18 Recruiting Trials

Clinical Trials
for Lupus in Georgia

18 clinical trials for Lupus are currently recruiting participants at study sites in Georgia. Study-related care is provided at no cost.

18
Recruiting trials
17
Study sites
4
Cities
11
Industry-sponsored
7
Phase 2
5
Phase 3

Lupus clinical trials in Georgia: what to expect

Lupus trials are mostly for systemic lupus that stays active despite standard treatment. They test biologic infusions and injections that target the immune signals behind lupus, new oral medicines, and treatments that reduce the need for steroids. Lupus nephritis, where the disease affects the kidneys, has its own trials with their own entry rules, and cell-based therapies are beginning to be tested in people whose lupus has not responded to anything else.

In Georgia, recruiting lupus studies are concentrated in Atlanta, Lawrenceville, Marietta and Gainesville. 11 of the 18 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who lupus trials usually look for

Trials require a confirmed diagnosis with positive antibody tests, active disease above a threshold on a standard activity score at screening, and a stable regimen of your current medicines (an antimalarial, an immunosuppressant, a steroid below a stated dose) for several weeks beforehand. Lupus nephritis trials need a recent kidney biopsy and a protein-in-urine level above a cut-off. Common exclusions are severe active lupus of the brain, a recent biologic, serious infection and pregnancy. Ages are usually 18 to 75.

What taking part involves

Screening includes blood and urine tests and a review of your records. Most trials then last a year with visits every four weeks for an infusion or injection, lab monitoring and a disease-activity exam, often with a plan to taper steroids. The study drug is usually compared with placebo, both added to your existing treatment, and flares are treated as needed. An open-label extension generally follows. All study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines stay unchanged; how the steroid taper works; the chance of placebo and whether an extension follows; what happens during a flare; and what the trial means for pregnancy planning.

Showing 18 of 18 recruiting Lupus trials in Georgia

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
PHASE3 Avondale, Arizona +4 sites NCT06617325
This trial is looking for people aged 16 and older who have moderate to severe systemic lupus erythematosus (SLE) and are not getting enough improvement from their current medications. Participants will receive dapirolizumab pegol as an additional treatment along with their existing medications.
Recruiting
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).
PHASE3 Anniston, Alabama +4 sites NCT06133972
This trial is looking for people with systemic lupus erythematosus who have completed a previous study using ianalumab. Participants will be monitored for long-term safety and tolerance of the treatment.
Recruiting
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
PHASE3 Los Angeles, California +4 sites NCT07332481
This trial is looking for people with skin problems related to lupus. If you join, you'll take a treatment called enpatoran for 24 weeks and have visits every 4 weeks.
Recruiting
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
PHASE3 Beverly Hills, California +4 sites NCT07438496
This trial is looking for adults with moderate to severe lupus. Participants will receive either the drug nipocalimab or a placebo to see how well it works.
Recruiting
Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
PHASE3 Atlanta, Georgia +4 sites NCT05799378
This trial is looking for older adults with lupus who want to see if they can safely stop taking hydroxychloroquine. Participants will be monitored for one year to check their disease activity.
Recruiting
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
PHASE2 Atlanta, Georgia +4 sites NCT05039619
This trial is looking for teenagers aged 12 to 18 and children aged 5 to under 12 who have been diagnosed with lupus nephritis. Participants will receive treatment with obinutuzumab and be monitored for safety and effectiveness.
Recruiting
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
PHASE1 Orange, California +4 sites NCT06121297
This trial is looking for adults with active systemic lupus erythematosus or lupus nephritis. Participants will receive the treatment CABA-201 and will be monitored for safety and effectiveness.
Recruiting
VIBRANT: VIB4920 for Active Lupus Nephritis
PHASE2 La Jolla, California +4 sites NCT05201469
This trial is looking for adults with active lupus nephritis. Participants will take VIB4920 along with other medications to see if it helps improve kidney function.
Recruiting
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
PHASE2 Atlanta, Georgia +4 sites NCT05538208
This trial is looking for young people aged 8 to 20 with lupus nephritis. Participants will take a medication called Mycophenolate Mofetil and visit the study site regularly for assessments.
Recruiting
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
PHASE1 Atlanta, Georgia +4 sites NCT06897930
This trial is looking for adults aged 18 to 70 who have severe systemic lupus erythematosus that hasn’t improved with other treatments. Participants will receive a special therapy called AZD0120 and will be monitored for its safety and effectiveness.
Recruiting
PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
PHASE4 La Mesa, California +4 sites NCT07611214
This trial is looking for adults with lupus nephritis who want to test a new combination treatment. Participants will need to take some specific medications and be within a certain age range.
Recruiting
Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial
PHASE4 Atlanta, Georgia +4 sites NCT07225387
This trial is looking for adults with lupus nephritis to see if a combination of two medications helps improve kidney function. Participants will receive treatments and undergo health assessments over time.
Recruiting
Wellness & Workforce Solution for Lupus/Lupus Nephritis
NA Atlanta, Georgia NCT06217107
This trial is looking for adult women of color who have lupus or lupus nephritis. Participants will receive coaching through a technology app to help improve their health and well-being.
Recruiting
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
N/A La Jolla, California +4 sites NCT07175285
This trial is looking for people with active systemic lupus erythematosus who have not responded well to previous treatments. Participants will need to meet specific health criteria and may undergo assessments to evaluate their condition.
Recruiting
Lupus Landmark Study: A Prospective Registry and Biorepository
N/A Birmingham, Alabama +4 sites NCT05934149
This trial is looking for adults aged 18 or older who have been diagnosed with systemic lupus erythematosus (SLE), including lupus nephritis. Participants will help gather important data and samples for future research.
Recruiting
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
PHASE1 Little Rock, Arkansas +4 sites NCT06557265
This trial is looking for adults with certain autoimmune diseases like lupus nephritis. Participants will receive NKX019 treatment and will need to attend scheduled visits during the study.
Recruiting
A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
PHASE2 Lawrenceville, Georgia +3 sites NCT06419205
This trial is looking for men and women aged 16 and older with IgA Nephropathy, Lupus Nephritis, or C3 Glomerulopathy. Participants will receive the treatment ADX-097 and will need to meet specific health criteria to join.
Recruiting
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
PHASE1 Birmingham, Alabama +4 sites NCT03816345
This trial is looking for adults with advanced cancers who also have autoimmune disorders. Participants will receive treatments that may include the drug nivolumab and possibly others to see how well they work together.
Recruiting

Where the Lupus studies are in Georgia

  • Emory Children's Center, Atlanta2 trials
  • Emory University, Atlanta2 trials
  • Emory University School of Medicine, Atlanta2 trials
  • Parris and Associates Rheumatology, Lawrenceville2 trials
  • Atlanta Research Center for Rheumatology, Marietta1 trial
  • Emory University Hospital/Winship Cancer Institute, Atlanta1 trial

Counts are recruiting studies listing at least one site in Georgia, from ClinicalTrials.gov, refreshed every two days.

Lupus clinical trials in Georgia: common questions

How many Lupus clinical trials are recruiting in Georgia?
TrialFinder currently lists 18 recruiting Lupus clinical trials with study sites in Georgia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Lupus clinical trials located in Georgia?
Study sites for the Lupus trials listed on this page include Atlanta, Lawrenceville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Lupus clinical trial in Georgia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Lupus trials in Georgia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Lupus clinical trial in Georgia?
Each study sets its own criteria based on age, Lupus diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will my regular lupus medicines stop if I join a trial?
No. Lupus trials add the study treatment to a stable regimen of your current medicines. Many include a planned steroid taper as one of the goals, managed by the study doctor.
Is there a placebo in lupus trials?
Usually, but always on top of standard treatment, never instead of it, and most trials move everyone onto the active drug in an extension after the main study period.
Can I join a trial if I have lupus nephritis?
Yes. Lupus nephritis has dedicated trials that require a recent kidney biopsy and a stated level of protein in the urine. General lupus trials often exclude active nephritis, so look for the ones that name it.
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Lupus trials evaluate belimumab, anifrolumab, JAK inhibitors, and other biologics targeting the immune dysregulation behind systemic lupus erythematosus.

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