24 Recruiting Trials

Clinical Trials
for Anxiety in Ohio

24 clinical trials for Anxiety are currently recruiting participants at study sites in Ohio. Study-related care is provided at no cost.

24
Recruiting trials
23
Study sites
7
Cities
5
Industry-sponsored
6
Phase 2

Anxiety clinical trials in Ohio: what to expect

Anxiety trials study generalized anxiety disorder, social anxiety, panic disorder and often post-traumatic stress alongside them. The treatments under study range from new medicines and repurposed ones to cognitive behavioral therapy delivered in person, by video or through an app, virtual-reality exposure, and brain stimulation. Many are run by universities and some can be completed largely online, with a small number of in-person visits.

In Ohio, recruiting anxiety studies are concentrated in Columbus, Cincinnati, Cleveland and North Canton, with sites in 3 other cities. 5 of the 24 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who anxiety trials usually look for

Trials name the diagnosis they study and set a minimum symptom score on a standard questionnaire, confirmed by a clinician interview at screening. Adults 18 to 65 are the usual range, with separate studies for teenagers and older adults. Typical exclusions are bipolar disorder, psychosis, a current substance use disorder and, for some medicine trials, daily benzodiazepine use. Stable antidepressant treatment is often allowed.

What taking part involves

After a screening interview, medicine trials run eight to twelve weeks with visits every one to two weeks, questionnaires and sometimes blood work; placebo arms are common. Therapy trials involve weekly sessions for eight to sixteen weeks, often with a comparison group that gets the program later. Some studies add brain imaging or a wearable to track sleep and heart rate. Everything study-related is free, and most trials pay for your time.

Questions worth asking the study team

Which visits must be in person; whether you can continue your current medicine or therapy; the chance of placebo or of a waiting-list group; and what support is available if symptoms get worse during the study.

Showing 20 of 24 recruiting Anxiety trials in Ohio

Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
PHASE4 Cincinnati, Ohio NCT04623099
This trial is looking for young people ages 12 to 17 with anxiety disorders. Participants will receive a type of medication called escitalopram, either in a standard dose or one adjusted based on genetic testing, over 12 weeks.
Recruiting
Anxiety Skills Study
NA Columbus, Ohio NCT07774481
This trial is looking for people with high levels of anxiety living in Ohio. Participants will take part in skill training through videos or therapy sessions, and their progress will be checked over a year.
Recruiting
Developing Resilience and Anxiety Management Through the Arts
NA Cleveland, Ohio NCT07033052
This trial is looking for children and teenagers aged 8 to 17 who have high levels of anxiety or depression. Participants will engage in exercises combining arts and therapy to help manage their feelings.
Recruiting
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
NA Athens, Ohio +2 sites NCT05748613
This trial is looking for older adults with mild Alzheimer's or mild cognitive impairment and their care partners. Participants will attend in-person visits and complete assessments to see if the treatment helps with anxiety.
Recruiting
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
PHASE2 Glendale, California +4 sites NCT06480383
This trial is looking for adults with Generalized Anxiety Disorder (GAD) who have not responded well to their current GAD treatment. Participants will take a new medication, ITI-1284, alongside their ongoing treatment.
Recruiting
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
PHASE2 Birmingham, Alabama +4 sites NCT06701903
This trial is looking for people with moderate or severe generalized anxiety disorder (GAD) who haven't responded well to previous treatments. Participants will take ITI-1284 and help researchers understand its effects on anxiety.
Recruiting
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
PHASE2 Birmingham, Alabama +4 sites NCT07489651
This trial is looking for people with Generalized Anxiety Disorder (GAD) to see if a single injection of RE104 can help reduce their anxiety symptoms. Participants will be compared to those receiving a placebo, which is an inactive treatment.
Recruiting
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
PHASE2 Huntsville, Alabama +4 sites NCT06846320
This trial is looking for adults with generalized anxiety disorder (GAD) who have not had enough relief from their current antidepressant medications. Participants will take capsules of either ABBV-932 or a placebo for 6 weeks, along with their existing treatment, and attend regular check-up visits to monitor their progress.
Recruiting
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
PHASE2 Sherman Oaks, California +4 sites NCT06809179
This trial is looking for adults aged 18 to 65 who have social anxiety disorder. Participants will use a nasal spray to help relieve anxiety symptoms caused by public speaking challenges.
Recruiting
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
PHASE4 Cincinnati, Ohio NCT04221997
This trial is looking for young people ages 8 to 17 who have anxiety disorders like generalized, separation, or social anxiety. Participants will take a medication called sertraline and help researchers understand how it works.
Recruiting
Uncertainty and Firearms: Obtaining Secure Storage
NA Columbus, Ohio NCT05818696
This trial is looking for active duty servicemembers or veterans who want to improve firearm storage practices. Participants will attend two therapy sessions and answer brief surveys each day for 28 days.
Recruiting
Restrained vs Gripping String Techniques in Patients Undergoing Cesarean Delivery
NA Columbus, Ohio NCT07772219
This trial is looking for women who are having a cesarean delivery and want to help compare two different ways of securing their arms during surgery. Participants will be randomly assigned to one of the two techniques and will provide feedback about their anxiety and comfort during the procedure.
Recruiting
A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety
PHASE2 Columbus, Ohio NCT06820723
This trial is looking for adults aged 21 to 65 who have depression and anxiety. Participants will take either a psilocybin-related drug or a placebo and undergo assessments to understand the effects on their symptoms and brain function.
Recruiting
Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety
NA Columbus, Ohio NCT07717541
This trial is looking for adults with anxiety and depression who also have digestive symptoms. Participants will take part in online poetry workshops to express their feelings and improve their well-being.
Recruiting
Weighted Blanket Use to Reduce Anxiety in Oncology Patients
NA Columbus, Ohio NCT06089408
This trial is looking for cancer patients who are about to start chemotherapy. Participants will use a weighted blanket to see if it helps reduce anxiety during their treatment infusions.
Recruiting
Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery
NA Columbus, Ohio NCT06949943
This trial is looking for patients scheduled for cancer surgery who want to reduce their anxiety. Participants will listen to guided meditation recordings to see if it helps calm their nerves before the operation.
Recruiting
TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
N/A Orange, California +4 sites NCT07048574
This trial is looking for children aged 18 months to 11 years who have cystic fibrosis. Participation involves being followed by a care team and discussing mental health issues like depression and anxiety.
Recruiting
AROMA-NT: Essential Oils and Wearable TENS Device for Chronic Nausea
NA Columbus, Ohio NCT07720336
This trial is looking for adults with chronic nausea and anxiety. Participants will use essential oils and a wearable device to see how these treatments affect their symptoms over several months.
Recruiting
A Precision Medicine Approach to Target Engagement for Emotion Regulation
NA Columbus, Ohio NCT05651295
This trial is looking for people who have trouble managing their emotions. Participants will learn different skills to help reduce their negative feelings and determine which skills work best for them.
Recruiting
Virtual Patient Groups for Sarcoidosis Associated Fatigue
NA Cleveland, Ohio NCT07073963
This trial is looking for adults with sarcoidosis who experience fatigue. Participants will either join an 8-week mindfulness program online or a monthly support group, and will complete surveys about their fatigue, anxiety, and depression.
Recruiting

Where the Anxiety studies are in Ohio

  • The Ohio State University, Columbus3 trials
  • Ohio State University Comprehensive Cancer Center, Columbus2 trials
  • Ohio State University Wexner Medical Center, Columbus2 trials
  • Case Western Reserve University, Cleveland1 trial
  • Children's Hospital Medical Center, Cincinnati, Cincinnati1 trial
  • Cincinnati Children's Hospital Medical Center, Cincinnati1 trial

Counts are recruiting studies listing at least one site in Ohio, from ClinicalTrials.gov, refreshed every two days.

Anxiety clinical trials in Ohio: common questions

How many Anxiety clinical trials are recruiting in Ohio?
TrialFinder currently lists 24 recruiting Anxiety clinical trials with study sites in Ohio. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Anxiety clinical trials located in Ohio?
Study sites for the Anxiety trials listed on this page include Cincinnati, Columbus, Cleveland, Athens. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Anxiety clinical trial in Ohio?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Anxiety trials in Ohio also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Anxiety clinical trial in Ohio?
Each study sets its own criteria based on age, Anxiety diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I take part in an anxiety trial if I am already in therapy?
Often yes for medicine trials, if the therapy is ongoing and stable. Trials testing a therapy usually ask that you are not starting another one at the same time. The listing states its rule.
Are there anxiety studies I can do online?
Yes. Many app-based and video-therapy studies are mostly remote, though most still need one or two in-person visits, so distance to the site still matters.
Is there a placebo in anxiety trials?
Medicine trials usually include a placebo arm and say so in the consent form. Therapy trials compare against usual care or a group that receives the program after a delay.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Anxiety trials near you in Ohio.

Get Matched — Free
No insurance required

Anxiety disorder trials study CBT approaches, novel anxiolytics, MDMA-assisted therapy, and neuromodulation techniques for GAD, social anxiety, and PTSD.

All Anxiety trials →