Anxiety Trials / Trials in Illinois
15 Recruiting Trials

Clinical Trials
for Anxiety in Illinois

15 clinical trials for Anxiety are currently recruiting participants at study sites in Illinois. Study-related care is provided at no cost.

15
Recruiting trials
12
Study sites
4
Cities
3
Industry-sponsored
2
Phase 2

Anxiety clinical trials in Illinois: what to expect

Anxiety trials study generalized anxiety disorder, social anxiety, panic disorder and often post-traumatic stress alongside them. The treatments under study range from new medicines and repurposed ones to cognitive behavioral therapy delivered in person, by video or through an app, virtual-reality exposure, and brain stimulation. Many are run by universities and some can be completed largely online, with a small number of in-person visits.

In Illinois, recruiting anxiety studies are concentrated in Chicago, Evanston, Lake Forest and Winfield. 3 of the 15 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who anxiety trials usually look for

Trials name the diagnosis they study and set a minimum symptom score on a standard questionnaire, confirmed by a clinician interview at screening. Adults 18 to 65 are the usual range, with separate studies for teenagers and older adults. Typical exclusions are bipolar disorder, psychosis, a current substance use disorder and, for some medicine trials, daily benzodiazepine use. Stable antidepressant treatment is often allowed.

What taking part involves

After a screening interview, medicine trials run eight to twelve weeks with visits every one to two weeks, questionnaires and sometimes blood work; placebo arms are common. Therapy trials involve weekly sessions for eight to sixteen weeks, often with a comparison group that gets the program later. Some studies add brain imaging or a wearable to track sleep and heart rate. Everything study-related is free, and most trials pay for your time.

Questions worth asking the study team

Which visits must be in person; whether you can continue your current medicine or therapy; the chance of placebo or of a waiting-list group; and what support is available if symptoms get worse during the study.

Showing 15 of 15 recruiting Anxiety trials in Illinois

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
PHASE2 Birmingham, Alabama +4 sites NCT07489651
This trial is looking for people with Generalized Anxiety Disorder (GAD) to see if a single injection of RE104 can help reduce their anxiety symptoms. Participants will be compared to those receiving a placebo, which is an inactive treatment.
Recruiting
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
PHASE2 Huntsville, Alabama +4 sites NCT06846320
This trial is looking for adults with generalized anxiety disorder (GAD) who have not had enough relief from their current antidepressant medications. Participants will take capsules of either ABBV-932 or a placebo for 6 weeks, along with their existing treatment, and attend regular check-up visits to monitor their progress.
Recruiting
Device for Treating Generalized Anxiety
NA Chicago, Illinois +2 sites NCT07819773
This trial is looking for adults aged 22 and older with Generalized Anxiety Disorder (GAD) to see if a special device can help reduce their anxiety. Participants will attend 8 treatment sessions over about 4 weeks and answer some questionnaires about their anxiety.
Recruiting
Sleep, Dreaming, and Virtual Reality for Mental Health
EARLY_PHASE1 Evanston, Illinois +1 sites NCT07408206
This trial is looking for people interested in a program that combines waking and dreaming practices to help with mental health, especially anxiety. Participants will use virtual reality and sleep technology to engage in this program and will be monitored for changes in sleep and cognition.
Recruiting
Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss
NA Chicago, Illinois NCT07073521
This trial is looking for adults dealing with vision loss who want to improve their adjustment to this change. Participants will join focus groups and therapy sessions to share their experiences and receive support.
Recruiting
Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music
NA Chicago, Illinois NCT07775625
This trial is looking for people with Alzheimer's disease and anxiety, along with their caregivers. Participants will take part in music sessions designed to help reduce anxiety or listen to calming stories over four weeks.
Recruiting
Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors
NA Chicago, Illinois NCT07290543
This trial is looking for older adults living in rural areas who have experienced cancer-related emotional distress. Participants will use a web-based toolkit to help manage their anxiety and emotional challenges after cancer treatment.
Recruiting
Psychological Prehabilitation for Complex Gastrointestinal Surgery
NA Chicago, Illinois NCT07865052
Recruiting
CommunityRx-Dementia + Peer Navigation (CRxDpeer)
NA Chicago, Illinois NCT07346183
Recruiting
Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury
NA Chicago, Illinois NCT07224165
This trial is looking for teenagers aged 14 to 18 who have harmed themselves without wanting to end their life and are not currently getting mental health treatment. Participants will use a digital app either on their own or with educational content provided.
Recruiting
My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life
NA Chicago, Illinois NCT05369429
This trial is looking for cancer patients over 18 who have symptoms of depression. Participating includes using an online program that offers resources for managing stress over 7 weeks and completing some follow-up assessments.
Recruiting
Test of Target Engagement of Ambiguity Aversion
NA Chicago, Illinois NCT06962527
This trial is looking for adults aged 25 to 60 who experience anxiety and intolerance of uncertainty. Participants will take part in a single session aimed at improving decision-making in uncertain situations.
Recruiting
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
NA Chicago, Illinois NCT06261463
This trial is looking for refugee families living in Chicago for less than three years. Participants will join a group intervention aimed at improving family support and mental health.
Recruiting
Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial
NA Lake Forest, Illinois +2 sites NCT06365723
This trial is looking for adults with prediabetes to compare the effects of walking in nature versus urban areas. Participants will walk for 150 minutes each week for six weeks in both settings and visit the clinic several times for health checks and saliva samples.
Recruiting
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
NA Evanston, Illinois NCT07641244
This trial is looking for families with children aged 5 to 14 whose parents are part of a specific income support program. Participants will receive either a larger or smaller monthly income supplement for three years to see how it affects the child's mental health.
Recruiting
See all 15 Anxiety trials in Illinois

Where the Anxiety studies are in Illinois

Research sites running the most studies
  • Northwestern University, Chicago4 trials
  • Northwestern University, Evanston2 trials
  • Central DuPage Hospital, Winfield1 trial
  • Lake Forest Hospital, Lake Forest1 trial
  • Northwestern Memorial Hospital, Chicago1 trial
  • Northwestern University Feinberg School of Medicine, Chicago1 trial
By city

Counts are recruiting studies listing at least one site in Illinois, from ClinicalTrials.gov, refreshed every two days.

Anxiety clinical trials in Illinois: common questions

How many Anxiety clinical trials are recruiting in Illinois?
TrialFinder currently lists 15 recruiting Anxiety clinical trials with study sites in Illinois. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Anxiety clinical trials located in Illinois?
Study sites for the Anxiety trials listed on this page include Chicago, Evanston, Lake Forest. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Anxiety clinical trial in Illinois?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Anxiety trials in Illinois also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Anxiety clinical trial in Illinois?
Each study sets its own criteria based on age, Anxiety diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I take part in an anxiety trial if I am already in therapy?
Often yes for medicine trials, if the therapy is ongoing and stable. Trials testing a therapy usually ask that you are not starting another one at the same time. The listing states its rule.
Are there anxiety studies I can do online?
Yes. Many app-based and video-therapy studies are mostly remote, though most still need one or two in-person visits, so distance to the site still matters.
Is there a placebo in anxiety trials?
Medicine trials usually include a placebo arm and say so in the consent form. Therapy trials compare against usual care or a group that receives the program after a delay.
Anxiety Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Anxiety Trials

Anxiety disorder trials study CBT approaches, novel anxiolytics, MDMA-assisted therapy, and neuromodulation techniques for GAD, social anxiety, and PTSD.

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