11 Recruiting Trials

Clinical Trials
for Kidney Disease in Mississippi

11 clinical trials for Kidney Disease are currently recruiting participants at study sites in Mississippi. Study-related care is provided at no cost.

11
Recruiting trials
16
Study sites
8
Cities
9
Industry-sponsored
5
Phase 2
5
Phase 3

Kidney Disease clinical trials in Mississippi: what to expect

Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.

In Mississippi, recruiting kidney disease studies are concentrated in Tupelo, Brookhaven, Columbus and Jackson, with sites in 4 other cities. 9 of the 11 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who kidney disease trials usually look for

Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.

What taking part involves

Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.

Questions worth asking the study team

Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.

Showing 11 of 11 recruiting Kidney Disease trials in Mississippi

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
PHASE3 Huntsville, Alabama +4 sites NCT06531824
This trial is looking for adults with chronic kidney disease who are at risk of it getting worse. Participants will take a study medicine called BI 690517 along with empagliflozin or just empagliflozin for the study duration.
Recruiting
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
PHASE3 Huntsville, Alabama +4 sites NCT07753993
This trial is looking for adults with chronic kidney disease to see how well elecoglipron works compared to a placebo. Participants must be on certain medications for their condition before joining the study.
Recruiting
The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity
N/A Jackson, Mississippi NCT07052539
This trial is looking for adults with obesity, chronic kidney disease, and heart failure. Participants will help researchers learn how these conditions affect kidney function.
Recruiting
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
PHASE2 Decatur, Alabama +4 sites NCT05485961
This trial is looking for adults with end stage kidney disease who are undergoing dialysis and have systemic inflammation. Participants will receive a study medication or a placebo to see how it affects heart health.
Recruiting
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
PHASE2 Alabaster, Alabama +4 sites NCT05312879
This trial is looking for adults and children with a specific type of kidney disease caused by genetics. Participants will receive the drug VX-147 to assess its effectiveness and safety.
Recruiting
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
PHASE2 Decatur, Alabama +4 sites NCT06830629
This trial is looking for adults with a specific genetic risk for kidney disease and ongoing protein in their urine. Participants will take the drug MZE829 to see how it affects their kidney condition.
Recruiting
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
PHASE2 Alabaster, Alabama +4 sites NCT06824987
This trial is looking for adults of African descent with a specific type of kidney disease. Participants will take the drug AZD2373 and attend check-ups to see how well the treatment works and if it is safe.
Recruiting
Incremental Hemodialysis: The TwoPlus Trial
NA Jackson, Mississippi +4 sites NCT05828823
This trial is looking for adults with kidney problems who need dialysis. Participants will either start a new type of dialysis called incremental hemodialysis or a traditional one. The trial will follow them for about two years to compare the outcomes.
Recruiting
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
PHASE3 Granada Hills, California +4 sites NCT06933472
This trial is looking for patients who are on dialysis and have high blood phosphate levels. Participants will take a medication called AP301 or a similar substance for a period of time to see if it helps lower their phosphate levels and improve their quality of life.
Recruiting
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
PHASE1 Huntsville, Alabama +4 sites NCT06749457
This trial is looking for healthy adults or adults with end-stage kidney disease on hemodialysis. Participants will receive a medication called AZD7760 through an intravenous infusion to study its safety and how it moves through the body.
Recruiting
SPYRAL GEMINI Pilot Study
NA Stanford, California +4 sites NCT06907147
This trial is looking for people with high blood pressure who are between 18 and 80 years old. Participants will receive a treatment aimed at lowering blood pressure.
Recruiting

Where the Kidney Disease studies are in Mississippi

  • Research Site, Tupelo3 trials
  • Nephrology Associates, P.C. - Columbus, Columbus2 trials
  • University of Mississippi Medical Center, Jackson2 trials
  • - Nephrology and Hypertension Associates Ltd, Tupelo1 trial
  • G.V. (Sonny) Montgomery VAMC, Jackson1 trial
  • Nephrology & Hypertension Associates Ltd - Tupelo, Tupelo1 trial

Counts are recruiting studies listing at least one site in Mississippi, from ClinicalTrials.gov, refreshed every two days.

Kidney Disease clinical trials in Mississippi: common questions

How many Kidney Disease clinical trials are recruiting in Mississippi?
TrialFinder currently lists 11 recruiting Kidney Disease clinical trials with study sites in Mississippi. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Mississippi?
Study sites for the Kidney Disease trials listed on this page include Jackson. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in Mississippi?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Mississippi also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Mississippi?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
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Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.

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