No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
55 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
250 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for older adults with chronic kidney disease who have been hospitalized. Participants will help improve recovery from muscle weakness after being in the hospital through exercise and monitoring.
Are You a Good Fit for This Trial?
You may be able to join if
I am over 55 years old.
I have stage 3-4 chronic kidney disease or an eGFR less than 45.
You may not be able to join if
I have poorly controlled high blood pressure over 160/100.
I have had a heart attack in the past 6 months.
I have congestive heart failure class III or IV.
I have chest pain while resting or exercising.
I passed out in the past year without knowing why.
I have chronic obstructive pulmonary disease that requires home oxygen.
I have a history of significant spinal osteoarthritis or stenosis.
I have dementia.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose of this collaborative study inv…
The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose of this collaborative study involving Denver and Baltimore VAMC sites is to improve health through the detection and rehabilitation management of hospital-acquired weakness in those with CKD. The study goals include identifying and monitoring the optimal muscle assessment sites in clinical settings, examining how muscle health impacts length of hospital stay and physical resilience, and determining how home-based and supervised exercise comparatively addresses post-hospitalization physical resilience using performance tests and Veteran feedback.
Trial Locations
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City
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Status
Eligibility Criteria
Inclusion Criteria:
* Age \> 55 years
* Diagnosis of stage 3-4 CKD or an eGFR of \<45 mL/min/1.73m2
Exclusion Criteria:
* Cardiovascular risk: Poorly controlled hypertension (\>160/100)
* Coronary event in past 6 months
* Class III or IV CHF
* symptomatic angina at rest or during exercise
…
Inclusion Criteria:
* Age \> 55 years
* Diagnosis of stage 3-4 CKD or an eGFR of \<45 mL/min/1.73m2
Exclusion Criteria:
* Cardiovascular risk: Poorly controlled hypertension (\>160/100)
* Coronary event in past 6 months
* Class III or IV CHF
* symptomatic angina at rest or during exercise
* Syncope in past year, without known resolution of cause
* COPD requiring home oxygen
* Contraindications to resistance training, including history of intracranial or retinal bleeding; Diabetes with active proliferative retinopathy
* History of significant spinal osteoarthritis or spinal stenosis
* Dementia (on medical record review or mini-mental status exam score)
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