Lupus Trials / Trials in Arizona
12 Recruiting Trials

Clinical Trials
for Lupus in Arizona

12 clinical trials for Lupus are currently recruiting participants at study sites in Arizona. Study-related care is provided at no cost.

12
Recruiting trials
17
Study sites
7
Cities
9
Industry-sponsored
2
Phase 2
4
Phase 3

Lupus clinical trials in Arizona: what to expect

Lupus trials are mostly for systemic lupus that stays active despite standard treatment. They test biologic infusions and injections that target the immune signals behind lupus, new oral medicines, and treatments that reduce the need for steroids. Lupus nephritis, where the disease affects the kidneys, has its own trials with their own entry rules, and cell-based therapies are beginning to be tested in people whose lupus has not responded to anything else.

In Arizona, recruiting lupus studies are concentrated in Phoenix, Scottsdale, Tucson and Avondale, with sites in 3 other cities. 9 of the 12 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who lupus trials usually look for

Trials require a confirmed diagnosis with positive antibody tests, active disease above a threshold on a standard activity score at screening, and a stable regimen of your current medicines (an antimalarial, an immunosuppressant, a steroid below a stated dose) for several weeks beforehand. Lupus nephritis trials need a recent kidney biopsy and a protein-in-urine level above a cut-off. Common exclusions are severe active lupus of the brain, a recent biologic, serious infection and pregnancy. Ages are usually 18 to 75.

What taking part involves

Screening includes blood and urine tests and a review of your records. Most trials then last a year with visits every four weeks for an infusion or injection, lab monitoring and a disease-activity exam, often with a plan to taper steroids. The study drug is usually compared with placebo, both added to your existing treatment, and flares are treated as needed. An open-label extension generally follows. All study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines stay unchanged; how the steroid taper works; the chance of placebo and whether an extension follows; what happens during a flare; and what the trial means for pregnancy planning.

Showing 12 of 12 recruiting Lupus trials in Arizona

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
PHASE3 Avondale, Arizona +4 sites NCT06617325
This trial is looking for people aged 16 and older who have moderate to severe systemic lupus erythematosus (SLE) and are not getting enough improvement from their current medications. Participants will receive dapirolizumab pegol as an additional treatment along with their existing medications.
Recruiting
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
PHASE3 Phoenix, Arizona +4 sites NCT05835310
This trial is looking for children with moderate to severe systemic lupus erythematosus (SLE) to test a treatment called Anifrolumab. Participants will be monitored to understand how well the treatment works and its safety.
Recruiting
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus
PHASE3 Phoenix, Arizona +4 sites NCT07430306
This trial is looking for adults with systemic lupus erythematosus (SLE) who have not used immunosuppressive drugs before. Participants will receive anifrolumab as an additional treatment to their regular medications for SLE.
Recruiting
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
PHASE2 Phoenix, Arizona +4 sites NCT05268289
This trial is looking for people with active lupus nephritis. Participants will take a medication called LNP023 along with their usual treatment to see how well it works and how safe it is.
Recruiting
Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial
PHASE4 Glendale, Arizona +4 sites NCT07225387
This trial is looking for adults with lupus nephritis to see if a combination of two medications helps improve kidney function. Participants will receive treatments and undergo health assessments over time.
Recruiting
A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
PHASE1 Scottsdale, Arizona +4 sites NCT06576271
This trial is looking for healthy individuals and people with systemic lupus erythematosus (SLE) to evaluate a new treatment. Participants will undergo medical evaluations and may need to provide blood samples.
Recruiting
Lupus Landmark Study: A Prospective Registry and Biorepository
N/A Tucson, Arizona +4 sites NCT05934149
This trial is looking for adults aged 18 or older who have been diagnosed with systemic lupus erythematosus (SLE), including lupus nephritis. Participants will help gather important data and samples for future research.
Recruiting
Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment
PHASE3 Phoenix, Arizona +4 sites NCT07691970
This trial is looking for people who have finished another study with anifrolumab and are still benefiting from it. Participants will continue to receive anifrolumab and will be monitored for safety.
Recruiting
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
PHASE2 Scottsdale, Arizona +4 sites NCT06570798
This trial is looking for adults with systemic lupus erythematosus or rheumatoid arthritis. Participating involves receiving treatment with inebilizumab or blinatumomab and attending follow-up visits to monitor your health.
Recruiting
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
PHASE1 Phoenix, Arizona +4 sites NCT07085104
This trial is looking for adults between 18 and 75 years old who have active autoimmune diseases like lupus, myopathy, or scleroderma that haven't responded well to standard treatments. They also want to make sure participants are generally healthy and don’t have serious infections or certain other health issues, like recent heart problems or cancer. If someone has had certain types of previous treatments or has unstable health, they wouldn’t be able to join.
Recruiting
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
PHASE1 Avondale, Arizona +4 sites NCT06613360
This trial is looking for patients with Moderate to Severe Systemic Lupus Erythematosus (SLE) who have not responded well to previous treatments. Participants will receive a medication called CLN-978 through a subcutaneous injection.
Recruiting
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
NA Phoenix, Arizona +4 sites NCT05612750
This trial is looking for adults with chronic pain to compare two different treatments: an 8-week program of cognitive behavioral therapy and a one-time pain relief skills session. Participants will either take part in the longer therapy or the shorter session.
Recruiting
See all 12 Lupus trials in Arizona

Where the Lupus studies are in Arizona

Research sites running the most studies
  • Research Site, Phoenix3 trials
  • AARA Clinical Research, Avondale1 trial
  • AARA Clinical Research, Tucson1 trial
  • AARA Clinical Research, Glendale1 trial
  • AKDHC Medical Research ServicesLLC, Phoenix1 trial
  • GSK Investigational Site, Scottsdale1 trial
By city

Counts are recruiting studies listing at least one site in Arizona, from ClinicalTrials.gov, refreshed every two days.

Lupus clinical trials in Arizona: common questions

How many Lupus clinical trials are recruiting in Arizona?
TrialFinder currently lists 12 recruiting Lupus clinical trials with study sites in Arizona. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Lupus clinical trials located in Arizona?
Study sites for the Lupus trials listed on this page include Avondale, Phoenix, Glendale, Scottsdale, Tucson. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Lupus clinical trial in Arizona?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Lupus trials in Arizona also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Lupus clinical trial in Arizona?
Each study sets its own criteria based on age, Lupus diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will my regular lupus medicines stop if I join a trial?
No. Lupus trials add the study treatment to a stable regimen of your current medicines. Many include a planned steroid taper as one of the goals, managed by the study doctor.
Is there a placebo in lupus trials?
Usually, but always on top of standard treatment, never instead of it, and most trials move everyone onto the active drug in an extension after the main study period.
Can I join a trial if I have lupus nephritis?
Yes. Lupus nephritis has dedicated trials that require a recent kidney biopsy and a stated level of protein in the urine. General lupus trials often exclude active nephritis, so look for the ones that name it.
Lupus Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Lupus Trials

Lupus trials evaluate belimumab, anifrolumab, JAK inhibitors, and other biologics targeting the immune dysregulation behind systemic lupus erythematosus.

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Other Conditions in Arizona
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