis trials run six to twelve months with visits every four weeks for an injection or infusion and labs; placebo arms are common, with rescue rules so no one stays on an ineffective treatment for long. Osteoarthritis injection trials give one or a few injections at the site and follow you for six to twenty-four months with pain diaries and imaging. Exercise trials involve supervised sessions for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Which of your medicines continue; how long any washout is; the chance of placebo and the rescue rules; how imaging is scheduled; and whether an extension lets everyone receive the active treatment.

Showing 20 of 21 recruiting Arthritis trials in Oregon

RA-PRO PRAGMATIC TRIAL
PHASE3 Auburn, Alabama +4 sites NCT04692493
This trial is looking for people with active rheumatoid arthritis who have not improved with their current treatment. Participants will have the chance to switch to a different type of medication to see if it helps their condition.
Recruiting
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
PHASE3 Phoenix, Arizona +4 sites NCT05609630
This trial is looking for children and teens aged 1 to less than 18 with systemic juvenile idiopathic arthritis (sJIA). Participants will take either a new oral medicine called upadacitinib or a reference treatment called tocilizumab for about a year and will be monitored for their health and side effects.
Recruiting
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
PHASE3 Avondale, Arizona +4 sites NCT06641089
This trial is looking for adults with active psoriatic arthritis who did not respond well to past treatments. Participants will take sonelokimab or a placebo to see how well it works and if it is safe.
Recruiting
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
PHASE3 Roseville, California +4 sites NCT07226258
This trial is looking for adults with chronic knee pain due to osteoarthritis. Participants will receive a single dose of SL1002 to evaluate its effects.
Recruiting
Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans
PHASE3 Portland, Oregon +4 sites NCT06488144
This trial is looking for veterans with knee osteoarthritis who are starting physical therapy. Participants will receive support and encouragement to maintain their exercise routine over two years with follow-up visits.
Recruiting
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
PHASE2 Chandler, Arizona +4 sites NCT07133633
This trial is looking for people with a type of arthritis called radiographic axial spondyloarthritis. Participants will take a medication called tulisokibart to see if it helps improve their symptoms compared to a placebo, which looks like the medication but doesn’t contain any active ingredients.
Recruiting
A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis
PHASE1 La Jolla, California +4 sites NCT07412704
This trial is looking for adults with rheumatoid arthritis that is hard to treat. Participants will take a medication called BMS-986528 and help researchers understand its effects.
Recruiting
A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis
PHASE4 Portland, Oregon +4 sites NCT06454188
This trial is looking for adults with active psoriatic arthritis and evidence of spondyloarthritis. Participants will receive treatment with upadacitinib and undergo various assessments throughout the study.
Recruiting
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
PHASE1 Loma Linda, California +4 sites NCT06751238
This trial is looking for children aged 2 to 17 with juvenile psoriatic arthritis (JPsA) who are having trouble with current treatments. Participants will receive multiple doses of a medication called secukinumab to see how well it works and if it is safe.
Recruiting
Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis
PHASE1 Scottsdale, Arizona +4 sites NCT06201416
This trial is looking for adults with moderate to severe rheumatoid arthritis who have not responded well to other treatments. Participants will receive a single dose of SBT777101 and will be monitored for safety and effects.
Recruiting
MISHA Post-Market Clinical Study
NA Portland, Oregon +3 sites NCT06118892
This trial is looking for adults with knee osteoarthritis who are experiencing pain and have not found relief from other treatments. Participants will be monitored for up to five years after receiving the MISHA Knee System.
Recruiting
ConsideRAte Study - Splenic Stimulation for RA
NA Anniston, Alabama +4 sites NCT05003310
This trial is looking for people with rheumatoid arthritis that hasn’t improved with other treatments. Participants will receive stimulation therapy using a special device to see if it helps their condition.
Recruiting
Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration
NA Portland, Oregon +4 sites NCT06423300
This trial is looking for people between the ages of 22 and 65 who have significant knee pain caused by cartilage damage. They're specifically looking for individuals who haven't found relief from other treatments for at least six months. However, people with certain knee problems or past surgeries may not qualify for the study.
Recruiting
Z1 Hip System: Post-Market Clinical Follow Up Study
N/A Portland, Oregon +4 sites NCT07104279
Recruiting
A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
N/A Eugene, Oregon +4 sites NCT07118501
This trial is looking for adults who are having ankle replacement surgery. Participants will share their experience with pain and quality of life after the surgery.
Recruiting
AETOS Shoulder System
N/A Bend, Oregon +4 sites NCT06319911
This trial is looking for adults needing shoulder replacement surgery due to arthritis. Participants will receive the AETOS Shoulder System and will attend follow-up visits to monitor their recovery.
Recruiting
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
PHASE3 Escondido, California +4 sites NCT07509307
This trial is looking for people with excess weight and knee osteoarthritis. Participants will receive an injection either of the study medicine or a placebo once a week for a set period of time.
Recruiting
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
N/A Birmingham, Alabama +4 sites NCT02418442
This trial is looking for children and teenagers with rheumatic joint diseases. If you join, you will help researchers gather important information about treatments used for these conditions.
Recruiting
MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
NA La Mesa, California +4 sites NCT07332182
This trial is looking for patients aged 18 to 60 with specific knee issues. Participants will compare a new treatment called MaioRegen Prime with a common surgery to see which works better.
Recruiting
Persona Revision Knee System Outcomes
N/A Fayetteville, Arkansas +4 sites NCT04821154
This trial is looking for patients who have had knee surgery and need additional treatment. Participants will be evaluated for the safety and effectiveness of the Persona Revision Knee System.
Recruiting

Where the Arthritis studies are in Oregon

  • Oregon Health and Science University, Portland4 trials
  • Casey Eye Institute - Oregon Health & Science University, Portland1 trial
  • Center for Orthopedics and Neurosurgical Care, Bend1 trial
  • Clinical Site, Portland1 trial
  • Legacy Emanuel Research Hosp Portland, Portland1 trial
  • Local Institution - 0066, Portland1 trial

Counts are recruiting studies listing at least one site in Oregon, from ClinicalTrials.gov, refreshed every two days.

Arthritis clinical trials in Oregon: common questions

How many Arthritis clinical trials are recruiting in Oregon?
TrialFinder currently lists 21 recruiting Arthritis clinical trials with study sites in Oregon. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Arthritis clinical trials located in Oregon?
Study sites for the Arthritis trials listed on this page include Portland, Eugene, Bend. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Arthritis clinical trial in Oregon?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Arthritis trials in Oregon also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Arthritis clinical trial in Oregon?
Each study sets its own criteria based on age, Arthritis diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Which type of arthritis do trials enroll?
Each listing names one: rheumatoid, osteoarthritis (most often knee), psoriatic, ankylosing spondylitis or gout. Rheumatoid and knee osteoarthritis have the most recruiting trials.
Do I need to stop my arthritis medicine to join a trial?
For rheumatoid arthritis, methotrexate usually continues and a biologic is stopped after a supervised washout. Osteoarthritis trials ask that you have had no joint injection for a few months and may limit daily pain medicine.
Are there arthritis trials that do not involve medicine?
Yes. Exercise, physical therapy, weight management, braces and devices, and diet studies all recruit, mostly for knee and hip osteoarthritis.
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Arthritis trials test biologics, JAK inhibitors, stem-cell therapies, and pain-management protocols for rheumatoid arthritis, osteoarthritis, and psoriatic arthritis.

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