24 Recruiting Trials
Clinical Trials
for COPD in Michigan
24 clinical trials for COPD are currently recruiting participants at study sites in Michigan. Study-related care is provided at no cost.
24
Recruiting trials
30
Study sites
13
Cities
16
Industry-sponsored
6
Phase 2
10
Phase 3
COPD clinical trials in Michigan: what to expect
COPD trials test new inhaler combinations, biologic injections for people whose flare-ups continue despite inhalers, and treatments for the cough and mucus that come with chronic bronchitis. Others study pulmonary rehabilitation and exercise, valves and other procedures for emphysema, home oxygen and remote monitoring, and programs to stop smoking. Most enroll people with moderate to severe disease who still have symptoms on their current treatment.
In Michigan, recruiting copd studies are concentrated in Ann Arbor, Detroit, Allen Park and Dearborn, with sites in 9 other cities. 16 of the 24 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who COPD trials usually look for
Trials confirm COPD with a breathing test at screening and set a range for lung function, usually between 30 and 80 percent of predicted. Most ask for a smoking history of at least ten pack-years, though current smokers are generally accepted. Biologic trials require one or two flare-ups in the past year needing steroids or antibiotics and sometimes a blood eosinophil count above a threshold. Common exclusions are asthma as the main diagnosis, another significant lung disease and a flare-up in the past four weeks. Ages are usually 40 to 80.
What taking part involves
Screening includes spirometry, blood work and a symptom questionnaire, then a short run-in while you record symptoms. Drug trials run six to twelve months with visits every four to twelve weeks, breathing tests, a six-minute walk in some, and a diary or app. Your maintenance inhalers continue, sometimes replaced by study-supplied versions, and rescue inhaler is always allowed. Rehabilitation trials involve two or three sessions a week for eight to twelve weeks. Study care is free and visits are usually paid.
Questions worth asking the study team
Whether your inhalers stay the same; how breathing tests and walking tests are scheduled; the chance of placebo; what to do during a flare-up while enrolled; and whether oxygen users are accepted.
Showing 20 of 24 recruiting COPD trials in Michigan
Effect of Ensifentrine on Sputum Markers of Inflammation in COPD
Recruiting
This trial is looking for people with COPD who smoke or have a history of smoking. Participants will take either ensifentrine or a placebo for two 8-week periods and attend several clinic visits over 24 weeks.
Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
Recruiting
This trial is looking for adults with chronic obstructive pulmonary disease (COPD) who have been receiving standard medical care. Participants will undergo a one-time procedure to help improve their breathing.
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Recruiting
This trial is looking for people with moderate to very severe COPD who have had a recent severe worsening of their condition. Participants will use the myAirvo 3 device at home while receiving their usual COPD care for at least one year.
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Recruiting
This trial is looking for adults aged 40 to 80 who have had COPD for at least a year. Participants will take the study drug Tezepelumab and be monitored for its effects on their condition.
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Recruiting
This trial is looking for adults with moderate to very severe COPD. Participants will be required to take part in assessments and treatments involving Tezepelumab.
Multi-Center Clean Air Randomized Controlled Trial in COPD
Recruiting
This trial is looking for people with chronic obstructive pulmonary disease (COPD) to see if using an air cleaner can help them. Participants will be asked questions about their health and will have an air cleaner placed in their home to test its effectiveness.
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
Recruiting
This trial is looking for individuals with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Participants will take a medication called omalizumab for about a year and have follow-up calls afterwards.
SPIROMICS Study of Early COPD Progression (SOURCE)
Recruiting
This trial is looking for people aged 30-55 to study early chronic obstructive pulmonary disease (COPD). Participants will undergo tests like breathing tests and provide samples to help researchers understand who is at risk of developing COPD.
University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2
Recruiting
This trial is looking for current or former smokers aged 50 to 80 who may have COPD. Participants will undergo lung cancer screening CT scans that help identify COPD status via additional tests.
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Recruiting
This trial is looking for adults with COPD and emphysema who experience difficulty breathing. Participants will receive a device to help open their airways and will be followed for three years.
Supporting Evidence-based Responses to Emotional Needs in Emphysema
Recruiting
This trial is looking for adults with COPD who want to improve their emotional well-being. Participants will take part in either a training program to help cope with stress or an education program about COPD over 12 weeks.
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Recruiting
This trial is looking for adults aged 40 to 80 with Chronic Obstructive Pulmonary Disease (COPD). Participants will receive a combination inhaler treatment and attend study visits for assessments.
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Recruiting
This trial is looking for people with moderate to very severe COPD to test the effects of a new drug called AZD6793. Participants will take AZD6793 or a placebo and help researchers learn about its safety and effectiveness.
Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
Recruiting
This trial is looking for older veterans with sleep apnea and chronic obstructive pulmonary disease (COPD). Participants will be studied to see how their conditions affect thinking and memory and whether treatment can improve these issues.
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Recruiting
This trial is looking for adults aged 35 to 80 with moderate to severe COPD. Participants will receive either the study medicine PF-07275315 or a placebo through shots over 24 to 68 weeks and will attend multiple clinic visits during this time.
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Recruiting
This trial is looking for adults aged 40 to 80 with chronic obstructive pulmonary disease (COPD) that isn't well controlled. Participants will receive either lunsekimig or a placebo for approximately 48 weeks, followed by an 8-week follow-up.
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Recruiting
This trial is looking for adults aged 40 to 80 with moderate to severe COPD and type 2 inflammation. Participants will take a new medicine called depemokimab to see how it helps manage their condition.
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Recruiting
This trial is looking for adults with moderate to severe COPD and type 2 inflammation. Participants will be taking depemokimab as an additional treatment along with their current medications.
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Recruiting
This trial is looking for adults aged 40 to 80 with chronic obstructive pulmonary disease (COPD) that is not well controlled. Participants will receive either lunsekimig or a placebo for about 48 weeks, followed by an 8-week follow-up.
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Recruiting
This trial is looking for adults with moderate to severe COPD who have certain inflammation in their lungs, and who are at risk for worsening symptoms. They need to have been diagnosed for at least a year and must not have had any serious lung issues in the past month. It's important that they don't have asthma or other significant lung diseases and aren’t currently using supplemental oxygen.
Where the COPD studies are in Michigan
Research sites running the most studies
- University of Michigan, Ann Arbor6 trials
- GSK Investigational Site, Clarkston2 trials
- GSK Investigational Site, Allen Park2 trials
- Henry Ford Health, Detroit2 trials
- John D. Dingell VA Medical Center, Detroit, MI, Detroit2 trials
- Oakland Medical Research, Troy2 trials
By city
Counts are recruiting studies listing at least one site in Michigan, from ClinicalTrials.gov, refreshed every two days.
COPD clinical trials in Michigan: common questions
How many COPD clinical trials are recruiting in Michigan?
TrialFinder currently lists 24 recruiting COPD clinical trials with study sites in Michigan. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are COPD clinical trials located in Michigan?
Study sites for the COPD trials listed on this page include Ann Arbor, Detroit. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a COPD clinical trial in Michigan?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many COPD trials in Michigan also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a COPD clinical trial in Michigan?
Each study sets its own criteria based on age, COPD diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to quit smoking to join a COPD trial?
Most COPD trials accept current smokers; some require that you have stopped, and smoking-cessation trials are specifically for people who still smoke. The listing states the rule.
What tests confirm COPD for a trial?
Spirometry, a breathing test done at the site before and after a bronchodilator, which gives the lung function figure trials use to set their range. You do not need recent results to ask.
Will I keep using my inhalers during a trial?
Yes. Trials add the study treatment to your maintenance inhalers or supply a standardized equivalent, and a rescue inhaler is always permitted.
COPD Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About COPD Trials
COPD trials investigate bronchodilators, anti-inflammatory biologics, pulmonary rehabilitation, and lung-volume reduction procedures for chronic obstructive lung disease.
All COPD trials →