COPD Trials / Trials in Maryland
15 Recruiting Trials

Clinical Trials
for COPD in Maryland

15 clinical trials for COPD are currently recruiting participants at study sites in Maryland. Study-related care is provided at no cost.

15
Recruiting trials
18
Study sites
9
Cities
9
Industry-sponsored
3
Phase 2
8
Phase 3

COPD clinical trials in Maryland: what to expect

COPD trials test new inhaler combinations, biologic injections for people whose flare-ups continue despite inhalers, and treatments for the cough and mucus that come with chronic bronchitis. Others study pulmonary rehabilitation and exercise, valves and other procedures for emphysema, home oxygen and remote monitoring, and programs to stop smoking. Most enroll people with moderate to severe disease who still have symptoms on their current treatment.

In Maryland, recruiting copd studies are concentrated in Baltimore, Potomac, Salisbury and Columbia, with sites in 5 other cities. 9 of the 15 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who COPD trials usually look for

Trials confirm COPD with a breathing test at screening and set a range for lung function, usually between 30 and 80 percent of predicted. Most ask for a smoking history of at least ten pack-years, though current smokers are generally accepted. Biologic trials require one or two flare-ups in the past year needing steroids or antibiotics and sometimes a blood eosinophil count above a threshold. Common exclusions are asthma as the main diagnosis, another significant lung disease and a flare-up in the past four weeks. Ages are usually 40 to 80.

What taking part involves

Screening includes spirometry, blood work and a symptom questionnaire, then a short run-in while you record symptoms. Drug trials run six to twelve months with visits every four to twelve weeks, breathing tests, a six-minute walk in some, and a diary or app. Your maintenance inhalers continue, sometimes replaced by study-supplied versions, and rescue inhaler is always allowed. Rehabilitation trials involve two or three sessions a week for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your inhalers stay the same; how breathing tests and walking tests are scheduled; the chance of placebo; what to do during a flare-up while enrolled; and whether oxygen users are accepted.

Showing 15 of 15 recruiting COPD trials in Maryland

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
NA Birmingham, Alabama +4 sites NCT05204888
This trial is looking for people with moderate to very severe COPD who have had a recent severe worsening of their condition. Participants will use the myAirvo 3 device at home while receiving their usual COPD care for at least one year.
Recruiting
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
PHASE3 Birmingham, Alabama +4 sites NCT06878261
This trial is looking for adults aged 40 to 80 who have had COPD for at least a year. Participants will take the study drug Tezepelumab and be monitored for its effects on their condition.
Recruiting
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
PHASE3 Foley, Alabama +4 sites NCT06883305
This trial is looking for adults with moderate to very severe COPD. Participants will be required to take part in assessments and treatments involving Tezepelumab.
Recruiting
Multi-Center Clean Air Randomized Controlled Trial in COPD
PHASE3 Baltimore, Maryland +4 sites NCT06376994
This trial is looking for people with chronic obstructive pulmonary disease (COPD) to see if using an air cleaner can help them. Participants will be asked questions about their health and will have an air cleaner placed in their home to test its effectiveness.
Recruiting
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
PHASE2 Birmingham, Alabama +4 sites NCT07059091
This trial is looking for individuals with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Participants will take a medication called omalizumab for about a year and have follow-up calls afterwards.
Recruiting
OMEGA - Dietary Intervention - COPD Trial
NA Baltimore, Maryland NCT05297279
This trial is looking for people over 40 with Chronic Obstructive Pulmonary Disease (COPD) to try a dietary program that increases omega-3 intake. Participants will receive food deliveries and dietary recommendations to see if this helps improve their lung health.
Recruiting
SPIROMICS Study of Early COPD Progression (SOURCE)
N/A Birmingham, Alabama +4 sites NCT05033990
This trial is looking for people aged 30-55 to study early chronic obstructive pulmonary disease (COPD). Participants will undergo tests like breathing tests and provide samples to help researchers understand who is at risk of developing COPD.
Recruiting
Effectiveness of the WearME System for COPD Severity and Respiratory Function
N/A Baltimore, Maryland +1 sites NCT06751537
This trial is looking for adults with Chronic Obstructive Pulmonary Disease (COPD) to see how well the WearME system can monitor their condition. Participants will have tests done while using the WearME device to compare its results with standard methods.
Recruiting
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
PHASE3 Athens, Alabama +4 sites NCT06283966
This trial is looking for adults aged 40 to 80 with Chronic Obstructive Pulmonary Disease (COPD). Participants will receive a combination inhaler treatment and attend study visits for assessments.
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
PHASE2 Birmingham, Alabama +4 sites NCT07082738
This trial is looking for people with moderate to very severe COPD to test the effects of a new drug called AZD6793. Participants will take AZD6793 or a placebo and help researchers learn about its safety and effectiveness.
Recruiting
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
PHASE3 Bakersfield, California +4 sites NCT06959095
This trial is looking for adults aged 40 to 80 with moderate to severe COPD and type 2 inflammation. Participants will take a new medicine called depemokimab to see how it helps manage their condition.
Recruiting
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
PHASE3 Sheffield, Alabama +4 sites NCT06961214
This trial is looking for adults with moderate to severe COPD and type 2 inflammation. Participants will be taking depemokimab as an additional treatment along with their current medications.
Recruiting
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
PHASE3 Birmingham, Alabama +4 sites NCT07190222
This trial is looking for adults aged 40 to 80 with chronic obstructive pulmonary disease (COPD) that is not well controlled. Participants will receive either lunsekimig or a placebo for about 48 weeks, followed by an 8-week follow-up.
Recruiting
Trial to Determine Effective Aspirin Dose in COPD
PHASE3 Baltimore, Maryland NCT05265299
This trial is looking for former smokers aged 40 and older who have been diagnosed with chronic obstructive pulmonary disease (COPD). Participants will take aspirin to see if it helps improve breathing symptoms and reduce flare-ups.
Recruiting
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
PHASE2 Mobile, Alabama +4 sites NCT07610395
This trial is looking for people with COPD who have had recent respiratory infections. Participants will take a medication called vapendavir to see if it helps reduce their cold symptoms.
Recruiting
See all 15 COPD trials in Maryland

Where the COPD studies are in Maryland

Research sites running the most studies
  • Research Site, Baltimore3 trials
  • Johns Hopkins, Baltimore2 trials
  • Johns Hopkins Bayview Medical Center, Baltimore2 trials
  • Research Site, Potomac2 trials
  • GSK Investigational Site, Baltimore1 trial
  • GSK Investigational Site, Rockville1 trial
By city

Counts are recruiting studies listing at least one site in Maryland, from ClinicalTrials.gov, refreshed every two days.

COPD clinical trials in Maryland: common questions

How many COPD clinical trials are recruiting in Maryland?
TrialFinder currently lists 15 recruiting COPD clinical trials with study sites in Maryland. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are COPD clinical trials located in Maryland?
Study sites for the COPD trials listed on this page include Baltimore. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a COPD clinical trial in Maryland?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many COPD trials in Maryland also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a COPD clinical trial in Maryland?
Each study sets its own criteria based on age, COPD diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to quit smoking to join a COPD trial?
Most COPD trials accept current smokers; some require that you have stopped, and smoking-cessation trials are specifically for people who still smoke. The listing states the rule.
What tests confirm COPD for a trial?
Spirometry, a breathing test done at the site before and after a bronchodilator, which gives the lung function figure trials use to set their range. You do not need recent results to ask.
Will I keep using my inhalers during a trial?
Yes. Trials add the study treatment to your maintenance inhalers or supply a standardized equivalent, and a rescue inhaler is always permitted.
COPD Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About COPD Trials

COPD trials investigate bronchodilators, anti-inflammatory biologics, pulmonary rehabilitation, and lung-volume reduction procedures for chronic obstructive lung disease.

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