Depression Trials / Trials in Utah
12 Recruiting Trials

Clinical Trials
for Depression in Utah

12 clinical trials for Depression are currently recruiting participants at study sites in Utah. Study-related care is provided at no cost.

12
Recruiting trials
11
Study sites
6
Cities
7
Industry-sponsored
4
Phase 2
2
Phase 3

Depression clinical trials in Utah: what to expect

Depression trials cover new medicines, brain stimulation, talk therapy and digital programs. The busiest area is treatment-resistant depression: studies for people whose current antidepressant has not helped enough, testing rapid-acting medicines, add-on treatments and devices such as transcranial magnetic stimulation. Others compare types of therapy, test app-based programs, or study depression alongside another condition such as chronic pain or heart disease.

In Utah, recruiting depression studies are concentrated in Salt Lake City, Draper, Bountiful and Clinton, with sites in 2 other cities. 7 of the 12 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who depression trials usually look for

Most adult trials require a diagnosis of major depressive disorder, a current episode with symptoms above a threshold on a standard questionnaire, and ages 18 to 65. Treatment-resistant trials ask that one or two antidepressants at a proper dose have not worked in the current episode. Common exclusions are bipolar disorder, psychosis, a substance use disorder in the last year and, for safety, a high current suicide risk. Many trials let you continue stable talk therapy.

Some medicine trials add the study drug to the antidepressant you take; others require a supervised taper first. The listing says which.

What taking part involves

Screening is a structured interview with a clinician plus blood work. Medicine trials usually run six to twelve weeks with weekly or fortnightly visits and mood questionnaires, and many include a placebo arm, with close safety monitoring either way; an open-label extension often follows so everyone can receive the active drug. Therapy and app trials run eight to sixteen weeks and compare against usual care. Treatment, visits and tests are free, and most trials pay for time.

Questions worth asking the study team

Whether you would taper your current medicine and how that is supervised; the chance of placebo and whether there is an open-label extension; what happens if you feel worse during the study; and whether your own doctor is kept informed. Research records are kept separate from your medical record unless you ask otherwise.

Showing 12 of 12 recruiting Depression trials in Utah

Brexanolone Lifting Outcomes Of Moms
PHASE3 Tucson, Arizona +4 sites NCT07822321
This trial is looking for women aged 15 to 45 who are experiencing severe postpartum depression. Participants will take the study drug LPCN 1154A to see if it helps reduce their depressive symptoms and to learn about any side effects.
Recruiting
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
PHASE2 Tucson, Arizona +4 sites NCT06524830
This trial is looking for adults with treatment resistant depression. Participants will receive either a new treatment called VLS-01 Buccal Film or a placebo to see how effective it is.
Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
NA Birmingham, Alabama +4 sites NCT03887715
This trial is looking for adults with treatment-resistant depression. Participants will receive either active VNS therapy or a control without stimulation to see how it affects their depression over 12 months.
Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
NA Birmingham, Alabama +4 sites NCT06423430
This trial is looking for adults with treatment resistant depression who have not improved with other treatments. Participants will receive a new type of brain stimulation as part of their care.
Recruiting
Maternal Mental Health Access - MaMa
NA Salt Lake City, Utah NCT06049433
This trial is looking for pregnant and postpartum women at risk for depression. Participants will engage in a remote mindfulness program linked to their healthcare that aims to help improve their mental health.
Recruiting
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
PHASE3 Bentonville, Arkansas +4 sites NCT04777357
This trial is looking for young people aged 10 to 17 who have bipolar I disorder and are experiencing depressive episodes. Participants will receive either a study drug called cariprazine or a placebo to see how it affects their mood.
Recruiting
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
PHASE1 Salt Lake City, Utah +1 sites NCT06767566
This trial is looking for women who have just had a cesarean delivery and are experiencing pain or postpartum depression. Participants will receive ketamine infusions to help understand how it works in their body compared to others.
Recruiting
ALTO-100 in Bipolar Disorder With Depression (BD-D)
PHASE2 Birmingham, Alabama +4 sites NCT06656416
This trial is looking for adults who have bipolar disorder along with a current major depressive episode and are already taking a mood stabilizer. It’s important that they haven't changed their medication in the last two weeks and are not pregnant or breastfeeding. They can't have other serious health issues, be currently using certain medications, or have a history of severe substance use problems.
Recruiting
5-HTP and Creatine for Depression R33 Phase
PHASE2 Salt Lake City, Utah NCT05895747
This trial is looking for adults with major depression to study the effects of two supplements, 5-HTP and creatine. Participants will take these supplements or a placebo for 8 weeks and undergo some brain imaging and blood tests.
Recruiting
Mechanisms of Rumination Change in Adolescent Depression
NA Salt Lake City, Utah +2 sites NCT03859297
This trial is looking for teenagers aged 14-17 with a history of depression. Participants will receive a new type of therapy that helps change negative thinking patterns, aiming to reduce the chances of depression returning.
Recruiting
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
PHASE2 Phoenix, Arizona +4 sites NCT07621237
This trial is looking for adults with major depressive disorder to see if a new treatment called TNX-102 SL helps improve their symptoms. Participants will take the treatment or a placebo for 6 weeks and visit the clinic every two weeks for checkups.
Recruiting
Evaluation of the H.O.O.V.E.S. Healing Intensives Program
N/A Salt Lake City, Utah NCT06300255
This trial is looking for Veterans who want to improve their mental health through the H.O.O.V.E.S. healing program. Participants will fill out surveys before, during, and after the program to see how it helps them.
Recruiting
See all 12 Depression trials in Utah

Where the Depression studies are in Utah

Research sites running the most studies
  • University of Utah, Salt Lake City3 trials
  • Boeson Research Pvu, Provo1 trial
  • Cedar Clinical Research Inc, Draper1 trial
  • George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City1 trial
  • Lipocine Investigational Site, Clinton1 trial
  • Lipocine Investigational Site, Orem1 trial
By city

Counts are recruiting studies listing at least one site in Utah, from ClinicalTrials.gov, refreshed every two days.

Depression clinical trials in Utah: common questions

How many Depression clinical trials are recruiting in Utah?
TrialFinder currently lists 12 recruiting Depression clinical trials with study sites in Utah. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Depression clinical trials located in Utah?
Study sites for the Depression trials listed on this page include Salt Lake City. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Depression clinical trial in Utah?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Depression trials in Utah also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Depression clinical trial in Utah?
Each study sets its own criteria based on age, Depression diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I have to stop my antidepressant to join a depression trial?
Not always. Many trials add the study treatment to the antidepressant you already take; others ask for a supervised taper before starting. Each listing states which, and the study doctor manages any change.
Is there a placebo in depression trials?
Most medicine trials include a placebo arm, often with two active participants for every one on placebo, and usually followed by an extension where everyone receives the drug. Therapy, device and app trials generally compare against usual care instead.
Can I join if I am already seeing a therapist?
Usually yes for medicine trials, provided the therapy has been ongoing and stable. Trials of a specific therapy may ask you not to start a second one during the study.
Depression Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Depression Trials

Depression trials investigate antidepressant medications, TMS, ketamine infusions, psychotherapy protocols, and digital mental-health interventions.

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