11 Recruiting Trials

Clinical Trials
for Alzheimer's in Oregon

11 clinical trials for Alzheimer's are currently recruiting participants at study sites in Oregon. Study-related care is provided at no cost.

11
Recruiting trials
7
Study sites
2
Cities
8
Industry-sponsored
5
Phase 2
4
Phase 3

Alzheimer's clinical trials in Oregon: what to expect

Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.

In Oregon, recruiting alzheimer's studies are concentrated in Portland and Tigard. 8 of the 11 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Alzheimer's trials usually look for

Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.

What taking part involves

Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.

Questions worth asking the study team

Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.

Showing 11 of 11 recruiting Alzheimer's trials in Oregon

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
PHASE3 Long Beach, California +4 sites NCT06976216
This trial is looking for people with mild to moderate Alzheimer's disease who want to help test a new treatment. Participants will need a caregiver to support them and attend study visits.
Recruiting
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
PHASE2 Oakland, California +4 sites NCT07688213
This trial is looking for people aged 55 to 85 with mild Alzheimer's disease or mild cognitive impairment. Participants will take a daily pill and might continue in the study for up to 111 weeks.
Recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
PHASE2 Phoenix, Arizona +4 sites NCT07094516
This trial is looking for people aged 50 to 85 with early Alzheimer's disease. Participants will take VHB937 for up to 72 weeks and will have regular visits with a study partner.
Recruiting
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
PHASE3 Birmingham, Alabama +4 sites NCT07177352
This trial is looking for individuals who may qualify for Alzheimer's disease research studies. Participants will be assessed to see if they can join related interventional studies.
Recruiting
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
PHASE2 Murrieta, California +4 sites NCT07284472
This trial is looking for adults aged 55 to 90 with Alzheimer's disease dementia who experience significant agitation. Participants will be evaluated to see how safe and effective the treatments EXV-802 and EXV-801 are for reducing their agitation.
Recruiting
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
PHASE3 Phoenix, Arizona +4 sites NCT07170150
This trial is looking for people with early symptoms of Alzheimer's disease. Participants will take a medication called trontinemab and go through tests like imaging and assessments to see how well the treatment works and if it is safe.
Recruiting
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
PHASE2 Phoenix, Arizona +4 sites NCT06887192
This trial is looking for men and women aged 55 to 90 who have Alzheimer's disease and are experiencing symptoms like hallucinations or delusions. They need to have been living in the same place for at least six weeks and have a support person who can help track their health. However, it’s important to note that people who are seriously ill, have other major medical issues, or have substance abuse problems can't participate.
Recruiting
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
PHASE2 Phoenix, Arizona +4 sites NCT06847321
This trial is looking for people with mild to moderate Alzheimer's who also have a specific infection. Participants will take a daily capsule and attend study visits over 64 weeks.
Recruiting
Trial-Ready Cohort-Down Syndrome (TRC-DS)
N/A Phoenix, Arizona +4 sites NCT04165109
This trial is looking for healthy adults with Down syndrome aged 25-55. Participants will be assessed over time through tests and evaluations to help understand Alzheimer's disease in people with Down syndrome.
Recruiting
Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
PHASE1 Portland, Oregon NCT05591027
This trial is looking for older adults with mild cognitive impairment or Alzheimer's disease. Participants will take a Centella asiatica water extract for 6 weeks and undergo tests to see how well it works and evaluate its safety.
Recruiting
OCT Angiography and NRAI in Dementia
N/A Portland, Oregon NCT03761381
This trial is looking for people aged over 55 with mild dementia or Alzheimer's disease. Participants will have tests to check their eye health and blood flow in the retina.
Recruiting

Where the Alzheimer's studies are in Oregon

  • Oregon Health & Science University, Portland4 trials
  • Summit Research Network Inc., Portland2 trials
  • Clinical Site, Tigard1 trial
  • Neural Net Research, Portland1 trial
  • Summit Headlands, Portland1 trial
  • Summit Research Network - Portland - Northwest Vaughn Street- Site Number : 8400002, Portland1 trial

Counts are recruiting studies listing at least one site in Oregon, from ClinicalTrials.gov, refreshed every two days.

Alzheimer's clinical trials in Oregon: common questions

How many Alzheimer's clinical trials are recruiting in Oregon?
TrialFinder currently lists 11 recruiting Alzheimer's clinical trials with study sites in Oregon. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in Oregon?
Study sites for the Alzheimer's trials listed on this page include Portland. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in Oregon?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in Oregon also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in Oregon?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.

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