Alzheimer's Trials / Trials in Wisconsin
8 Recruiting Trials

Clinical Trials
for Alzheimer's in Wisconsin

8 clinical trials for Alzheimer's are currently recruiting participants at study sites in Wisconsin. Study-related care is provided at no cost.

8
Recruiting trials
6
Study sites
2
Cities
2
Industry-sponsored
2
Phase 3

Alzheimer's clinical trials in Wisconsin: what to expect

Alzheimer's trials now span the whole course of the disease. Prevention studies enroll people with normal memory who have early signs of amyloid in the brain; treatment studies enroll people with mild cognitive impairment or early Alzheimer's and test the next generation of antibodies, tau-targeting drugs and combinations; and symptom studies address agitation, sleep and depression in later stages. Alongside drugs there are trials of exercise, cognitive training, blood tests for diagnosis and support programs for care partners.

In Wisconsin, recruiting alzheimer's studies are concentrated in Madison and Milwaukee. 2 of the 8 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who Alzheimer's trials usually look for

Most drug trials enroll ages 50 to 85 and define a stage with a memory test score range, then confirm Alzheimer's with an amyloid PET scan, a spinal fluid test or, increasingly, a blood test, all done by the study. Nearly every trial requires a study partner: someone who knows you well, attends visits and answers questions about daily life. Common exclusions are another cause of memory loss, a recent stroke and, for antibody trials, some blood thinners or MRI findings. Prevention trials enroll people with no symptoms at all.

What taking part involves

Screening is longer than for most conditions, often several visits over a few weeks with memory testing, an MRI and an amyloid test. Antibody trials then involve an infusion or injection every two to four weeks, regular safety MRIs and visits for eighteen months to four years, with an extension in which everyone receives the drug. Lifestyle trials involve classes or coaching for six to twenty-four months. All study care is free and travel is usually reimbursed for you and your partner.

Questions worth asking the study team

Whether you will be told your amyloid or genetic results; what the MRI safety monitoring involves; how much time the study partner must give; whether there is an extension after the placebo period; and what happens if memory worsens during the study.

Showing 8 of 8 recruiting Alzheimer's trials in Wisconsin

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
PHASE3 Chandler, Arizona +4 sites NCT07011745
This trial is looking for adults with agitation related to Alzheimer's Disease. Participants will receive a treatment and will be asked to have their caregiver attend visits and help with the study.
Recruiting
Speech Pattern Evaluation and Analysis for Knowledge of AD
N/A Madison, Wisconsin NCT06230783
This trial is looking for adults aged 40-80 who are either healthy or have mild cognitive issues. Participants will do speech exercises and surveys using an iPad and will be in the study for about 3 years.
Recruiting
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
PHASE3 Chandler, Arizona +4 sites NCT06937229
This trial is looking for people with agitation related to Alzheimer's Disease who have completed earlier studies. Participants will take a combination of two specific medications to see how well they work over time and if they are safe.
Recruiting
The Gut - PRO Study
PHASE1 Madison, Wisconsin NCT07413744
This trial is looking for older adults with mild cognitive impairment or Alzheimer's disease. Participants will take an oral probiotic supplement and be involved in the study for up to one year.
Recruiting
Trial-Ready Cohort-Down Syndrome (TRC-DS)
N/A Phoenix, Arizona +4 sites NCT04165109
This trial is looking for healthy adults with Down syndrome aged 25-55. Participants will be assessed over time through tests and evaluations to help understand Alzheimer's disease in people with Down syndrome.
Recruiting
Evaluation of a Decision-Support Tool for Blood Biomarker Testing for Alzheimer's Disease in Primary Care
NA Madison, Wisconsin NCT07812337
This trial is looking for primary care providers and older adults aged 50 or older. Participants will help evaluate a tool that aids doctors in discussing blood tests for Alzheimer’s disease.
Recruiting
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
NA Orange, California +4 sites NCT05929703
This trial is looking for older adults who are at least 70 years old and are expected to be in the hospital for at least three days. They should have some risks for confusion, like trouble thinking or seeing, and need to have a family member or caregiver who can be with them in the hospital. However, it won’t include anyone who is already confused when they arrive or can't communicate clearly.
Recruiting
Dementia Care Partner Hospital Assessment Tool
NA Madison, Wisconsin NCT05592366
This trial is looking for people who care for adults with dementia and who have been hospitalized. By participating, you will help test a tool that aims to improve care for these patients after they leave the hospital. The study lasts for 14 days.
Recruiting
See all 8 Alzheimer's trials in Wisconsin

Where the Alzheimer's studies are in Wisconsin

Research sites running the most studies
  • Local Institution - 2610, Milwaukee2 trials
  • University of Wisconsin, Madison2 trials
  • Meriter Hospital, Madison1 trial
  • School of Medicine and Public Health, University of Wisconsin, Madison1 trial
  • University of Wisconsin - Madison, Waisman Center, Co-Enrolling through ABC-DS Only, Madison1 trial
  • University of Wisconsin Hospitals and Clinics, Madison1 trial
By city

Counts are recruiting studies listing at least one site in Wisconsin, from ClinicalTrials.gov, refreshed every two days.

Alzheimer's clinical trials in Wisconsin: common questions

How many Alzheimer's clinical trials are recruiting in Wisconsin?
TrialFinder currently lists 8 recruiting Alzheimer's clinical trials with study sites in Wisconsin. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Alzheimer's clinical trials located in Wisconsin?
Study sites for the Alzheimer's trials listed on this page include Madison. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Alzheimer's clinical trial in Wisconsin?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Alzheimer's trials in Wisconsin also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Alzheimer's clinical trial in Wisconsin?
Each study sets its own criteria based on age, Alzheimer's diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need an Alzheimer's diagnosis to join a trial?
No. Prevention trials enroll people with normal memory and test them for early amyloid, and many treatment trials accept people with memory concerns who have not been formally diagnosed, then confirm the diagnosis as part of screening.
What is a study partner?
A family member or close friend who attends visits with you and answers questions about memory and daily activities. Nearly every Alzheimer's trial requires one, and their time is usually reimbursed too.
Will I learn my amyloid or APOE results?
Many trials now disclose amyloid status, since it decides eligibility, and explain what it means. Genetic results are disclosed in some trials and not others; ask before you consent.
Alzheimer's Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Alzheimer's Trials

Alzheimer's disease trials test amyloid-clearing antibodies, tau inhibitors, lifestyle interventions, and early-detection biomarkers for dementia prevention and treatment.

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