504 Recruiting Trials

Clinical Trials for Depression

Depression trials investigate antidepressant medications, TMS, ketamine infusions, psychotherapy protocols, and digital mental-health interventions.

Showing 15 of 504 recruiting trials

PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
PHASE3 Milford, Connecticut +4 more NCT06713616
Recruiting
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
PHASE3 Birmingham, Alabama +4 more NCT06793397
Recruiting
E-Mindfulness Approaches for Living After Breast Cancer
PHASE3 Phoenix, Arizona +4 more NCT06748222
Recruiting
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
PHASE3 Bentonville, Arkansas +4 more NCT04777357
Recruiting
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
PHASE2 Houston, Texas NCT05474846
Recruiting
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
PHASE2 San Diego, California NCT06273527
Recruiting
Creatine for Depressed Male and Female Methamphetamine Users
PHASE3 Missoula, Montana NCT02568878
Recruiting
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
PHASE2 Bethesda, Maryland NCT06511908
Recruiting
A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression
PHASE1 Chelsea, Massachusetts NCT06597695
Recruiting
Neurobiology of Suicide
PHASE2 Bethesda, Maryland NCT02543983
Recruiting
Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II
PHASE2 St Louis, Missouri NCT06867549
Recruiting
A Digital Intervention for Post-Stroke Depression and Executive Dysfunction
PHASE2 New York, New York NCT05507138
Recruiting
Psilocybin-Assisted Therapy for Intergenerational Trauma
PHASE2 New York, New York NCT06899165
Recruiting
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
PHASE2 Houston, Texas NCT06801041
Recruiting
Apimostinel + Automated Neurocognitive Training for Depression
PHASE2 Pittsburgh, Pennsylvania NCT06400121
Recruiting
See all 504 results
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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