Stroke Trials / Trials in Iowa
20 Recruiting Trials

Clinical Trials
for Stroke in Iowa

20 clinical trials for Stroke are currently recruiting participants at study sites in Iowa. Study-related care is provided at no cost.

20
Recruiting trials
12
Study sites
3
Cities
8
Industry-sponsored
1
Phase 2
1
Phase 3

Stroke clinical trials in Iowa: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Iowa, recruiting stroke studies are concentrated in Iowa City, West Des Moines and Cedar Rapids. 8 of the 20 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 20 of 20 recruiting Stroke trials in Iowa

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
NA Tucson, Arizona +4 sites NCT03821129
This trial is looking for patients who have had a recent stroke and also have a condition called Patent Foramen Ovale (PFO). Participants will receive a device to help reduce the risk of future strokes.
Recruiting
Real-time Personalized Brain State-dependent TMS After Stroke
NA Iowa City, Iowa NCT06533176
This trial is looking for people who have some weakness in one arm after having a stroke. Participants will receive a specific type of brain stimulation to see if it helps improve arm function better than standard methods.
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
N/A Birmingham, Alabama +4 sites NCT05338697
This trial is looking for adults who have had a stroke and are experiencing motor difficulties in one arm. Participants will undergo specific tests and procedures to help researchers understand recovery outcomes.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
The Pivotal Study of RapidPulseTM Aspiration System
NA Torrance, California +4 sites NCT06029491
This trial is looking for adults aged 18 to 80 who have had a stroke within the last 8 hours. Participants will receive a treatment to remove a blood clot in the brain and will be monitored for 90 days.
Recruiting
Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe
NA Iowa City, Iowa +4 sites NCT06825897
This trial is looking for adults with suspected acute stroke caused by a blockage in a large blood vessel. Participants will either go directly to a special imaging room or first be seen in the emergency department to find out which approach helps them recover better.
Recruiting
Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe
NA Iowa City, Iowa +3 sites NCT05983757
This trial is looking for adults who have had a specific type of stroke and are eligible for a certain treatment. Participants will receive a procedure to remove a blood clot instead of standard medical care.
Recruiting
StrokeNet Thrombectomy Endovascular Platform
NA Birmingham, Alabama +4 sites NCT06289985
This trial is looking for people who have had a suspected ischemic stroke due to a blockage in a large or medium blood vessel in the brain. Participants will be assessed to determine if they can receive a treatment called endovascular thrombectomy.
Recruiting
EnDOvascular Therapy for Late WiNdow IschEmic Stroke Patients Selected bY AutoMatic Plain ComputErized Tomography
NA Iowa City, Iowa +1 sites NCT07001852
This trial is looking for people who have had a stroke and have a blood clot blocking a brain artery. By participating, I will undergo a standard brain scan to find out if I qualify for a specific treatment that could help my recovery.
Recruiting
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
N/A Phoenix, Arizona +4 sites NCT04916210
This trial is looking for adults who have had a stroke and want to help researchers learn more about how strokes affect thinking and memory. Participants will undergo evaluations to understand their recovery and brain health after a stroke.
Recruiting
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms
NA Phoenix, Arizona +4 sites NCT07143019
This trial is looking for adults with specific types of brain aneurysms who are interested in trying a new device treatment. Participants will need to agree to follow study procedures and provide consent.
Recruiting
Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter
NA Iowa City, Iowa +4 sites NCT06370182
This trial is looking for people who have had a recent stroke caused by a blocked large blood vessel. Participants will undergo a procedure using a special catheter to help restore blood flow to the brain.
Recruiting
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
NA Iowa City, Iowa NCT03481205
This trial is looking for adults aged 18 to 80 who have symptoms of an acute stroke caused by a blocked blood vessel. Participants will use a special device to help improve their condition while being transported by helicopter to a hospital.
Recruiting
Genetic Risk Factor for Heat Stroke
N/A Iowa City, Iowa NCT06847256
This trial is looking for adults who are carrying the cystic fibrosis gene or are not carriers. Participants will answer questions about their health and experience a heat challenge in a sauna.
Recruiting
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
PHASE3 Birmingham, Alabama +4 sites NCT03907046
This trial is looking for adults who have had a recent brain bleed and have atrial fibrillation. Participants will compare the effects of a medication called apixaban with aspirin to see which better prevents strokes or death.
Recruiting
PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic Brain Injury, or Brain Surgery
NA Cedar Rapids, Iowa +1 sites NCT07185971
This trial is looking for people who have lost part of their vision due to a stroke, brain injury, or brain surgery. Participants will use a virtual reality device at home or in the office for eight weeks, attending three sessions each week to see if their vision improves.
Recruiting
CoMind Early Feasibility Study
N/A Phoenix, Arizona +4 sites NCT06368648
This trial is looking for adults with serious brain issues who are already receiving invasive brain pressure monitoring. Participants will help test a new, non-surgical device designed to measure brain pressure safely.
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NA Birmingham, Alabama +4 sites NCT05963698
This trial is looking for people with atrial fibrillation who are at high risk of stroke, even while taking blood thinners. Participants will undergo a procedure to block a specific part of the heart to see if it helps prevent strokes.
Recruiting
Encore PFO Closure Device - The PerFOrm Trial
NA West Des Moines, Iowa +4 sites NCT05537753
This trial is looking for patients with a condition called PFO who have had a recent unexplained stroke. Participants will have the opportunity to receive a device to help close the PFO.
Recruiting
See all 20 Stroke trials in Iowa

Where the Stroke studies are in Iowa

Research sites running the most studies
  • University of Iowa, Iowa City8 trials
  • University of Iowa Hospitals & Clinics, Iowa City3 trials
  • Catholic Health Initiatives- Iowa Corp dba Iowa Heart, West Des Moines1 trial
  • Dr. D. M. Fitzgerald & Associates, Cedar Rapids1 trial
  • Mercy One Iowa Heart Center, West Des Moines1 trial
  • MercyOne Iowa Heart Center, West Des Moines1 trial
By city

Counts are recruiting studies listing at least one site in Iowa, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Iowa: common questions

How many Stroke clinical trials are recruiting in Iowa?
TrialFinder currently lists 20 recruiting Stroke clinical trials with study sites in Iowa. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Iowa?
Study sites for the Stroke trials listed on this page include Iowa City, Cedar Rapids, West Des Moines. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Iowa?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Iowa also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Iowa?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
Stroke Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Stroke Trials

Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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