60 Recruiting Trials

Clinical Trials
for Diabetes in Colorado

60 clinical trials for Diabetes are currently recruiting participants at study sites in Colorado. Study-related care is provided at no cost.

60
Recruiting trials
37
Study sites
6
Cities
21
Industry-sponsored
13
Phase 2
13
Phase 3

Diabetes clinical trials in Colorado: what to expect

Diabetes is one of the largest areas of clinical research, and the trials differ a great deal by type. Type 2 studies most often test new glucose-lowering or weight-reducing medicines, once-weekly insulins, and combinations with GLP-1 drugs, in people whose A1c is above goal on their current treatment. Type 1 studies test automated insulin delivery systems, immune therapies for people recently diagnosed or at high risk, and cell-based approaches. Others focus on the complications: kidney disease, eye disease, nerve pain and foot ulcers.

In Colorado, recruiting diabetes studies are concentrated in Aurora, Denver, Arvada and Englewood, with sites in 2 other cities. 21 of the 60 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who diabetes trials usually look for

Type 2 trials typically ask for a confirmed diagnosis, an A1c in a stated range (often between 7 and 10.5 percent) and a stable dose of your current medicines for at least a few months. Many exclude recent insulin use, a recent heart attack or stroke, or kidney function below a cut-off. Type 1 trials are often limited by time since diagnosis and by age, and some enroll children and teenagers with a parent's consent.

You do not need to know your A1c or kidney numbers to ask about a trial; the site measures them at screening.

What taking part involves

Screening includes blood work and a review of your history. Medicine trials usually last six months to three years with visits every one to three months, and many provide a glucose monitor and supplies for the duration. Some compare a new drug with a standard one rather than a placebo, so everyone receives active treatment; others include a placebo arm, and the consent form says which. Study drugs, devices, visits and labs are provided at no cost, and most trials pay for time and travel.

Questions worth asking the study team

Whether you would stay on your current medicines; whether there is a placebo group; how often visits are and whether any can be done remotely; and whether your own doctor will receive the results of study labs. If you have type 1 diabetes, ask whether the study uses your own pump or monitor.

Showing 20 of 60 recruiting Diabetes trials in Colorado

Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes
EARLY_PHASE1 Aurora, Colorado NCT05041491
This trial is looking for people who are at risk of developing type 2 diabetes to see how breaking up sitting time with brief physical activity can help improve blood sugar levels. Participants will be asked to follow specific activity routines and wear a fitness tracker.
Recruiting
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)
N/A Aurora, Colorado +1 sites NCT05008276
This trial is looking for teenagers with type 2 diabetes and obesity. Participants will help researchers learn how puberty affects kidney health in young people with diabetes.
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
PHASE3 Anniston, Alabama +4 sites NCT07064473
This trial is looking for adults with type 2 diabetes, high blood pressure, and heart disease. Participants will take either the study medication or a placebo daily for up to 4 years.
Recruiting
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
PHASE3 Aurora, Colorado +4 sites NCT07088068
This trial is looking for young people ages 1 to 25 who have recently been diagnosed with stage 3 type 1 diabetes. Participants will receive either teplizumab or a placebo through an IV to see how it affects their blood sugar control over 52 weeks.
Recruiting
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
PHASE3 Aurora, Colorado +4 sites NCT07222332
This trial is looking for children and adults who have recently been diagnosed with type 1 diabetes, specifically within the last 100 days. To join, they need to still show some signs of their pancreas working. However, people with other types of diabetes, serious heart problems, or certain health risks can’t participate.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
PHASE3 Birmingham, Alabama +4 sites NCT07662044
This trial is looking for adults with type 2 diabetes that is not well controlled. Participants will take elecoglipron alone or with another medication and compare the effects to a placebo.
Recruiting
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
PHASE3 Tucson, Arizona +4 sites NCT06739122
This trial is looking for children with Type 2 diabetes to test different doses of a medication called dulaglutide. Participation will last about 8 months and requires being treated with certain diabetes medications.
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
PHASE3 Aurora, Colorado +4 sites NCT07664553
This trial is looking for adults with type 2 diabetes who are already taking insulin and other medications to lower blood sugar. Participants will compare a new treatment called elecoglipron with a placebo to see how effective and safe it is.
Recruiting
Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes
PHASE3 Aurora, Colorado +1 sites NCT05819138
This trial is looking for adults with type 1 diabetes to learn about a medication called semaglutide. Participants will receive this medication to see how it affects their heart and kidney health.
Recruiting
Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes
PHASE2 Aurora, Colorado +4 sites NCT06535789
This trial is looking for pregnant women aged 18-40 who have gestational diabetes. Participants will try two types of insulin to see which one works better for controlling blood sugar after meals.
Recruiting
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
PHASE2 Aurora, Colorado +4 sites NCT07187531
This trial is looking for people aged 5 to 40 who have recently been diagnosed with Type 1 Diabetes. Participants will receive either the study medication or a placebo and will be monitored for safety and effectiveness.
Recruiting
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
PHASE1 Tucson, Arizona +4 sites NCT06783309
This trial is looking for teenagers and young adults aged 12-35 who have been diagnosed with Type 1 Diabetes in the last 6 months. Participants will take a study medication called CNP-103 and will be monitored for safety and effectiveness over about a year.
Recruiting
Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
PHASE2 Aurora, Colorado +4 sites NCT07216391
This trial is looking for people aged 4 to 34 who have early signs of Type 1 diabetes. Participants will receive either two infusions of ATG or 14 infusions of teplizumab and will be followed for up to 9 years.
Recruiting
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
PHASE2 Aurora, Colorado +4 sites NCT07142252
This trial is looking for people recently diagnosed with type 1 diabetes. Participants will take either the study drug or a placebo every two weeks for 26 weeks, followed by a 6-month check-up.
Recruiting
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
PHASE2 Aurora, Colorado +4 sites NCT07224321
This trial is looking for young people aged 6 to under 18 with newly diagnosed type 1 diabetes. Participants will take a medication called Afrezza along with another insulin for 13 weeks, with a possible option to continue for another 26 weeks.
Recruiting
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
PHASE2 Birmingham, Alabama +4 sites NCT05762107
This trial is looking for adults with type 1 diabetes who experience low blood sugar at night. Participants will receive either the study drug ZT-01 or a placebo for two weeks while using a glucose monitor to track their blood sugar levels.
Recruiting
Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Mellitus
PHASE2 Aurora, Colorado +4 sites NCT06964087
This trial is looking for adults with Type 1 Diabetes who are interested in testing a new treatment called OPT101. Participants will receive injections of the treatment or a placebo and will need to wear a continuous glucose monitor for the study's duration.
Recruiting
Precision Administration of Anti-thymocyte Globulin With or Without Verapamil
PHASE2 Aurora, Colorado +1 sites NCT06455319
This trial is looking for young people with type 1 diabetes who have been diagnosed for less than 100 days. Participants will receive a treatment that may help their insulin production and will need to follow specific health management during the study.
Recruiting
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
PHASE4 Denver, Colorado +1 sites NCT06983054
This trial is looking for adults with type 2 diabetes to study how salt intake affects a medication called ertugliflozin. Participants will take the medication and be monitored for changes related to their kidney health and blood pressure.
Recruiting
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
PHASE1 Aurora, Colorado +1 sites NCT05065372
This trial is looking for young people with type 1 diabetes who use automated insulin delivery systems or multiple daily insulin injections. Participants will take metformin for four months to see how it affects their health.
Recruiting

Where the Diabetes studies are in Colorado

  • University of Colorado Anschutz Medical Campus, Aurora7 trials
  • Barbara Davis Center, Aurora6 trials
  • University of Colorado, Aurora6 trials
  • Children's Hospital Colorado, Aurora5 trials
  • Barbara Davis Center for Diabetes, Aurora4 trials
  • Barbara Davis Center for Childhood Diabetes, Aurora2 trials

Counts are recruiting studies listing at least one site in Colorado, from ClinicalTrials.gov, refreshed every two days.

Diabetes clinical trials in Colorado: common questions

How many Diabetes clinical trials are recruiting in Colorado?
TrialFinder currently lists 60 recruiting Diabetes clinical trials with study sites in Colorado. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Diabetes clinical trials located in Colorado?
Study sites for the Diabetes trials listed on this page include Aurora, Denver. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Diabetes clinical trial in Colorado?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Diabetes trials in Colorado also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Diabetes clinical trial in Colorado?
Each study sets its own criteria based on age, Diabetes diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Can I join a diabetes clinical trial if I am already on medication?
Usually yes. Most type 2 diabetes trials enroll people on metformin or other oral medicines and test a new treatment on top of them; some require a stable dose for a few months first. Trials that exclude insulin or a specific drug say so in their criteria.
Do I need to know my A1c to apply?
No. Trials state an A1c range, but the study site measures it at the screening visit. You only need to know that you have been diagnosed and which type.
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Diabetes clinical trials study new treatments for Type 1, Type 2, and gestational diabetes, including insulin therapies, diet interventions, and islet-cell transplants.

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