26 Recruiting Trials

Clinical Trials
for Kidney Disease in Colorado

26 clinical trials for Kidney Disease are currently recruiting participants at study sites in Colorado. Study-related care is provided at no cost.

26
Recruiting trials
21
Study sites
7
Cities
14
Industry-sponsored
10
Phase 2
9
Phase 3

Kidney Disease clinical trials in Colorado: what to expect

Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.

In Colorado, recruiting kidney disease studies are concentrated in Aurora, Denver, Arvada and Englewood, with sites in 3 other cities. 14 of the 26 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who kidney disease trials usually look for

Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.

What taking part involves

Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.

Questions worth asking the study team

Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.

Showing 20 of 26 recruiting Kidney Disease trials in Colorado

NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
NA Denver, Colorado +1 sites NCT06810622
This trial is looking for adults with advanced kidney disease to test a program designed to improve kidney treatment and patient involvement. Participants will not be pregnant, incarcerated, or under 18 years old.
Recruiting
Supporting VETerans With Kidney Disease Through Food As Medicine
NA Aurora, Colorado NCT07194733
This trial is looking for Veterans with kidney disease and food insecurity. Participants will receive produce boxes and share their experiences in interviews.
Recruiting
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
PHASE2 Aurora, Colorado +3 sites NCT05822609
This trial is looking for adults with type 1 diabetes and kidney disease to see how a medication called semaglutide affects their condition. Participants will need to complete some tests and take the study medication for 26 weeks.
Recruiting
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
PHASE3 Huntsville, Alabama +4 sites NCT06531824
This trial is looking for adults with chronic kidney disease who are at risk of it getting worse. Participants will take a study medicine called BI 690517 along with empagliflozin or just empagliflozin for the study duration.
Recruiting
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
PHASE3 Huntsville, Alabama +4 sites NCT07753993
This trial is looking for adults with chronic kidney disease to see how well elecoglipron works compared to a placebo. Participants must be on certain medications for their condition before joining the study.
Recruiting
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
PHASE2 Aurora, Colorado +4 sites NCT06717698
This trial is looking for adults with chronic kidney disease, with or without type 2 diabetes, who are living with overweight or obesity. Participants will receive either a new medicine, a standard medicine, or a placebo for up to 43 weeks.
Recruiting
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
PHASE4 Aurora, Colorado NCT06860711
This trial is looking for children over 18 months old with chronic kidney disease who are scheduled for urologic surgery. Participants will take NSAIDs after the surgery to help understand if these medications increase the risk of kidney injury.
Recruiting
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
PHASE2 Decatur, Alabama +4 sites NCT05485961
This trial is looking for adults with end stage kidney disease who are undergoing dialysis and have systemic inflammation. Participants will receive a study medication or a placebo to see how it affects heart health.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
PHASE2 Huntsville, Alabama +4 sites NCT07355296
This trial is looking for adults and older teenagers with specific kidney diseases who have been stable on certain medications for at least a couple of months. They need to be in good enough health with manageable blood pressure. However, if you have had an organ transplant or recently used strong immunosuppressive treatments, you can't participate.
Recruiting
Equol and Vascular Function in Women With Chronic Kidney Disease
PHASE2 Aurora, Colorado NCT07194590
This trial is looking for postmenopausal women aged 50 and older with chronic kidney disease (CKD) stages 3 or 4. Participants will take equol supplements for 12 weeks to see how it affects their vascular function.
Recruiting
Inspiratory Muscle Strength Training in Chronic Kidney Disease
NA Aurora, Colorado NCT04911491
This trial is looking for older adults with chronic kidney disease and high blood pressure. Participants will do a special breathing exercise program to see if it helps lower blood pressure.
Recruiting
Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.
PHASE3 Denver, Colorado +4 sites NCT06858319
This trial is looking for adults who have completed another zigakibart study. Participants will receive zigakibart treatment to see if it is safe and effective for long-term use in their condition.
Recruiting
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
PHASE3 Aurora, Colorado +4 sites NCT05931276
This trial is looking for patients on hemodialysis who take certain beta blockers. Participants will receive either metoprolol or carvedilol to see how these medications affect heart health.
Recruiting
Acute Equol Supplementation and Vascular Function in Women With and Without CKD
PHASE2 Aurora, Colorado NCT06128278
This trial is looking for postmenopausal women with and without chronic kidney disease (CKD) to see how equol affects blood vessel function. Participants will take equol and attend follow-up assessments one to three hours later.
Recruiting
Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength
NA Aurora, Colorado +1 sites NCT06607913
This trial is looking for older adults with chronic kidney disease who have been hospitalized. Participants will help improve recovery from muscle weakness after being in the hospital through exercise and monitoring.
Recruiting
A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
PHASE3 Aurora, Colorado +4 sites NCT03633708
This trial is looking for children under 18 with hyperparathyroidism and chronic kidney disease who are on hemodialysis. Participants will be monitored and treated with etelcalcetide during the study.
Recruiting
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
PHASE3 Lone Tree, Colorado +4 sites NCT06933472
This trial is looking for patients who are on dialysis and have high blood phosphate levels. Participants will take a medication called AP301 or a similar substance for a period of time to see if it helps lower their phosphate levels and improve their quality of life.
Recruiting
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
PHASE3 Aurora, Colorado +4 sites NCT06217302
This trial is looking for adults with type 1 diabetes and diabetic kidney disease. Participants will take either a study drug or a placebo for three years, while receiving education on managing their diabetes.
Recruiting
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
PHASE1 Huntsville, Alabama +4 sites NCT06749457
This trial is looking for healthy adults or adults with end-stage kidney disease on hemodialysis. Participants will receive a medication called AZD7760 through an intravenous infusion to study its safety and how it moves through the body.
Recruiting

Where the Kidney Disease studies are in Colorado

  • Colorado Kidney Care, Denver3 trials
  • University of Colorado Anschutz Medical Campus, Aurora3 trials
  • Children's Hospital Colorado, Aurora2 trials
  • Colorado Kidney Care Nephrology, Denver2 trials
  • Research Site, Arvada2 trials
  • Research Site, Denver2 trials

Counts are recruiting studies listing at least one site in Colorado, from ClinicalTrials.gov, refreshed every two days.

Kidney Disease clinical trials in Colorado: common questions

How many Kidney Disease clinical trials are recruiting in Colorado?
TrialFinder currently lists 26 recruiting Kidney Disease clinical trials with study sites in Colorado. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Colorado?
Study sites for the Kidney Disease trials listed on this page include Denver, Aurora, Lone Tree. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in Colorado?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Colorado also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Colorado?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
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Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.

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