7 Recruiting Trials

Clinical Trials
for COPD in Iowa

7 clinical trials for COPD are currently recruiting participants at study sites in Iowa. Study-related care is provided at no cost.

7
Recruiting trials
5
Study sites
4
Cities
3
Industry-sponsored
2
Phase 2
2
Phase 3

COPD clinical trials in Iowa: what to expect

COPD trials test new inhaler combinations, biologic injections for people whose flare-ups continue despite inhalers, and treatments for the cough and mucus that come with chronic bronchitis. Others study pulmonary rehabilitation and exercise, valves and other procedures for emphysema, home oxygen and remote monitoring, and programs to stop smoking. Most enroll people with moderate to severe disease who still have symptoms on their current treatment.

In Iowa, recruiting copd studies are concentrated in Iowa City, West Des Moines, Des Moines and Sioux City. 3 of the 7 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who COPD trials usually look for

Trials confirm COPD with a breathing test at screening and set a range for lung function, usually between 30 and 80 percent of predicted. Most ask for a smoking history of at least ten pack-years, though current smokers are generally accepted. Biologic trials require one or two flare-ups in the past year needing steroids or antibiotics and sometimes a blood eosinophil count above a threshold. Common exclusions are asthma as the main diagnosis, another significant lung disease and a flare-up in the past four weeks. Ages are usually 40 to 80.

What taking part involves

Screening includes spirometry, blood work and a symptom questionnaire, then a short run-in while you record symptoms. Drug trials run six to twelve months with visits every four to twelve weeks, breathing tests, a six-minute walk in some, and a diary or app. Your maintenance inhalers continue, sometimes replaced by study-supplied versions, and rescue inhaler is always allowed. Rehabilitation trials involve two or three sessions a week for eight to twelve weeks. Study care is free and visits are usually paid.

Questions worth asking the study team

Whether your inhalers stay the same; how breathing tests and walking tests are scheduled; the chance of placebo; what to do during a flare-up while enrolled; and whether oxygen users are accepted.

Showing 7 of 7 recruiting COPD trials in Iowa

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital
NA Des Moines, Iowa +3 sites NCT07222410
This trial is looking for people with COPD who are in the hospital and need extra oxygen. Participants will use the Airvo 3 device to help keep their oxygen levels stable.
Recruiting
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
NA Birmingham, Alabama +4 sites NCT05204888
This trial is looking for people with moderate to very severe COPD who have had a recent severe worsening of their condition. Participants will use the myAirvo 3 device at home while receiving their usual COPD care for at least one year.
Recruiting
Multi-Center Clean Air Randomized Controlled Trial in COPD
PHASE3 Iowa City, Iowa +4 sites NCT06376994
This trial is looking for people with chronic obstructive pulmonary disease (COPD) to see if using an air cleaner can help them. Participants will be asked questions about their health and will have an air cleaner placed in their home to test its effectiveness.
Recruiting
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
PHASE2 Birmingham, Alabama +4 sites NCT07059091
This trial is looking for individuals with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Participants will take a medication called omalizumab for about a year and have follow-up calls afterwards.
Recruiting
SPIROMICS Study of Early COPD Progression (SOURCE)
N/A Birmingham, Alabama +4 sites NCT05033990
This trial is looking for people aged 30-55 to study early chronic obstructive pulmonary disease (COPD). Participants will undergo tests like breathing tests and provide samples to help researchers understand who is at risk of developing COPD.
Recruiting
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
PHASE3 Athens, Alabama +4 sites NCT06283966
This trial is looking for adults aged 40 to 80 with Chronic Obstructive Pulmonary Disease (COPD). Participants will receive a combination inhaler treatment and attend study visits for assessments.
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
PHASE2 Birmingham, Alabama +4 sites NCT07082738
This trial is looking for people with moderate to very severe COPD to test the effects of a new drug called AZD6793. Participants will take AZD6793 or a placebo and help researchers learn about its safety and effectiveness.
Recruiting

Where the COPD studies are in Iowa

  • University of Iowa, Iowa City3 trials
  • Central Iowa Hospital Corp - UnityPoint Health, Des Moines1 trial
  • Research Site, Sioux City1 trial
  • Research Site, West Des Moines1 trial
  • The Iowa Clinic, West Des Moines1 trial

Counts are recruiting studies listing at least one site in Iowa, from ClinicalTrials.gov, refreshed every two days.

COPD clinical trials in Iowa: common questions

How many COPD clinical trials are recruiting in Iowa?
TrialFinder currently lists 7 recruiting COPD clinical trials with study sites in Iowa. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are COPD clinical trials located in Iowa?
Study sites for the COPD trials listed on this page include Des Moines, Iowa City. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a COPD clinical trial in Iowa?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many COPD trials in Iowa also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a COPD clinical trial in Iowa?
Each study sets its own criteria based on age, COPD diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need to quit smoking to join a COPD trial?
Most COPD trials accept current smokers; some require that you have stopped, and smoking-cessation trials are specifically for people who still smoke. The listing states the rule.
What tests confirm COPD for a trial?
Spirometry, a breathing test done at the site before and after a bronchodilator, which gives the lung function figure trials use to set their range. You do not need recent results to ask.
Will I keep using my inhalers during a trial?
Yes. Trials add the study treatment to your maintenance inhalers or supply a standardized equivalent, and a rescue inhaler is always permitted.
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COPD trials investigate bronchodilators, anti-inflammatory biologics, pulmonary rehabilitation, and lung-volume reduction procedures for chronic obstructive lung disease.

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