50 Recruiting Trials

Clinical Trials
for Stroke in Ohio

50 clinical trials for Stroke are currently recruiting participants at study sites in Ohio. Study-related care is provided at no cost.

50
Recruiting trials
40
Study sites
9
Cities
11
Industry-sponsored
5
Phase 2
12
Phase 3

Stroke clinical trials in Ohio: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Ohio, recruiting stroke studies are concentrated in Cleveland, Cincinnati, Columbus and Toledo, with sites in 5 other cities. 11 of the 50 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 20 of 50 recruiting Stroke trials in Ohio

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
PHASE2 Fairhope, Alabama +4 sites NCT05065216
This trial is looking for adults who have had a moderate stroke and present within 24 hours of the onset. Participants will receive a study medication to see if it helps improve their condition.
Recruiting
Telerehabilitation In The Home After Stroke
NA Downey, California +4 sites NCT06682429
This trial is looking for people who have arm weakness from a stroke that happened 90 to 150 days ago. Participants will receive telerehabilitation to improve their arm function, alongside usual care, for 6 weeks.
Recruiting
I-Score: Intensive Stroke Cycling for Optimal Recovery and Economic Value
NA Cleveland, Ohio NCT06585943
This trial is looking for people who have had a stroke 3 to 9 months ago and want to improve their movement. Participants will engage in a special exercise program to help recovery in their arms and legs.
Recruiting
Self-Supervised Constraint-Induced Movement Therapy for Stroke Recovery
NA Columbus, Ohio NCT07723300
This trial is looking for adults with arm and hand weakness after a stroke. Participants will follow a therapy program for two weeks to help improve their arm and hand use while filling out surveys before and after the program.
Recruiting
Pilot/Pivotal Study of DBS+Rehab After Stroke
NA Phoenix, Arizona +4 sites NCT05701280
This trial is looking for people who had a stroke and still have weakness in their arm. Participants will receive treatment to help improve their arm function.
Recruiting
HIT-Stroke Trial 2
NA Cincinnati, Ohio +2 sites NCT06268041
This trial is looking for people who had a stroke at least 6 months ago and still have trouble walking. Participants will do walking exercises with a physical therapist for 12 weeks, three times a week.
Recruiting
Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation
NA Cleveland, Ohio NCT03857529
This trial is looking for stroke patients with weakened arm function. Participants will receive brain stimulation and electrical stimulation to help improve hand control.
Recruiting
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
NA Cleveland, Ohio NCT05866003
This trial is looking for adults who have lost some hand movement after a stroke. Participants will receive brain stimulation along with therapy to improve their ability to move their hands.
Recruiting
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
N/A Birmingham, Alabama +4 sites NCT05911568
This trial is looking for adults who had a stroke and have moderate to severe disability before it. Participants will compare two treatment options: a procedure to remove blood clots or regular medical care without the procedure.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Genetic and Environmental Risk Factors for Hemorrhagic Stroke
N/A Chicago, Illinois +4 sites NCT00682695
This trial is looking for adults who have had a hemorrhagic stroke. Participants will provide consent for interviews, blood pressure checks, and blood sampling.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
PHASE3 Mobile, Alabama +4 sites NCT05611242
This trial is looking for adults aged 18 to 79 who have had an acute ischemic stroke. Participants will receive a specific treatment for blocked arteries in the brain to see if it's more effective than other approaches.
Recruiting
Optimizing Reperfusion to Improve Outcomes and Neurologic Function
PHASE2 Long Beach, California +4 sites NCT06990867
This trial is looking for adults with acute ischemic stroke who seek care within 4.5 to 24 hours. Participants will receive either a new treatment called JX10 or a placebo to see how it affects recovery and safety.
Recruiting
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
PHASE3 Tucson, Arizona +4 sites NCT05691244
This trial is looking for adults who have had an acute ischemic stroke. Participants will receive a new treatment called sovateltide along with standard care and will be monitored for safety and effectiveness.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)
PHASE2 Scottsdale, Arizona +4 sites NCT06226805
This trial is looking for adults who have had an acute ischemic stroke within the last 24 hours. Participants will receive either the study drug or a placebo and will be monitored for 90 days.
Recruiting
Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
NA New Haven, Connecticut +4 sites NCT06094478
This trial is looking for adult patients who have experienced a stroke. It aims to find better ways for hospitals to quickly assess and transfer patients needing advanced treatment for their stroke.
Recruiting
Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation
NA Cleveland, Ohio +3 sites NCT05983185
This trial is looking for veterans who have had a right brain stroke and have difficulties with daily activities. Participants will undergo special training with prisms to help improve their ability to function.
Recruiting
Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe
NA Toledo, Ohio +3 sites NCT05983757
This trial is looking for adults who have had a specific type of stroke and are eligible for a certain treatment. Participants will receive a procedure to remove a blood clot instead of standard medical care.
Recruiting

Where the Stroke studies are in Ohio

  • University of Cincinnati Medical Center, Cincinnati9 trials
  • Cleveland Clinic, Cleveland7 trials
  • University of Cincinnati, Cincinnati7 trials
  • OSU Wexner Medical Center, Columbus6 trials
  • ProMedica Toledo Hospital, Toledo5 trials
  • Ohio State University, Columbus4 trials

Counts are recruiting studies listing at least one site in Ohio, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Ohio: common questions

How many Stroke clinical trials are recruiting in Ohio?
TrialFinder currently lists 50 recruiting Stroke clinical trials with study sites in Ohio. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Ohio?
Study sites for the Stroke trials listed on this page include Cleveland, Columbus, Cincinnati, Toledo. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Ohio?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Ohio also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Ohio?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
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Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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