18 Recruiting Trials

Clinical Trials
for Hypertension in Wisconsin

18 clinical trials for Hypertension are currently recruiting participants at study sites in Wisconsin. Study-related care is provided at no cost.

18
Recruiting trials
22
Study sites
6
Cities
11
Industry-sponsored
1
Phase 2
5
Phase 3

Hypertension clinical trials in Wisconsin: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In Wisconsin, recruiting hypertension studies are concentrated in Milwaukee, Madison, Kenosha and Marshfield, with sites in 2 other cities. 11 of the 18 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 18 of 18 recruiting Hypertension trials in Wisconsin

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
PHASE3 Phoenix, Arizona +4 sites NCT07218029
This trial is looking for people who have completed a previous study with sotatercept for pulmonary arterial hypertension (PAH). Participants will be monitored for the long-term safety and tolerance of sotatercept along with their usual PAH treatments.
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
PHASE3 Alexander City, Alabama +4 sites NCT07288398
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
Recruiting
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
PHASE2 Los Angeles, California +4 sites NCT05587712
This trial is looking for children aged 1 to under 18 with pulmonary arterial hypertension (PAH). Participants will receive treatment with sotatercept over 24 weeks to evaluate safety and how the body processes the drug.
Recruiting
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
NA La Jolla, California +4 sites NCT04555161
This trial is looking for adults with pulmonary hypertension and issues with heart function. Participants will be assessed for safety and effectiveness of a specific treatment device.
Recruiting
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
N/A Birmingham, Alabama +4 sites NCT06388421
This trial is looking for adults with pulmonary hypertension related to interstitial lung disease. Participants will share information about their health and treatments to help improve understanding of these conditions.
Recruiting
Pulmonary Hypertension Association Registry
N/A Phoenix, Arizona +4 sites NCT04071327
This trial is looking for people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). Participants will provide information about their health and treatment to help improve care for these conditions.
Recruiting
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NA Scottsdale, Arizona +4 sites NCT06059638
This trial is looking for people with high blood pressure who need a pacemaker. Participants will try a new treatment that adjusts heart rhythms to help lower blood pressure.
Recruiting
Arterial Stiffness and Blood Pressure
NA Madison, Wisconsin +2 sites NCT06495710
This trial is looking for older veterans who have high blood pressure. Participants will be randomly assigned to different blood pressure treatment methods and will undergo tests to measure their blood vessel stiffness.
Recruiting
Clarifying the Optimal Application of SLT Therapy Trial
PHASE3 Laguna Hills, California +4 sites NCT04967989
This trial is looking for people with glaucoma or high eye pressure. Participants will receive a special eye treatment to see how effective it is at different energy levels.
Recruiting
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
PHASE3 Birmingham, Alabama +4 sites NCT07181109
This trial is looking for adults with high blood pressure that is not well controlled and have either a history of heart disease or are at high risk for heart disease. Participants will receive either the study drug, zilebesiran, or a placebo to see if it lowers the risk of serious heart-related events.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
N/A Phoenix, Arizona +4 sites NCT04278404
This trial is looking for children and young adults who are 21 years old or younger and are currently taking certain medications, or who have had a recent COVID-19 infection. They cannot be pregnant or have had certain recent medical procedures like dialysis, organ transplants, or other serious treatments. If you think your child might fit this description, it could be worth considering.
Recruiting
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
PHASE4 Birmingham, Alabama +4 sites NCT06468202
This trial is looking for pregnant individuals at risk of high blood pressure issues. Participants will take either a low or high dose of aspirin to see which is more effective in preventing these conditions.
Recruiting
Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
PHASE4 Kenosha, Wisconsin NCT06848946
This trial is looking for people with cataracts who also have glaucoma or high eye pressure. Participants will receive an iDose TR implant during cataract surgery to see if it helps lower eye pressure more than surgery alone.
Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NA Phoenix, Arizona +4 sites NCT06526195
This trial is looking for patients with advanced heart failure who are not dependent on intravenous medications. Participants will be evaluated to see if a device called HeartMate 3 can help their heart function better compared to standard medical treatments.
Recruiting
Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg
N/A Kenosha, Wisconsin NCT07400926
This trial is looking for adults with open-angle glaucoma to evaluate a new tool used for a specific eye implant. Participants will help test how well this new inserter works during the treatment process.
Recruiting

Where the Hypertension studies are in Wisconsin

  • Medical College of Wisconsin, Milwaukee4 trials
  • Aurora St. Luke's Medical Center, Milwaukee2 trials
  • University of Wisconsin Hospital and Clinics, Madison2 trials
  • Advocate Aurora Research Institute, LLC, Milwaukee1 trial
  • Allegiance Research Specialists, Wauwatosa1 trial
  • Aspirus Research Institute, Wausau1 trial

Counts are recruiting studies listing at least one site in Wisconsin, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in Wisconsin: common questions

How many Hypertension clinical trials are recruiting in Wisconsin?
TrialFinder currently lists 18 recruiting Hypertension clinical trials with study sites in Wisconsin. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Wisconsin?
Study sites for the Hypertension trials listed on this page include Milwaukee, Madison, Kenosha. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Wisconsin?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Wisconsin also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Wisconsin?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
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Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

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