Stroke Trials / Trials in Kentucky
12 Recruiting Trials

Clinical Trials
for Stroke in Kentucky

12 clinical trials for Stroke are currently recruiting participants at study sites in Kentucky. Study-related care is provided at no cost.

12
Recruiting trials
13
Study sites
3
Cities
3
Industry-sponsored
1
Phase 2
2
Phase 3

Stroke clinical trials in Kentucky: what to expect

Stroke trials come in three kinds. Acute treatment trials enroll within hours of a stroke, inside the hospital, and are not something you apply to. Recovery and rehabilitation trials enroll from a few weeks to many years after a stroke and test intensive therapy, robotics, brain and nerve stimulation, virtual reality and medicines meant to help the brain rewire. Prevention trials test blood thinners, cholesterol and blood pressure treatments and procedures to lower the chance of a second stroke.

In Kentucky, recruiting stroke studies are concentrated in Lexington, Louisville and Prospect. 3 of the 12 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who stroke trials usually look for

Listings state the time since stroke, the type (a clot or a bleed) and the kind of difficulty they study, such as arm and hand weakness, walking, speech or vision, often with a range on a standard scale that the study therapist scores. Many recovery trials enroll people six months or more after their stroke, so an older stroke does not rule you out. Prevention trials look for a stroke or mini-stroke in a recent window plus a specific risk factor such as atrial fibrillation. Most require that you can give consent and take part in sessions.

What taking part involves

Rehabilitation trials are intensive: several sessions a week for four to twelve weeks, with assessments by a therapist before, after and some months later, and sometimes an MRI. The comparison group often receives standard therapy or the same program later. Prevention trials are long and light: a study medicine or placebo added to usual care, visits every few months for several years. Study care and equipment are free and travel is usually reimbursed; a family member is welcome at visits.

Questions worth asking the study team

How many sessions are required and where; whether a comparison group receives the therapy later; whether current rehabilitation can continue; what the assessments involve; and whether transport can be arranged.

Showing 12 of 12 recruiting Stroke trials in Kentucky

Treatment With Endovascular Intervention for STroke Patients With Existing Disability
N/A Birmingham, Alabama +4 sites NCT05911568
This trial is looking for adults who had a stroke and have moderate to severe disability before it. Participants will compare two treatment options: a procedure to remove blood clots or regular medical care without the procedure.
Recruiting
Genetic and Environmental Risk Factors for Hemorrhagic Stroke
N/A Louisville, Kentucky +4 sites NCT00682695
This trial is looking for adults who have had a hemorrhagic stroke. Participants will provide consent for interviews, blood pressure checks, and blood sampling.
Recruiting
Stroke Thrombectomy and Aneurysm Registry
N/A Birmingham, Alabama +4 sites NCT04994756
This trial is looking for patients undergoing surgery for brain injuries. Participants will help collect information about their treatment and outcomes.
Recruiting
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
PHASE3 Mobile, Alabama +4 sites NCT05611242
This trial is looking for adults aged 18 to 79 who have had an acute ischemic stroke. Participants will receive a specific treatment for blocked arteries in the brain to see if it's more effective than other approaches.
Recruiting
Strategy for Improving Stroke Treatment Response
PHASE2 Birmingham, Alabama +4 sites NCT05948566
This trial is looking for adults who have had a suspected ischemic stroke. Participants will receive a treatment called TS23 to see how safe and effective it is within a specific time after their stroke.
Recruiting
Rapid Evacuation and Access of Cerebral Hemorrhage Trial
NA Birmingham, Alabama +4 sites NCT06870812
This trial is looking for adults with a specific type of brain bleed to compare surgery with standard medical care. Participants will receive either surgery to remove blood from the brain or regular medical treatment.
Recruiting
FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions
N/A Lexington, Kentucky +4 sites NCT07749170
Recruiting
Brain, Blood And Clot or Tissue Registry And Collaboration
N/A Lexington, Kentucky NCT03153683
This trial is looking for adults who have cerebrovascular disease or may have it. You will be asked to provide blood and tissue samples during certain medical procedures at the University of Kentucky.
Recruiting
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
PHASE3 Birmingham, Alabama +4 sites NCT03907046
This trial is looking for adults who have had a recent brain bleed and have atrial fibrillation. Participants will compare the effects of a medication called apixaban with aspirin to see which better prevents strokes or death.
Recruiting
PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic Brain Injury, or Brain Surgery
NA Prospect, Kentucky +1 sites NCT07185971
This trial is looking for people who have lost part of their vision due to a stroke, brain injury, or brain surgery. Participants will use a virtual reality device at home or in the office for eight weeks, attending three sessions each week to see if their vision improves.
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NA Birmingham, Alabama +4 sites NCT05963698
This trial is looking for people with atrial fibrillation who are at high risk of stroke, even while taking blood thinners. Participants will undergo a procedure to block a specific part of the heart to see if it helps prevent strokes.
Recruiting
Augmented Renal Clearance in Neurocritical Care
N/A Lexington, Kentucky +2 sites NCT07410624
This trial is looking for adults with life-threatening brain conditions to help understand how their kidneys affect medication dosing. Participants will need to be in the ICU and provide consent for urine collection to monitor kidney function.
Recruiting
See all 12 Stroke trials in Kentucky

Where the Stroke studies are in Kentucky

Research sites running the most studies
  • University of Louisville, Louisville3 trials
  • University of Louisville Hospital, Louisville2 trials
  • Babtist Health Lexington, Lexington1 trial
  • Baptist Health Lexington, Lexington1 trial
  • Baptist Health Louisville, Louisville1 trial
  • Baptist Healthcare System, Inc., Lexington1 trial
By city

Counts are recruiting studies listing at least one site in Kentucky, from ClinicalTrials.gov, refreshed every two days.

Stroke clinical trials in Kentucky: common questions

How many Stroke clinical trials are recruiting in Kentucky?
TrialFinder currently lists 12 recruiting Stroke clinical trials with study sites in Kentucky. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Stroke clinical trials located in Kentucky?
Study sites for the Stroke trials listed on this page include Louisville, Lexington, Prospect. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Stroke clinical trial in Kentucky?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Stroke trials in Kentucky also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Stroke clinical trial in Kentucky?
Each study sets its own criteria based on age, Stroke diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
My stroke was years ago. Are there still trials for me?
Yes. Many recovery trials enroll people six months or more after a stroke, and some accept strokes from many years earlier, because they study whether therapy can still improve movement or speech.
What are stroke rehabilitation trials like?
Intensive and hands-on: therapy sessions several times a week for one to three months, sometimes with a device or stimulation added, and assessments before and after. The comparison group usually gets standard therapy or the program at a later date.
Can a family member join a trial if they cannot consent for themselves?
Some trials allow a legally authorized representative to consent on a participant's behalf, particularly acute and prevention studies; most rehabilitation trials need the participant's own consent and active participation. Ask the study team.
Stroke Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Stroke Trials

Stroke trials cover thrombolytic agents, mechanical thrombectomy techniques, neuroprotective drugs, and intensive rehabilitation programmes for acute and chronic stroke.

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