9 Recruiting Trials

Clinical Trials
for Lupus in Utah

9 clinical trials for Lupus are currently recruiting participants at study sites in Utah. Study-related care is provided at no cost.

9
Recruiting trials
7
Study sites
1
City
3
Industry-sponsored
2
Phase 2
1
Phase 3

Lupus clinical trials in Utah: what to expect

Lupus trials are mostly for systemic lupus that stays active despite standard treatment. They test biologic infusions and injections that target the immune signals behind lupus, new oral medicines, and treatments that reduce the need for steroids. Lupus nephritis, where the disease affects the kidneys, has its own trials with their own entry rules, and cell-based therapies are beginning to be tested in people whose lupus has not responded to anything else.

In Utah, recruiting lupus studies are concentrated in Salt Lake City. 3 of the 9 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who lupus trials usually look for

Trials require a confirmed diagnosis with positive antibody tests, active disease above a threshold on a standard activity score at screening, and a stable regimen of your current medicines (an antimalarial, an immunosuppressant, a steroid below a stated dose) for several weeks beforehand. Lupus nephritis trials need a recent kidney biopsy and a protein-in-urine level above a cut-off. Common exclusions are severe active lupus of the brain, a recent biologic, serious infection and pregnancy. Ages are usually 18 to 75.

What taking part involves

Screening includes blood and urine tests and a review of your records. Most trials then last a year with visits every four weeks for an infusion or injection, lab monitoring and a disease-activity exam, often with a plan to taper steroids. The study drug is usually compared with placebo, both added to your existing treatment, and flares are treated as needed. An open-label extension generally follows. All study care is free and visits are usually paid.

Questions worth asking the study team

Whether your current medicines stay unchanged; how the steroid taper works; the chance of placebo and whether an extension follows; what happens during a flare; and what the trial means for pregnancy planning.

Showing 9 of 9 recruiting Lupus trials in Utah

Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)
NA Salt Lake City, Utah NCT07282392
This trial is looking for adults with lupus and fibromyalgia. Participants will attend 8 weekly therapy sessions online to help manage their pain and symptoms.
Recruiting
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
PHASE3 Phoenix, Arizona +4 sites NCT05835310
This trial is looking for children with moderate to severe systemic lupus erythematosus (SLE) to test a treatment called Anifrolumab. Participants will be monitored to understand how well the treatment works and its safety.
Recruiting
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
PHASE2 San Francisco, California +4 sites NCT05538208
This trial is looking for young people aged 8 to 20 with lupus nephritis. Participants will take a medication called Mycophenolate Mofetil and visit the study site regularly for assessments.
Recruiting
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
N/A Chicago, Illinois +4 sites NCT00198068
This trial is looking for pregnant women with systemic lupus erythematosus or antiphospholipid syndrome to understand how certain proteins may affect pregnancy outcomes. Participants will be monitored throughout their pregnancy to see if these proteins can predict complications.
Recruiting
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
PHASE1 Phoenix, Arizona +4 sites NCT07085104
This trial is looking for adults between 18 and 75 years old who have active autoimmune diseases like lupus, myopathy, or scleroderma that haven't responded well to standard treatments. They also want to make sure participants are generally healthy and don’t have serious infections or certain other health issues, like recent heart problems or cancer. If someone has had certain types of previous treatments or has unstable health, they wouldn’t be able to join.
Recruiting
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
PHASE1 Avondale, Arizona +4 sites NCT06613360
This trial is looking for patients with Moderate to Severe Systemic Lupus Erythematosus (SLE) who have not responded well to previous treatments. Participants will receive a medication called CLN-978 through a subcutaneous injection.
Recruiting
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
NA Salt Lake City, Utah +4 sites NCT05612750
This trial is looking for adults with chronic pain to compare two different treatments: an 8-week program of cognitive behavioral therapy and a one-time pain relief skills session. Participants will either take part in the longer therapy or the shorter session.
Recruiting
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
PHASE2 Salt Lake City, Utah +2 sites NCT03152058
This trial is looking for pregnant women who have antiphospholipid syndrome and positive tests for lupus anticoagulant. Participants will receive certolizumab in addition to their usual treatments to see if it improves their pregnancy outcomes.
Recruiting
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
PHASE1 Birmingham, Alabama +4 sites NCT03816345
This trial is looking for adults with advanced cancers who also have autoimmune disorders. Participants will receive treatments that may include the drug nivolumab and possibly others to see how well they work together.
Recruiting

Where the Lupus studies are in Utah

  • University of Utah, Salt Lake City3 trials
  • Huntsman Cancer Institute/University of Utah, Salt Lake City1 trial
  • Intermountain Health, Salt Lake City1 trial
  • Intermountain Healthcare, Salt Lake City1 trial
  • LDS Hospital - lntermountain Health, Salt Lake City1 trial
  • Research Site, Salt Lake City1 trial

Counts are recruiting studies listing at least one site in Utah, from ClinicalTrials.gov, refreshed every two days.

Lupus clinical trials in Utah: common questions

How many Lupus clinical trials are recruiting in Utah?
TrialFinder currently lists 9 recruiting Lupus clinical trials with study sites in Utah. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Lupus clinical trials located in Utah?
Study sites for the Lupus trials listed on this page include Salt Lake City. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Lupus clinical trial in Utah?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Lupus trials in Utah also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Lupus clinical trial in Utah?
Each study sets its own criteria based on age, Lupus diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Will my regular lupus medicines stop if I join a trial?
No. Lupus trials add the study treatment to a stable regimen of your current medicines. Many include a planned steroid taper as one of the goals, managed by the study doctor.
Is there a placebo in lupus trials?
Usually, but always on top of standard treatment, never instead of it, and most trials move everyone onto the active drug in an extension after the main study period.
Can I join a trial if I have lupus nephritis?
Yes. Lupus nephritis has dedicated trials that require a recent kidney biopsy and a stated level of protein in the urine. General lupus trials often exclude active nephritis, so look for the ones that name it.
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Lupus trials evaluate belimumab, anifrolumab, JAK inhibitors, and other biologics targeting the immune dysregulation behind systemic lupus erythematosus.

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