340 Recruiting Trials

Clinical Trials
for Anxiety

Anxiety disorder trials study CBT approaches, novel anxiolytics, MDMA-assisted therapy, and neuromodulation techniques for GAD, social anxiety, and PTSD.

Anxiety clinical trials: what to expect

Anxiety trials study generalized anxiety disorder, social anxiety, panic disorder and often post-traumatic stress alongside them. The treatments under study range from new medicines and repurposed ones to cognitive behavioral therapy delivered in person, by video or through an app, virtual-reality exposure, and brain stimulation. Many are run by universities and some can be completed largely online, with a small number of in-person visits.

Who anxiety trials usually look for

Trials name the diagnosis they study and set a minimum symptom score on a standard questionnaire, confirmed by a clinician interview at screening. Adults 18 to 65 are the usual range, with separate studies for teenagers and older adults. Typical exclusions are bipolar disorder, psychosis, a current substance use disorder and, for some medicine trials, daily benzodiazepine use. Stable antidepressant treatment is often allowed.

What taking part involves

After a screening interview, medicine trials run eight to twelve weeks with visits every one to two weeks, questionnaires and sometimes blood work; placebo arms are common. Therapy trials involve weekly sessions for eight to sixteen weeks, often with a comparison group that gets the program later. Some studies add brain imaging or a wearable to track sleep and heart rate. Everything study-related is free, and most trials pay for your time.

Questions worth asking the study team

Which visits must be in person; whether you can continue your current medicine or therapy; the chance of placebo or of a waiting-list group; and what support is available if symptoms get worse during the study.

Showing 15 of 340 recruiting trials

Buspirone for Anxiety in Autistic Youth
PHASE4 Lexington, Massachusetts NCT07439042
Recruiting
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
PHASE4 Cincinnati, Ohio NCT04623099
Recruiting
Preoperative Music Intervention for Anxiety in Hip and Knee Arthroplasty
NA New York, New York NCT07845695
Recruiting
Impact of Virtual Reality on Anxiety in Patients Undergoing Interventional Procedures
NA Chicago, Illinois NCT05744336
Recruiting
VITAL - Virginia Tech Accelerated Holographic LIFU for Anxiety
NA Roanoke, Virginia NCT07404878
Recruiting
Video Game Play to Alleviate Adolescent Anxiety
NA Miami, Florida +2 more NCT05923944
Recruiting
Impact of Art Therapy on Self-Reported Pain and Anxiety Scores of Patients Waiting to Be Seen in the Emergency Department
NA Stony Brook, New York NCT05540106
Recruiting
Anxiety Skills Study
NA Columbus, Ohio NCT07774481
Recruiting
Grow With Grit: A School Nurse-Led SBIRT Pilot for Early Anxiety Detection
NA Great Falls, Montana +3 more NCT07766785
Recruiting
Developing Resilience and Anxiety Management Through the Arts
NA Cleveland, Ohio NCT07033052
Recruiting
Intraoperative Music Therapy in TAVR Patients
NA Providence, Rhode Island NCT07591922
Recruiting
FlowMD Feasibility Study
NA Portland, Oregon NCT07672925
Recruiting
Process-Based Approach Case Series For Anxiety Problems
NA Birmingham, Alabama NCT07352592
Recruiting
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
NA Tallahassee, Florida +2 more NCT05748613
Recruiting
Prediction of Anxiety and Memory State
NA New York, New York NCT06551090
Recruiting
See all 340 results

Anxiety clinical trials by state

Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming

Questions about Anxiety clinical trials

How many clinical trials are available for Anxiety?
TrialFinder currently lists 340 recruiting clinical trials for Anxiety. Listings are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Are Anxiety clinical trials free to participate in?
Study-related care is provided at no cost to participants. The sponsor covers the study treatment, required lab tests, imaging and study visits, and many trials also pay for time and travel. You do not need health insurance to enroll.
How do I qualify for a Anxiety clinical trial?
Each trial sets its own criteria based on age, diagnosis, prior treatment, current medications and general health. The fastest way to find out is to contact the study site: most will pre-screen you by phone in 10 to 15 minutes at no charge.
How do I find Anxiety clinical trials near me?
Pick your state below to see recruiting Anxiety trials there with their sites and cities, or search by city or zip code. Results show actively recruiting trials sorted by distance.
Can I take part in an anxiety trial if I am already in therapy?
Often yes for medicine trials, if the therapy is ongoing and stable. Trials testing a therapy usually ask that you are not starting another one at the same time. The listing states its rule.
Are there anxiety studies I can do online?
Yes. Many app-based and video-therapy studies are mostly remote, though most still need one or two in-person visits, so distance to the site still matters.
Is there a placebo in anxiety trials?
Medicine trials usually include a placebo arm and say so in the consent form. Therapy trials compare against usual care or a group that receives the program after a delay.
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to trials you may qualify for.

Get Matched — Free
No insurance required
Browse by Condition
Diabetes Cancer Breast Cancer Depression Anxiety Alzheimer's Heart Disease Asthma Multiple Sclerosis Obesity Parkinson's Lupus Hypertension COPD Stroke Arthritis Kidney Disease COVID-19
Anxiety Trials by State
California Texas New York Florida Illinois Pennsylvania Ohio Georgia North Carolina Michigan New Jersey Washington Arizona Massachusetts Tennessee Colorado Minnesota Maryland Wisconsin Oregon