Kidney Disease Trials / Trials in Kentucky
8 Recruiting Trials

Clinical Trials
for Kidney Disease in Kentucky

8 clinical trials for Kidney Disease are currently recruiting participants at study sites in Kentucky. Study-related care is provided at no cost.

8
Recruiting trials
8
Study sites
3
Cities
8
Industry-sponsored
3
Phase 2
4
Phase 3

Kidney Disease clinical trials in Kentucky: what to expect

Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.

In Kentucky, recruiting kidney disease studies are concentrated in Louisville, Lexington and Bowling Green. 8 of the 8 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who kidney disease trials usually look for

Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.

What taking part involves

Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.

Questions worth asking the study team

Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.

Showing 8 of 8 recruiting Kidney Disease trials in Kentucky

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
PHASE3 Huntsville, Alabama +4 sites NCT06531824
This trial is looking for adults with chronic kidney disease who are at risk of it getting worse. Participants will take a study medicine called BI 690517 along with empagliflozin or just empagliflozin for the study duration.
Recruiting
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
PHASE3 Birmingham, Alabama +4 sites NCT07107945
This trial is looking for children aged 2 to 17 who have chronic kidney disease. Participants will take a daily tablet for 6 months followed by 1 year of another medication, with regular check-ups to monitor their health.
Recruiting
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
PHASE2 Decatur, Alabama +4 sites NCT05485961
This trial is looking for adults with end stage kidney disease who are undergoing dialysis and have systemic inflammation. Participants will receive a study medication or a placebo to see how it affects heart health.
Recruiting
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
PHASE2 Decatur, Alabama +4 sites NCT06830629
This trial is looking for adults with a specific genetic risk for kidney disease and ongoing protein in their urine. Participants will take the drug MZE829 to see how it affects their kidney condition.
Recruiting
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
NA Bullhead City, Arizona +4 sites NCT06001827
This trial is looking for adults with chronic kidney disease who need a new arteriovenous fistula for dialysis. Participants will receive a special wrap during the procedure and will follow up with the study team for 36 months.
Recruiting
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
PHASE3 Huntsville, Alabama +4 sites NCT07624305
This trial is looking for adults with chronic kidney disease stages 3b and 4. Participants will take a daily combination of two medications to see how well they work together compared to taking just one of them.
Recruiting
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
PHASE1 Huntsville, Alabama +4 sites NCT06749457
This trial is looking for healthy adults or adults with end-stage kidney disease on hemodialysis. Participants will receive a medication called AZD7760 through an intravenous infusion to study its safety and how it moves through the body.
Recruiting
Persona Revision Knee System Outcomes
N/A Fayetteville, Arkansas +4 sites NCT04821154
This trial is looking for patients who have had knee surgery and need additional treatment. Participants will be evaluated for the safety and effectiveness of the Persona Revision Knee System.
Recruiting
See all 8 Kidney Disease trials in Kentucky

Where the Kidney Disease studies are in Kentucky

Research sites running the most studies
  • Research Site, Louisville2 trials
  • Arthroplasty Foundation Inc., Louisville1 trial
  • Nephrology Associates of Kentuckiana, PSC, Louisville1 trial
  • Novak Center for Children's Health, Louisville1 trial
  • Research Site, Bowling Green1 trial
  • Research Site, Lexington1 trial
By city

Counts are recruiting studies listing at least one site in Kentucky, from ClinicalTrials.gov, refreshed every two days.

Kidney Disease clinical trials in Kentucky: common questions

How many Kidney Disease clinical trials are recruiting in Kentucky?
TrialFinder currently lists 8 recruiting Kidney Disease clinical trials with study sites in Kentucky. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Kentucky?
Sites for these Kidney Disease trials are spread across Kentucky. Open any trial to see its full list of participating locations and contact details.
Do I need insurance to join a Kidney Disease clinical trial in Kentucky?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Kentucky also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Kentucky?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
Kidney Disease Trials in Other States
Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming
Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

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About Kidney Disease Trials

Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.

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