Stroke Trials / Trials in Maryland
40 Recruiting Trials

Clinical Trials
for Stroke in Maryland

40 clinical trials for Stroke are currently recruiting participants at study sites in Maryland. Study-related care is provided at no cost.

40
Recruiting trials
26
Study sites
5
Cities
5
Industry-sponsored
6
Phase 2
3
Phase 3

Stroke clinical trials in Maryland: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Maryland, recruiting stroke studies are concentrated in Baltimore, Bethesda, College Park and Frederick, with sites in 1 other city. 5 of the 40 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 20 of 40 recruiting Stroke trials in Maryland

Myofascial Dysfunction in Post Stroke Shoulder Pain
PHASE2 Baltimore, Maryland NCT06718413
This trial is looking for people who have shoulder pain after having a stroke. Participants will be asked to meet certain criteria and take part in assessments to understand the pain better.
Recruiting
Facilitating Neuroplastic Changes of Acute Stroke Survivors
PHASE1 Baltimore, Maryland +2 sites NCT06404268
This trial is looking for people who have had a stroke and have weakness on one side of the body. Participants will use a special robot to help with rehabilitation while in bed during the early recovery stage after a stroke.
Recruiting
Hybrid Robot+FES Stroke Rehabilitation
PHASE1 Baltimore, Maryland NCT04550728
This trial is looking for people who have had a stroke and need help with movement. Participants will use a special robotic device, sometimes combined with electrical stimulation, to aid in their recovery at home.
Recruiting
Robot Aided Rehabilitation - Intervention
NA Baltimore, Maryland NCT02359253
This trial is looking for people who have had a stroke and want to improve their arm and hand movement. Participants will receive specific treatments and training to help with their recovery.
Recruiting
TDCS to Improve Post-Stroke Cognitive Impairment
NA Baltimore, Maryland NCT05195398
This trial is looking for adults who have had a mild stroke and are experiencing cognitive impairment. Participants will receive brain stimulation treatment along with cognitive exercises or a placebo with the same exercises, and their progress will be monitored over time.
Recruiting
Pilot/Pivotal Study of DBS+Rehab After Stroke
NA Baltimore, Maryland +4 sites NCT05701280
This trial is looking for people who had a stroke and still have weakness in their arm. Participants will receive treatment to help improve their arm function.
Recruiting
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
N/A Bethesda, Maryland NCT06615973
This trial is looking for adults who have had a stroke to learn how social factors affect mental health after their stroke. Participants will have a 45-minute phone call to discuss their health and answer questions about their background.
Recruiting
Robot Aided Rehabilitation - Multi-joint Evaluations
N/A Baltimore, Maryland NCT02359812
This trial is looking for people who have had a stroke within the last month. Participants will take part in assessments to measure their arm and hand recovery using a robot.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Genetic and Environmental Risk Factors for Hemorrhagic Stroke
N/A Baltimore, Maryland +4 sites NCT00682695
This trial is looking for adults who have had a hemorrhagic stroke. Participants will provide consent for interviews, blood pressure checks, and blood sampling.
Recruiting
Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
N/A Baltimore, Maryland NCT04188522
This trial is looking for adults who have recently had a minor stroke. Participants will undergo brain scans at the University of Maryland to help researchers understand cognitive recovery.
Recruiting
Optimizing Reperfusion to Improve Outcomes and Neurologic Function
PHASE2 Long Beach, California +4 sites NCT06990867
This trial is looking for adults with acute ischemic stroke who seek care within 4.5 to 24 hours. Participants will receive either a new treatment called JX10 or a placebo to see how it affects recovery and safety.
Recruiting
Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke
PHASE2 Baltimore, Maryland +2 sites NCT06440707
This trial is looking for people who have had an acute ischemic stroke and are not eligible for standard treatments. Participants will receive a new type of treatment involving a weak electrical current aimed at improving blood flow to the brain.
Recruiting
Sensory-Motor Rehabilitation Post Stroke
NA Baltimore, Maryland NCT02369770
This trial is looking for people who have had a stroke and have difficulty with movement and sensation. Participants will use a wearable robot to help with recovery and improve movement skills.
Recruiting
Scrambler Therapy for Post-Stroke Pain
NA Baltimore, Maryland NCT05563038
This trial is looking for people who have had a stroke and are experiencing pain as a result. Participants will receive a treatment called Scrambler Therapy to see how it compares to traditional pain medications.
Recruiting
Continuous Dual Aspiration Technique With Zoom System for Stroke
N/A Huntsville, Alabama +4 sites NCT07491952
This trial is looking for adults who have had an ischemic stroke. Participants will undergo a specific type of thrombectomy procedure using a new technique.
Recruiting
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
N/A Phoenix, Arizona +4 sites NCT04916210
This trial is looking for adults who have had a stroke and want to help researchers learn more about how strokes affect thinking and memory. Participants will undergo evaluations to understand their recovery and brain health after a stroke.
Recruiting
Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline
N/A Baltimore, Maryland NCT05556395
This trial is looking for people who have had an ischemic stroke. Participants will help researchers learn how the condition affects thinking and memory over the next three years.
Recruiting
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
PHASE1 Baltimore, Maryland NCT07053917
This trial is looking for adults who have had a stroke at least a year ago and want to explore a new treatment with psilocybin. Participants will need to follow specific rules during the study and will be monitored closely.
Recruiting
Self-Administered Gaming and Exercise at Home (SAGEH)
NA Baltimore, Maryland NCT05929027
This trial is looking for adults who have had a stroke within the last 6 weeks and have difficulty using their arm or hand. Participants will compare regular therapy with additional self-directed exercises at home to improve hand function.
Recruiting
See all 40 Stroke trials in Maryland

Where the Stroke studies are in Maryland

Research sites running the most studies
  • Johns Hopkins School of Medicine, Baltimore4 trials
  • National Institutes of Health Clinical Center, Bethesda4 trials
  • Johns Hopkins Bayview Medical Center, Baltimore3 trials
  • Johns Hopkins Hospital, Baltimore3 trials
  • Johns Hopkins Medicine, Baltimore3 trials
  • University of Maryland, Baltimore3 trials
By city

Counts are recruiting studies listing at least one site in Maryland, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Maryland: common questions

How many Stroke clinical trials are recruiting in Maryland?
TrialFinder currently lists 40 recruiting Stroke clinical trials with study sites in Maryland. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Maryland?
Study sites for the Stroke trials listed on this page include Baltimore, Bethesda. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Maryland?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Maryland also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Maryland?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
Stroke Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Stroke Trials

Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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