34 Recruiting Trials

Clinical Trials
for Hypertension in Georgia

34 clinical trials for Hypertension are currently recruiting participants at study sites in Georgia. Study-related care is provided at no cost.

34
Recruiting trials
73
Study sites
32
Cities
25
Industry-sponsored
10
Phase 2
9
Phase 3

Hypertension clinical trials in Georgia: what to expect

High blood pressure trials focus on people whose pressure stays above target despite treatment. They test new classes of medicine, including once-daily pills and injections given every few months, procedures such as renal denervation for resistant hypertension, and programs built around home monitoring, diet and pharmacist-led care. Many are short, and some require no change to the medicines you already take.

In Georgia, recruiting hypertension studies are concentrated in Atlanta, Columbus, Decatur and Marietta, with sites in 28 other cities. 25 of the 34 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who hypertension trials usually look for

Trials set a blood pressure range measured at the site after rest, often on two separate visits, and state how many medicines you may already take: some want people on none, most want one to three, and resistant hypertension trials want three or more including a diuretic. Common exclusions are a known secondary cause, a recent heart attack or stroke, advanced kidney disease and pregnancy. Ages are usually 18 to 80.

What taking part involves

Screening includes blood pressure measurements, blood work and often a 24-hour wearable monitor. Some trials then standardize or pause your current medicines under supervision, while others add the study drug to them; the listing says which. Drug trials run eight to twelve weeks with visits every two to four weeks and home readings in between; placebo arms are common and rescue rules protect anyone whose pressure climbs. Procedure trials involve a day procedure and longer follow-up. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines change and who monitors you if they do; how the 24-hour monitor works; the chance of placebo and the rescue rules; and whether you keep the study medicine or return to your usual treatment afterwards.

Showing 20 of 34 recruiting Hypertension trials in Georgia

A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
PHASE2 Savannah, Georgia +2 sites NCT07553442
This trial is looking for adults with mild to moderate high blood pressure. Participants will be evaluated to see how well they respond to the treatment after using another medication called zilebesiran.
Recruiting
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
PHASE2 Phoenix, Arizona +4 sites NCT07090161
This trial is looking for people with uncontrolled high blood pressure. Participants will take either the study drug or a placebo to see if it helps lower their blood pressure.
Recruiting
SPYRAL GEMINI Pilot Study
NA Atlanta, Georgia +4 sites NCT06907147
This trial is looking for people with high blood pressure who are between 18 and 80 years old. Participants will receive a treatment aimed at lowering blood pressure.
Recruiting
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
PHASE3 Fresno, California +4 sites NCT06274801
This trial is looking for adults who have completed a previous study with seralutinib. Participants will take seralutinib and be monitored for safety and effectiveness over time.
Recruiting
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
PHASE3 Phoenix, Arizona +4 sites NCT07218029
This trial is looking for people who have completed a previous study with sotatercept for pulmonary arterial hypertension (PAH). Participants will be monitored for the long-term safety and tolerance of sotatercept along with their usual PAH treatments.
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
PHASE3 Alexander City, Alabama +4 sites NCT07288398
This trial is looking for adults with pulmonary hypertension and heart failure. Participants will take either a medication called levosimendan or a placebo to see if it improves their walking distance.
Recruiting
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
PHASE2 Alexander City, Alabama +4 sites NCT07142356
This trial is looking for adults with high blood pressure that is hard to control. Participants will take either the drug RTN-001 or a placebo (a dummy pill) every day for 12 weeks and visit the clinic for checkups.
Recruiting
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
PHASE2 Little Rock, Arkansas +4 sites NCT06343298
This trial is looking for adults aged 18 to 80 who have high blood pressure that is hard to manage. Participants will receive either a treatment called MANP or a placebo to see if it helps lower their blood pressure.
Recruiting
Bioenergetic Effect of Pioglitazone in CLD-PH
PHASE2 Atlanta, Georgia NCT06336798
Recruiting
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
PHASE1 Scottsdale, Arizona +4 sites NCT06649110
This trial is looking for healthy volunteers and patients diagnosed with pulmonary arterial hypertension (PAH). Participants will receive treatment LTP001 and help researchers learn about its effects.
Recruiting
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
NA Atlanta, Georgia +4 sites NCT06526858
This trial is looking for adults aged 22 to 80 with resistant hypertension. Participants will undergo a procedure to evaluate a new renal denervation device while continuing their current blood pressure medications.
Recruiting
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
N/A Birmingham, Alabama +4 sites NCT06388421
This trial is looking for adults with pulmonary hypertension related to interstitial lung disease. Participants will share information about their health and treatments to help improve understanding of these conditions.
Recruiting
Pulmonary Hypertension Association Registry
N/A Phoenix, Arizona +4 sites NCT04071327
This trial is looking for people with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). Participants will provide information about their health and treatment to help improve care for these conditions.
Recruiting
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NA Scottsdale, Arizona +4 sites NCT06059638
This trial is looking for people with high blood pressure who need a pacemaker. Participants will try a new treatment that adjusts heart rhythms to help lower blood pressure.
Recruiting
Technology-enabled Management Versus Usual Care for Blood Pressure
NA Atlanta, Georgia +2 sites NCT05479461
This trial is looking for adults with high blood pressure who own a smartphone. Participants will receive technology-based management to help control their blood pressure.
Recruiting
Global Paradise System US Post Approval Study
N/A Long Beach, California +4 sites NCT06297291
This trial is looking for adults with high blood pressure that isn't controlled by lifestyle changes or medications. Participants will receive treatment with the Paradise Ultrasound Renal Denervation System and help researchers understand its long-term safety and effectiveness.
Recruiting
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
PHASE2 Garden Grove, California +4 sites NCT07543120
This trial is looking for patients with high blood pressure who have completed an earlier study with the QCZ484 medication. Participants will continue to take QCZ484 and help researchers gather more information on its safety and effectiveness.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting

Where the Hypertension studies are in Georgia

  • Coastal Research Associates, LLC, Roswell2 trials
  • Emory University Hospital, Atlanta2 trials
  • Piedmont Heart Institute, Atlanta2 trials
  • Southeastern Cardiology Associates, Columbus2 trials
  • Atlanta Heart Specialists, LLC, Tucker1 trial
  • Atlanta VA Medical Center, Decatur1 trial

Counts are recruiting studies listing at least one site in Georgia, from ClinicalTrials.gov, refreshed every two days.

Hypertension clinical trials in Georgia: common questions

How many Hypertension clinical trials are recruiting in Georgia?
TrialFinder currently lists 34 recruiting Hypertension clinical trials with study sites in Georgia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Hypertension clinical trials located in Georgia?
Study sites for the Hypertension trials listed on this page include Savannah, Atlanta, Columbus. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Hypertension clinical trial in Georgia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Hypertension trials in Georgia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Hypertension clinical trial in Georgia?
Each study sets its own criteria based on age, Hypertension diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will I stop my blood pressure medicine to join a trial?
Some trials add the study drug to what you take; others standardize or pause your medicines for a few weeks under close monitoring, with rules for stepping in if pressure rises. The listing and consent form state which.
What is ambulatory blood pressure monitoring?
A small cuff and monitor worn for 24 hours that records readings automatically, including during sleep. Trials use it because it is more reliable than clinic readings; the site fits it and you return it the next day.
Is a high reading at home enough to qualify?
It is a reason to ask. Trials confirm eligibility with readings taken at the site after resting, usually on two visits, so a single home reading neither qualifies nor rules you out.
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Hypertension trials study novel antihypertensives, renal denervation, lifestyle interventions, and combination therapies for resistant high blood pressure.

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