COPD Trials / Trials in Virginia
11 Recruiting Trials

Clinical Trials
for COPD in Virginia

11 clinical trials for COPD are currently recruiting participants at study sites in Virginia. Study-related care is provided at no cost.

11
Recruiting trials
13
Study sites
10
Cities
9
Industry-sponsored
2
Phase 2
3
Phase 3

COPD clinical trials in Virginia: what to expect

COPD trials test new inhaler combinations, biologic injections for people whose flare-ups continue despite inhalers, and treatments for the cough and mucus that come with chronic bronchitis. Others study pulmonary rehabilitation and exercise, valves and other procedures for emphysema, home oxygen and remote monitoring, and programs to stop smoking. Most enroll people with moderate to severe disease who still have symptoms on their current treatment.

In Virginia, recruiting copd studies are concentrated in Falls Church, Williamsburg, Norfolk and Richmond, with sites in 6 other cities. 9 of the 11 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who COPD trials usually look for

Trials confirm COPD with a breathing test at screening and set a range for lung function, usually between 30 and 80 percent of predicted. Most ask for a smoking history of at least ten pack-years, though current smokers are generally accepted. Biologic trials require one or two flare-ups in the past year needing steroids or antibiotics and sometimes a blood eosinophil count above a threshold. Common exclusions are asthma as the main diagnosis, another significant lung disease and a flare-up in the past four weeks. Ages are usually 40 to 80.

What taking part involves

Screening includes spirometry, blood work and a symptom questionnaire, then a short run-in while you record symptoms. Drug trials run six to twelve months with visits every four to twelve weeks, breathing tests, a six-minute walk in some, and a diary or app. Your maintenance inhalers continue, sometimes replaced by study-supplied versions, and rescue inhaler is always allowed. Rehabilitation trials involve two or three sessions a week for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your inhalers stay the same; how breathing tests and walking tests are scheduled; the chance of placebo; what to do during a flare-up while enrolled; and whether oxygen users are accepted.

Showing 11 of 11 recruiting COPD trials in Virginia

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
NA Birmingham, Alabama +4 sites NCT07051707
This trial is looking for adults with chronic obstructive pulmonary disease (COPD) who have been receiving standard medical care. Participants will undergo a one-time procedure to help improve their breathing.
Recruiting
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
NA Salem, Virginia NCT05254431
This trial is looking for veterans who have both chronic obstructive pulmonary disease and obstructive sleep apnea. Participants will help develop an exercise plan aimed at improving their health and reducing risks associated with these conditions.
Recruiting
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
PHASE3 Birmingham, Alabama +4 sites NCT06878261
This trial is looking for adults aged 40 to 80 who have had COPD for at least a year. Participants will take the study drug Tezepelumab and be monitored for its effects on their condition.
Recruiting
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
PHASE2 Phoenix, Arizona +4 sites NCT07684820
This trial is looking for people with chronic obstructive pulmonary disease (COPD) who have had recent flare-ups of their condition. Participants will take either the study drug or a placebo every day for a year.
Recruiting
COPD Exacerbation Follow Up
N/A Falls Church, Virginia +4 sites NCT07118306
This trial is looking for people who are 40 or older and have COPD. Participants will help evaluate an AI tool designed to improve follow-up care after a severe worsening of their condition.
Recruiting
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
NA Birmingham, Alabama +4 sites NCT06891755
This trial is looking for adults with COPD and emphysema who experience difficulty breathing. Participants will receive a device to help open their airways and will be followed for three years.
Recruiting
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
PHASE3 Athens, Alabama +4 sites NCT06283966
This trial is looking for adults aged 40 to 80 with Chronic Obstructive Pulmonary Disease (COPD). Participants will receive a combination inhaler treatment and attend study visits for assessments.
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
PHASE2 Birmingham, Alabama +4 sites NCT07082738
This trial is looking for people with moderate to very severe COPD to test the effects of a new drug called AZD6793. Participants will take AZD6793 or a placebo and help researchers learn about its safety and effectiveness.
Recruiting
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
PHASE3 Chandler, Arizona +4 sites NCT07190209
This trial is looking for adults aged 40 to 80 with chronic obstructive pulmonary disease (COPD) that isn't well controlled. Participants will receive either lunsekimig or a placebo for approximately 48 weeks, followed by an 8-week follow-up.
Recruiting
The ROAM Research Study Therapy (LTOT) Version
N/A Charlottesville, Virginia NCT06810323
This trial is looking for people with chronic lung disease who use oxygen therapy at home. Participants will help test a device that tracks how they use oxygen over time without needing an internet connection.
Recruiting
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
NA Phoenix, Arizona +4 sites NCT06035120
This trial is looking for people aged 40 to 80 with severe emphysema who have certain breathing issues. Participants will receive a treatment called AeriSeal Foam and may have a valve placed to help improve lung function, with follow-up for two years.
Recruiting
See all 11 COPD trials in Virginia

Where the COPD studies are in Virginia

Research sites running the most studies
  • Inova Fairfax Hospital, Falls Church2 trials
  • Research Site, Williamsburg2 trials
  • Research Site, Norfolk2 trials
  • Burke Internal Medicine, Inc., Burke1 trial
  • Inova Health Care Services, Falls Church1 trial
  • Research Site, Newport News1 trial
By city

Counts are recruiting studies listing at least one site in Virginia, from ClinicalTrials.gov, refreshed every two days.

COPD clinical trials in Virginia: common questions

How many COPD clinical trials are recruiting in Virginia?
TrialFinder currently lists 11 recruiting COPD clinical trials with study sites in Virginia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are COPD clinical trials located in Virginia?
Study sites for the COPD trials listed on this page include Salem, Falls Church, Charlottesville. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a COPD clinical trial in Virginia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many COPD trials in Virginia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a COPD clinical trial in Virginia?
Each study sets its own criteria based on age, COPD diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to quit smoking to join a COPD trial?
Most COPD trials accept current smokers; some require that you have stopped, and smoking-cessation trials are specifically for people who still smoke. The listing states the rule.
What tests confirm COPD for a trial?
Spirometry, a breathing test done at the site before and after a bronchodilator, which gives the lung function figure trials use to set their range. You do not need recent results to ask.
Will I keep using my inhalers during a trial?
Yes. Trials add the study treatment to your maintenance inhalers or supply a standardized equivalent, and a rescue inhaler is always permitted.
COPD Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About COPD Trials

COPD trials investigate bronchodilators, anti-inflammatory biologics, pulmonary rehabilitation, and lung-volume reduction procedures for chronic obstructive lung disease.

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